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474317-28-7

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474317-28-7 Usage

General Description

(S)-2-(1-Hydroxy-1-methylethyl)pyrrolidine hydrochloride is a chemical compound used in the pharmaceutical industry as a chiral building block for the synthesis of various pharmaceuticals and fine chemicals. It is a crystalline solid with a molecular formula of C7H15NO?HCl. (S)-2-(1-Hydroxy-1-methylethyl)pyrrolidine hydrochloride is a chiral pyrrolidine derivative with a hydroxyl group and a methyl substituent, which makes it an important intermediate in the synthesis of various pharmaceutical compounds. It is commonly used as a key intermediate in the synthesis of drugs with biological activity, such as antipsychotic and antidepressant medications. Additionally, (S)-2-(1-Hydroxy-1-methylethyl)pyrrolidine hydrochloride is also used in the production of agrochemicals and other specialty chemicals due to its unique properties and versatility in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 474317-28-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,4,3,1 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 474317-28:
(8*4)+(7*7)+(6*4)+(5*3)+(4*1)+(3*7)+(2*2)+(1*8)=157
157 % 10 = 7
So 474317-28-7 is a valid CAS Registry Number.

474317-28-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-pyrrolidin-2-ylpropan-2-ol,hydrochloride

1.2 Other means of identification

Product number -
Other names (S)-2-(pyrrolidin-2-yl)propan-2-ol hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:474317-28-7 SDS

474317-28-7Relevant articles and documents

New route for the synthesis of chiral hydrazine SADP

Jia, Tao

, p. 325 - 328 (2012)

A convenient route for the synthesis of (S)-1-amino-2-(1-methoxy-1- methylethyl)pyrrolidine (SADP) was established. The route involved three key steps viz. the Grignard addition to the N-Boc-proline ester (1), nitrosation to the aminoalcohol hydrochloride (3) and O-methylation to the alcohol group of N-nitrosopyrrolidine (4). (S)-1,1-dimethyl-tetrahydropyrrolo[1,2-c]oxazol-3-one (6) was also obtained via the reaction of (S)-1-Boc-2-(1-hydroxy-1-methylethyl) pyrrolidine (2) with sodium hydride.

Novel chiral amine oxide ligand and preparation method thereof

-

, (2019/05/15)

The invention provides a novel chiral amine oxide ligand and a preparation method thereof. The method uses a simple amino acid or an amino acid derivative as a raw material, the raw material is modified, the modified material reacts with substances such as a coupling agent and an alkali, and therefore the pincher configuration chiral ligand compound is obtained, that is, the chiral amine oxide ligand. The chiral amine oxide ligand provided by the invention has a structure of a non-simple linear chain, has a soft skeleton in the molecular structure, contains a recognition gene containing heteroatoms such as oxygen or nitrogen, and can well coordinate with a series of metals and realize high enantioselectivity and high reactivity in a non-symmetric reaction; and the preparation method is simple, the steps are few, and the raw materials are cheap and easy to obtain.

NOVEL BETULINIC SUBSTITUTED AMIDE DERIVATIVES AS HIV INHIBITORS

-

Page/Page column 61-62, (2017/02/24)

The present invention relates to novel betulinic substituted amide compounds of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, Z3 and are Formula (II) as defined herein. The invention novel betulinic substituted amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.

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