4886-30-0

Basic information

• Product Name: 1H-Benzimidazole,1-butyl-(9CI)
• Synonyms: 1H-Benzimidazole,1-butyl-(9CI);N-Butylbenzimidazole;1-ButylbenziMidazole;1-butyl-1H-benzo[d]iMidazole;BenziMidazole, 1-butyl- (7CI,8CI);1H-BenziMidazole, 1-butyl-
• CAS NO: 4886-30-0
• Molecular Formula: C₁₁H₁₄N₂
• Molecular Weight: 174.246
• Product Categories: BENZIMIDAZOLE
• Mol File: 4886-30-0.mol

Chemical Properties

• Melting Point: 171-173℃
• Boiling Point: 296.9°C at 760 mmHg
• Flash Point: 133.4°C
• Appearance: /
• Density: 1.04
• Vapor Pressure: 0.00139mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 1H-Benzimidazole,1-butyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,1-butyl-(9CI)(4886-30-0)
• EPA Substance Registry System: 1H-Benzimidazole,1-butyl-(9CI)(4886-30-0)

Safety Data

• Hazardous Substances Data: 4886-30-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1H-Benzimidazole,1-butyl-(9CI) is utilized as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1H-Benzimidazole,1-butyl-(9CI) serves as a starting material or a scaffold for the development of new drugs. Its potential biological activities, such as antimicrobial, anti-inflammatory, or anticancer properties, make it an attractive candidate for drug discovery and optimization. Researchers can modify its structure to explore its therapeutic potential and improve its pharmacological properties.
Used in Chemical Research:
1H-Benzimidazole,1-butyl-(9CI) is also employed in chemical research to study the reactivity and properties of benzimidazole derivatives. Understanding its chemical behavior can provide insights into the development of new synthetic methods, catalysts, or ligands for various applications in the chemical industry.

InChI:InChI=1/C11H14N2/c1-2-3-8-13-9-12-10-6-4-5-7-11(10)13/h4-7,9H,2-3,8H2,1H3

Upstream product

• 51-17-2 benzoimidazole 
• 696-62-8 para-iodoanisole 
• 429-41-4 tetrabutyl ammonium fluoride 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 1384164-83-3 1-(2,3,4,5,6-pentamethylbenzyl)-3-(n-butyl)-benzimidazolium chloride 
• 1384164-85-5 1-(n-butyl)-3-(3,4,5-trimethoxybenzyl)benzimidazolium chloride 
• 1610951-59-1 (1-butyl-2-diphenylphosphino-3-methylbenzoimidazolium)chlorogold(I) triflate 
• 1415396-57-4 C₂₃H₂₃N₂O₂⁽¹⁺⁾*I^(1-) 
• 1401430-13-4 C₁₈H₁₉BrI₂N₂Te 
• 1401430-11-2 C₁₈H₁₉BrI₂N₂Se 
• 1401430-09-8 C₁₈H₁₉Br₃N₂Se 
• 1401430-04-3 C₁₈H₁₉BrN₂Te 
• 1401430-02-1 C₁₈H₁₉BrN₂Se 
• 1401429-99-9 C₁₈H₁₉BrN₂S 
• 1218756-12-7 3-(2-bromobenzyl)-1-butyl-1H-benzo[d]imidazol-3-ium bromide 

Relevant articles and documents

TBAF-assisted copper-catalyzed N-arylation and benzylation of benzazoles with aryl and benzyl halides under the ligand/base/ solvent-free conditions

(Equation Presented) TBAF-assisted N-arylation and benzylation of benzazoles such as 1H-benzimidazole, 1H-indole, and 1H-benzotriazole with aryl and benzyl halides have been demonstrated under the ligand/base/solvent-free conditions. In the presence of CuBr2 and TBAF (n-Bu4NF), the azoles underwent N-arylation and benzylation with aryl and benzyl halides smoothly in moderate to good yields. It is noteworthy that the reaction is conducted under the ligand/base/solvent-free conditions.

Reduction of the isolated double bond in bis(N- alkenylhenzimidazole)Pd(II) complexes with KBH4

Palladium(II)-promoted vicinal diamination of N-alkenylbenzimidazoles has been investigated. Dichlorobis(1(alkenyl)benzimidazole)palladium(II) complexes were identified as initial reaction products which proved to be rather inert to the subsequent oxidati