495-08-9

Basic information

• Product Name: 2,5-dihydroxybenzyl alcohol
• Synonyms: 2,5-dihydroxybenzyl alcohol;2,5-Dihydroxybenzyl alcohol, Hydroxymethyl-hydrochinone;Gentisyl alcohol;2-(Hydroxymethyl)-1,4-benzenediol;2-Hydroxymethyl-1,4-benzenediol;3,6-Dihydroxybenzenemethanol;Salirepol;1,4-Benzenediol, 2-(hydroxyMethyl)-
• CAS NO: 495-08-9
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 140.14
• Mol File: 495-08-9.mol
• Article Data: 15

Chemical Properties

• Melting Point: 100°
• Boiling Point: 216.62°C (rough estimate)
• Flash Point: 152.6°C
• Appearance: /
• Density: 1.2127 (rough estimate)
• Vapor Pressure: 0.00065mmHg at 25°C
• Refractive Index: 1.4638 (estimate)
• PKA: 10.46±0.18(Predicted)
• CAS DataBase Reference: 2,5-dihydroxybenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dihydroxybenzyl alcohol(495-08-9)
• EPA Substance Registry System: 2,5-dihydroxybenzyl alcohol(495-08-9)

Safety Data

• Hazardous Substances Data: 495-08-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 97, p. 5272, 1975 DOI: 10.1021/ja00851a042

Purification Methods

Crystallise the alcohol from ligroin, CHCl3, AcOH or H2O. Sublime it at ~70o under high vacuum. [Beilstein 6 II 1084, 6 III 6326.]

InChI:InChI=1/C7H8O3/c8-4-5-3-6(9)1-2-7(5)10/h1-3,8-10H,4H2

Upstream product

• 644-17-7 2-hydroxymethyl-1,4-benzoquinone 
• 1447933-44-9 2-(2-bromomethyl-4-methoxyphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 27060-75-9 4-bromo-3-methylanisole 
• 41951-76-2 2-hydroxy-5-methoxybenzyl alcohol 
• 33524-31-1 2,5-dimethoxybenzyl alcohol 
• 150-76-5 4-methoxy-phenol 
• 1250873-78-9 (2,5-dihydroxy-1-phenyl)methyltrimethylammonium iodide 
• 1250873-77-8 2-(ethoxymethyl)benzene-1,4-diol 
• 1250873-75-6 4-hydroxy-6-methylene-2,4-cyclohexadien-1-one 
• 123-31-9 hydroquinone 
• 1194-98-5 2,5-Dihydroxybenzaldehyde 
• 50-00-0 formaldehyd 

Downstream Products

• 33524-31-1 2,5-dimethoxybenzyl alcohol 
• 95-71-6 2-methylbenzene-1,4-diol 
• 1250873-77-8 2-(ethoxymethyl)benzene-1,4-diol 
• 1250873-75-6 4-hydroxy-6-methylene-2,4-cyclohexadien-1-one 
• 553-97-9 2-Methyl-1,4-benzoquinone 
• 114480-36-3 2,5-bis(4-n-butoxybenzoyloxy)benzyl alcohol 
• 114480-35-2 2,5-bis(4-ethoxybenzoyloxy)benzyl alcohol 
• 105252-91-3 2,5-bis[(4'-(methoxy)benzoyl)oxy]benzyl alcohol 
• 1194-98-5 2,5-Dihydroxybenzaldehyde 
• 1227628-39-8 C₁₁H₁₅IO₄ 
• 40931-12-2 (2,5-Bis-methoxymethoxy-phenyl)-methanol 

Relevant articles and documents

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The invention belongs to the field of medical synthesis, in particular relates to a supple red alkone epirubicin than star intermediate chemical synthesis method. The invention relates to 2, 5 - dihydroxy benzyl alcohol as the raw material synthetic suppl

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The invention belongs to the field of medicine synthesis and particularly provides a daunomycinone intermediate compound. Daunomycinone can be purely chemically synthesized by adoption of the intermediate compound. By adoption of 2,5-dyhydroxylbenzyl alco

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