50402-83-0

Basic information

• Product Name: (7-METHYL-2-OXO-2H-CHROMEN-4-YL)ACETIC ACID
• Synonyms: (7-METHYL-2-OXO-2H-CHROMEN-4-YL)ACETIC ACID;IFLAB-BB F1083-0010;(7-methyl-2-oxo-2H-chromen-4-yl)acetic acid(SALTDATA: FREE);2-(7-methyl-2-oxo-2H-chromen-4-yl)acetic acid
• CAS NO: 50402-83-0
• Molecular Formula: C₁₂H₁₀O₄
• Molecular Weight: 218.21
• Mol File: 50402-83-0.mol
• Article Data: 11

Chemical Properties

• Melting Point: 190 °C
• Boiling Point: 448.7°C at 760 mmHg
• Flash Point: 180.5°C
• Appearance: /
• Density: 1.334g/cm³
• Vapor Pressure: 7.75E-09mmHg at 25°C
• Refractive Index: 1.593
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• PKA: 4.34±0.10(Predicted)
• CAS DataBase Reference: (7-METHYL-2-OXO-2H-CHROMEN-4-YL)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (7-METHYL-2-OXO-2H-CHROMEN-4-YL)ACETIC ACID(50402-83-0)
• EPA Substance Registry System: (7-METHYL-2-OXO-2H-CHROMEN-4-YL)ACETIC ACID(50402-83-0)

Safety Data

• Statements: 41
• Safety Statements: 39
• Hazardous Substances Data: 50402-83-0(Hazardous Substances Data)

Usage

General Description

(7-Methyl-2-oxo-2H-chromen-4-yl)acetic acid, also known as coumarin-3-carboxylic acid, is a chemical compound belonging to the coumarin family. It is a synthetic derivative of coumarin, a natural compound found in many plants. (7-METHYL-2-OXO-2H-CHROMEN-4-YL)ACETIC ACID has been studied for its potential as an anti-inflammatory and antioxidant agent, as well as for its therapeutic potential in the treatment of various diseases. Additionally, it has been investigated for its role in the synthesis of pharmaceuticals and agrochemicals. The structural characteristics and chemical properties of (7-Methyl-2-oxo-2H-chromen-4-yl)acetic acid make it a valuable compound for scientific research and potential applications in various fields.

InChI:InChI=1/C12H10O4/c1-7-2-3-9-8(5-11(13)14)6-12(15)16-10(9)4-7/h2-4,6H,5H2,1H3,(H,13,14)

Upstream product

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Downstream Products

• 109614-27-9 4-(4-methoxy-trans-styryl)-7-methyl-coumarin 
• 1592737-89-7 (E)-7-methyl-4-[2-[2-(2-propyn-1-yloxyl)phenyl]ethenyl]-2H-1-benzopyran-2-one 
• 14002-90-5 4,7-dimethyl-coumarin 
• 119249-24-0 11-(2-methoxy-phenyl)-7-methyl-2-phenyl-3a,3b,11,11a-tetrahydro-chromeno[3,4-e]isoindole-1,3,4-trione 
• 116535-27-4 4-(2-hydroxy-4-methyl-phenyl)-6-(2-methoxy-phenyl)-cyclohex-4-ene-1,2,3-tricarboxylic acid-1,2-anhydride-3-lactone 
• 142009-39-0 9-(4-hydroxy-phenyl)-3-methyl-6-oxo-6a,7,8,9-tetrahydro-6H-benzo[c]chromene-7,8-dicarboxylic acid-anhydride 
• 50402-86-3 4-[2-(2,4-dinitro-phenylhydrazono)-propyl]-7-methyl-coumarin 
• 41295-51-6 4-(chloromethyl)-7-methyl-2H-chromen-2-one 
• 15719-64-9 methylammonium carbonate 
• 109614-91-7 4-(2-methoxy-trans-styryl)-7-methyl-coumarin 

Relevant articles and documents

Regiospecific inverse electron demand Diels-Alder reactions of 7-methylcoumarin-4-azadienes

Condensation of 7-methylcoumarin-4-carbaldehyde with different anilines affords 7-methylcoumarin-4-azadienes. The 7-methylcoumarin-4-azadienes do not undergo normal electron demand Diels-Alder reaction with N-phenylmaleimide, but react with dihydropyran, dihydrofuran, and styrene via inverse electron demand Diels-Alder reaction in the presence of anhydrous ZnCl2. The diene involves the azomethine group and the aniline ring. The product is a mixture of two diastereomers in which the major diastereomer has all the hydrogens at the ring junction in cis configuration. This journal is

Synthetic and Structural Studies on Novel 4,3′-Bicoumarins

A series of directly linked 4-3′ bicoumarins have been synthesized by both Knoevenagel and Perkin reactions. This single-step transformation was accomplished by the reaction of coumarin-4-acetates with substituted salicylaldehydes in presence of piperidin

Facile intramolecular Diels-Alder reaction of 4-(o-propargyloxy) styrylcoumarins leading to highly fluorescent coumarin-containing polycyclic compounds

The 4-(o-propargyloxy)styrylcoumarins are prepared by the condensation of O-propargylated salicylaldehyde with substituted coumarin-4-acetic acids. The intramolecular Diels-Alder reaction of 4-(o-propargyloxy)styrylcoumarins, without any catalyst gives fu