50398-09-9

Basic information

• Product Name: Piperazine, 1-methyl-, monohydrochloride
• CAS NO: 50398-09-9
• Molecular Formula: C5H12N2.ClH
• Molecular Weight: 173.086
• Mol File: 50398-09-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-methyl-, monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-methyl-, monohydrochloride(50398-09-9)
• EPA Substance Registry System: Piperazine, 1-methyl-, monohydrochloride(50398-09-9)

Safety Data

• Hazardous Substances Data: 50398-09-9(Hazardous Substances Data)

Upstream product

• 7647-01-0 hydrogenchloride 
• 62226-74-8 1-benzyl-4-methylpiperazine 
• 109-01-3 1-methyl-piperazine 
• 5625-52-5 1-methylpiperazin-2,5-dione 
• 93378-54-2 1-methyl-4-(2-tetrahydro-1,3-diazepinylthioacetyl)piperazine dihydrochloride 
• 93378-52-0 1-methyl-4-(2-tetrahydropyrimidinylthioacetyl)piperazine dihydrochloride 
• 2055-46-1 3,4,5,6-tetrahydropyrimidine-2-thione 
• 42951-91-7 2-chloro-1-(4-methylpiperazin-1-yl)ethan-1-one hydrochloride 

Downstream Products

• 60868-01-1 3-(4-methylpiperazin-1-yl)-1-phenylpropan-1-one 
• 100316-89-0 3-(4-methyl-piperazino)-1-[2]thienyl-propan-1-one 
• 18413-26-8 4-methylpiperazin-1-yl-biguanidine dihydrochloride 
• 83808-21-3 2-(4-methyl-1-piperazinyl)acetamide 
• 75956-17-1 2-Methyl-6-[2-(4-methyl-piperazin-1-yl)-ethyl]-4-o-tolyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 133297-00-4 1-(4-methyl-piperazino)-3-phenyl-pentan-3-ol 
• 132539-06-1 zyprexa 
• 38029-90-2 2-(4-Methyl-1-piperazinyl)-pyridin-5-sulfonamid 

Relevant articles and documents

Highly chemoselective Pd-C catalytic hydrodechlorination leading to the highly efficient N-debenzylation of benzylamines

(Equation Presented) In the presence of 1,1,2-trichloroethane, a novel procedure for the Pd-C catalytic N-debenzylation of benzylamines was established. The method proceeded in a synergistic catalytic system and directly gave the products as crystal amine hydrochlorides in practically quantitative yields.

Modular syntheses of multidentate ligands with variable N-donors: Applications to tri- and tetracopper(i) complexes

A general method for the preparation of multidentate ligands comprised of a multi-imine platform derived from 1,1,1-tris(aminomethyl)ethane or tris(aminoethyl)amine connected to bi- and tridentate N-donor chelates has been developed. The feasibility of the method has been demonstrated through the synthesis and characterization of a large set of these ligand types. Complexation to Cu(i) was accomplished for several cases, yielding tri- and tetracopper(i) complexes that have been characterized in solution by NMR spectroscopy and conductivity, and in the solid state by elemental analysis, mass spectrometry, and/or X-ray crystallography. These complexes are potentially useful for modeling multicopper protein active sites. The Royal Society of Chemistry.

Isotopically enriched N-substituted piperazines and methods for the preparation thereof

In some embodiments, this invention pertains to isotopically enriched N-substituted piperazines. In some embodiments, this invention pertains to methods for the preparation of isotopically enriched N-substituted piperazines.