5058-01-5

Basic information

• Product Name: 2,5-dihydroxyvaleric acid delta lactone
• Synonyms: 2,5-dihydroxyvaleric acid delta lactone;3-Hydroxytetrahydro-2H-pyran-2-one;3-hydroxyoxan-2-one
• CAS NO: 5058-01-5
• Molecular Formula: C5H8O3
• Molecular Weight: 116.11522
• Mol File: 5058-01-5.mol

Chemical Properties

• Boiling Point: 266°Cat760mmHg
• Flash Point: 126.4°C
• Appearance: /
• Density: 1.276g/cm³
• Vapor Pressure: 0.00122mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: 2,5-dihydroxyvaleric acid delta lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dihydroxyvaleric acid delta lactone(5058-01-5)
• EPA Substance Registry System: 2,5-dihydroxyvaleric acid delta lactone(5058-01-5)

Safety Data

• Hazardous Substances Data: 5058-01-5(Hazardous Substances Data)

Usage

General Description

2,5-dihydroxyvaleric acid delta lactone, also known as g-dodecalactone, is a colorless or pale yellow liquid with a sweet, creamy, coconut-like odor. It is commonly used in the food and cosmetic industries as a flavoring agent and fragrance ingredient, adding a sweet and fruity aroma to products. This chemical is a lactone, which means it contains a cyclic ester group, and its pleasant scent makes it a popular choice for use in perfumes, lotions, and other scented products. Additionally, 2,5-dihydroxyvaleric acid delta lactone has been studied for its potential health benefits, including its antioxidant properties and its potential as an anti-cancer agent.

InChI:InChI=1/C5H8O3/c6-4-2-1-3-8-5(4)7/h4,6H,1-3H2

Upstream product

• 55974-69-1 α-bromo-δ-valerolactone 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 861590-89-8 diethyl 2-bromo-2-(3-chloropropyl)malonate 
• 70-26-8 2,5-diaminopentanoic acid 

Relevant articles and documents

A 2,5-di-hydroxy valeric acid DELTA lactone synthetic method

The invention aims to provide a synthesizing method of 2,5-dihydroxyvaleric acid delta lactone. The synthesizing method comprises an improved and economical method for synthesizing lactone derivatives and the like. Importantly, the synthesizing method is suitable for high-selectivity low-cost mass production.

Aluminium(III) Coordination to Hydroxy Carboxylates: the Influence of Hydroxy Substituents Enabling Tridentate Binding

Potentiometric evalution of the interaction between aluminium(III) and the hydroxy carboxylates 3-deoxy-D-ribo-hexonate (L1H) and 2,5-dihydroxypentanoate (L2H) provided evidence for the formation of 1:1 complexes only, though with the ligand being present in singly, doubly and quadruply deprotonated forms in the hexonate complexes, and in singly, doubly and triply deprotonated forms in those of the pentanoate.At 298 K in aqueous media, I = 0.1 (NaCl), equilibrium quotient values obtained through use of the programs PKAS and BEST were: -log(1)->+>/1H>) (or pKa(L1H)) = 3.58+/-0.03; log(1)2+>/3+>1)->) = 1.97+/-0.03; log(-1L1)+>+>/1)2+>) = -2.83+/-0.05; log(-3L1)->+>2/-1L1)+>) = -9.17+/-0.08; -log(2)->+>(2H>) (or pKa(L2H)) = 3.92+/-0.03; log(2)2+>/3+>2)->) = 2-04+/-0.03; log(-1L2)+>+>/2)2+>) = -3.14+/-0.06; log(-2L2>+>/-1L2)+>) = -2.25+/-0.09.The very close similarity of the results for 3-deoxy-D-ribo-hexonate (3-deoxygluconate) and those known for D(+)-gluconate has led to the suggestion that the complexes of the quadruply deprotonated ligands may involve trialkoxo coordination through the C1, C5 and C6 substituents.

Hydrogenation process for the formation of 3,5-dihydro HMG-CoA reductase inhibitors

A novel hydrogenation process, using a homogenous iridium or rhodium catalyst for selectively adding hydrogen to the 3,5 positions in the polyhydronaphthyl ring of lovastatin, simvastatin or C-8-acyl or C-6-substituted analogs thereof, is disclosed.