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4-Chloro-2-methylphenylmagnesium bromide, with the molecular formula C7H8BrClMg, is a Grignard reagent that serves as a source of the 4-chloro-2-methylphenyl nucleophile. It is a versatile synthetic building block in organic chemistry, capable of participating in a wide range of chemical reactions, including nucleophilic addition, substitution, and coupling reactions.

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  • 480438-47-9 Structure
  • Basic information

    1. Product Name: 4-CHLORO-2-METHYLPHENYLMAGNESIUM BROMID&
    2. Synonyms: 4-chloro-2-methylphenylmagnesium bromide solution;4-Chloro-2-methylphenylmagnesium bromide solution 0.5 in THF;4-Chloro-2-methylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal;4-Chloro-2-MethylphenylMagnesiuM broMide, 0.50 M in 2-MeTHF;4-Chloro-2-MethylphenylMagnesiuM broMide, 0.50 M solution in 2-Methyltetrahydrofuran;4-Chloro-2-methylphenylmagnesium bromide solution 0.5 M in THF;2-Methyl-4-chlorophenylmagnesium bromide;magnesium,1-chloro-3-methylbenzene-4-ide,bromide
    3. CAS NO:480438-47-9
    4. Molecular Formula: C7H6BrClMg
    5. Molecular Weight: 229.78454
    6. EINECS: N/A
    7. Product Categories: Aryl;Grignard Reagents;Organometallic Reagents
    8. Mol File: 480438-47-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 65-67 °C
    3. Flash Point: 1 °F(lit.)
    4. Appearance: /
    5. Density: 0.959 g/mL at 25 °C
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. Sensitive: Air & Moisture Sensitive
    10. CAS DataBase Reference: 4-CHLORO-2-METHYLPHENYLMAGNESIUM BROMID&(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-CHLORO-2-METHYLPHENYLMAGNESIUM BROMID&(480438-47-9)
    12. EPA Substance Registry System: 4-CHLORO-2-METHYLPHENYLMAGNESIUM BROMID&(480438-47-9)
  • Safety Data

    1. Hazard Codes: F,C
    2. Statements: 11-14-19-22-34-40-37
    3. Safety Statements: 16-29-33-45-36/37/39-26
    4. RIDADR: UN 2924 3/PG 2
    5. WGK Germany: 1
    6. RTECS:
    7. HazardClass: 3
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 480438-47-9(Hazardous Substances Data)

480438-47-9 Usage

Uses

Used in Organic Synthesis:
4-Chloro-2-methylphenylmagnesium bromide is used as a reagent in organic synthesis for introducing the 4-chloro-2-methylphenyl group into various organic compounds. Its nucleophilic properties allow it to participate in a variety of chemical reactions, making it a valuable tool for creating complex organic molecules.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 4-chloro-2-methylphenylmagnesium bromide is used as an intermediate in the synthesis of various pharmaceuticals. Its ability to introduce the 4-chloro-2-methylphenyl group into organic compounds makes it a useful building block for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical industry, 4-chloro-2-methylphenylmagnesium bromide is utilized as an intermediate in the synthesis of agrochemicals. Its versatility in organic synthesis enables the creation of compounds with targeted pesticidal or herbicidal properties, contributing to the development of effective crop protection agents.

Check Digit Verification of cas no

The CAS Registry Mumber 480438-47-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,0,4,3 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 480438-47:
(8*4)+(7*8)+(6*0)+(5*4)+(4*3)+(3*8)+(2*4)+(1*7)=159
159 % 10 = 9
So 480438-47-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H6Cl.BrH.Mg/c1-6-3-2-4-7(8)5-6;;/h2,4-5H,1H3;1H;/q;;+1/p-1/rC7H6BrClMg/c1-5-4-6(9)2-3-7(5)10-8/h2-4H,1H3

480438-47-9 Well-known Company Product Price

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  • CAS number
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  • Alfa Aesar

  • (H54697)  4-Chloro-2-methylphenylmagnesium bromide, 0.50 M in 2-MeTHF   

  • 480438-47-9

  • 100ml

  • 4152.0CNY

  • Detail
  • Aldrich

  • (562262)  4-Chloro-2-methylphenylmagnesiumbromidesolution  0.5 M in THF

  • 480438-47-9

  • 562262-50ML

  • 3,690.18CNY

  • Detail

480438-47-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name magnesium,1-chloro-3-methylbenzene-4-ide,bromide

1.2 Other means of identification

Product number -
Other names 4-Chloro-2-methylphenylmagnesium bromide 0.5 M in Tetrahydrofuran

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:480438-47-9 SDS

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