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8-Chloroquinolin-6-amine is a chemical compound characterized by a quinoline ring with a chlorine atom at the eighth position and an amine group at the sixth position. It is recognized for its potential biological activities and medical applications, particularly in the realms of anti-malarial and anti-cancer research. Its unique structure and reactivity render it a valuable intermediate in the synthesis of pharmaceuticals and other organic compounds, underlining its significance in organic chemistry and pharmaceutical science.

50358-62-8

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50358-62-8 Usage

Uses

Used in Pharmaceutical Synthesis:
8-Chloroquinolin-6-amine is utilized as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and reactivity make it a key building block for the development of new drugs and molecules.
Used in Organic Chemistry Research:
In the field of organic chemistry, 8-chloroquinolin-6-amine is employed for research into its potential reactivity and the synthesis of novel compounds, contributing to the advancement of chemical knowledge and the discovery of new chemical entities.
Used in Anti-Malarial Applications:
8-Chloroquinolin-6-amine is explored for its anti-malarial properties, with research focusing on its potential to combat malaria, a disease affecting millions worldwide. Its unique chemical structure may offer new avenues for the development of effective anti-malarial drugs.
Used in Anti-Cancer Applications:
8-CHLOROQUINOLIN-6-AMINE is also under investigation for its anti-cancer properties, with studies aiming to understand its potential to inhibit the growth and proliferation of cancer cells. The exploration of 8-chloroquinolin-6-amine in this context could lead to the creation of new cancer therapeutics.
Used in Drug Development:
8-Chloroquinolin-6-amine is used in drug development as a precursor to potentially active pharmaceutical ingredients, with the goal of creating new medications that can address various health conditions more effectively.

Check Digit Verification of cas no

The CAS Registry Mumber 50358-62-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,5 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50358-62:
(7*5)+(6*0)+(5*3)+(4*5)+(3*8)+(2*6)+(1*2)=108
108 % 10 = 8
So 50358-62-8 is a valid CAS Registry Number.

50358-62-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-chloroquinolin-6-amine

1.2 Other means of identification

Product number -
Other names 6-Quinolinamine, 8-chloro-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50358-62-8 SDS

50358-62-8Relevant articles and documents

Synthesis of mono-substituted derivatives of 6-aminoquinoline

Lan, Tian,Yuan, Xian Xia,Yu, Jiang Hong,Jia, Chao,Wang, Yu Shi,Zhang, Hui Juan,Ma, Zi Feng,Ye, Wei Dong

, p. 253 - 255 (2012/01/04)

Several 6-aminoquinoline derivatives, which could be used in drug design, have been synthesized. The reaction conditions were comparatively studied, and the p-chloroaniline was used as optimum oxidant in Skraup-Doebner-Von Miller reaction. The nitro group was reduced effectively by SnCl2 with no halo-removed occurred.

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