4748-96-3

Basic information

• Product Name: ethyl 3-(2,2-dimethylhydrazinyl)propanoate
• CAS NO: 4748-96-3
• Molecular Formula: C₇H₁₆N₂O₂
• Molecular Weight: 160.2141
• Mol File: 4748-96-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 213.4°C at 760 mmHg
• Flash Point: 82.9°C
• Density: 0.979g/cm³
• Vapor Pressure: 0.164mmHg at 25°C
• Refractive Index: 1.445
• CAS DataBase Reference: ethyl 3-(2,2-dimethylhydrazinyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(2,2-dimethylhydrazinyl)propanoate(4748-96-3)
• EPA Substance Registry System: ethyl 3-(2,2-dimethylhydrazinyl)propanoate(4748-96-3)

Safety Data

• Hazardous Substances Data: 4748-96-3(Hazardous Substances Data)

Upstream product

• 57-14-7 N,N-Dimethylhydrazine 
• 140-88-5 ethyl acrylate 

Downstream Products

• 76144-81-5 meldonium 
• 118603-65-9 2-(3-ethoxy-3-oxopropyl)-1-ethyl-1,1-dimethylhydrazinium iodide 

Relevant articles and documents

Improvement method for preparation technology of 3-(2-ethyl-2,2-dimethyl hydrazinyl) ethyl propionate iodate bulk drug

The invention relates to an improvement method for a preparation technology of a 3-(2-ethyl-2,2-dimethyl hydrazinyl) ethyl propionate iodate bulk drug being an important antiarrhythmic drug. In orderto overcome the defects of raw material and intermediate instability, many reaction by-products and the like of a 1,1-dimethylhydrazine and ethyl acrylate addition reaction, in a process from the addition reaction to an alkylation reaction, special measures for treating impurities, controlling the impurities, passivating the impurities and the like are adopted for obtaining a high-purity 3-(2-ethyl-2,2-dimethyl hydrazinyl) ethyl propionate iodate bulk drug crystal; various impurity residue varieties of a final target compound and the step of macroporous resin purification in industrial production are avoided; all impurity sources are controlled and eliminated; and the advantages of commercial scale production, cost reduction, equipment simplicity and the like are realized.