50609-85-3

Basic information

• Product Name: 2-Propene-1-thione, 3-(methylamino)-3-(methylthio)-1-phenyl-
• CAS NO: 50609-85-3
• Molecular Formula: C11H13NS2
• Molecular Weight: 223.363
• Mol File: 50609-85-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Propene-1-thione, 3-(methylamino)-3-(methylthio)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propene-1-thione, 3-(methylamino)-3-(methylthio)-1-phenyl-(50609-85-3)
• EPA Substance Registry System: 2-Propene-1-thione, 3-(methylamino)-3-(methylthio)-1-phenyl-(50609-85-3)

Safety Data

• Hazardous Substances Data: 50609-85-3(Hazardous Substances Data)

Upstream product

• 4849-59-6 5-phenyl-3-methylthio-1,2-dithiolium iodide 
• 30162-68-6 2-methyl-5-phenyl-4-isothiazolin-3-thione 
• 13636-88-9 3,3-bis(methylthio)-1-phenylprop-2-en-1-one 
• 18712-05-5 2-methyl-3-methylthio-5-phenylisothiazolium iodide 
• 100-46-9 benzylamine 
• 91787-80-3 3-methylamino-3-methylthio-1-phenylprop-2-en-1-one 

Downstream Products

• 478028-07-8 methyl 3-(methylamino)-5-phenylthiophene-2-carboxylate 
• 24437-54-5 1‐(4‐methylphenyl)‐2‐(methylsulfanyl)ethanone 
• 7633-38-7 di-tert-butyl fumarate 
• 213180-58-6 1-(3-Methylamino-5-phenyl-thiophen-2-yl)-ethanone 
• 92802-07-8 ethyl 3-(methylamino)-5-phenylthiophene-2-carboxylate 
• 50609-80-8 2-benzoyl-3-methylamino-5-phenylthiophene 
• 213180-70-2 2-ethoxycarbonyl-2-methanesulfonyl-3-methylamino-5-phenyl-2,3-dihydrothiophene 

Relevant articles and documents

Facile synthesis of 4-alkyl (and aryl)-2-aryl-6-diazo-4H-thieno[3,2-b] pyridine-5,7-diones

Treatment of 3-{3-alkyl (and aryl)amino-5-arylthieno-2-yl}-2-diazo-3- oxopropanoates 8 with TMSOTf (3 equiv) in the presence of Et3N (6 equiv) in CH2Cl2 for 1 h at room temperature afforded 4-alkyl (and aryl)-2-aryl-6-diazo-4H-thieno

A facile and convenient synthesis of 3-alkylamino-5-arylthiophenes with a variety of substituents at C-2 and studies of reaction mechanisms

Thioaroylketene S,N-acetals were treated with active methylene compounds including β-keto ester, nitromethane, cyanoacetic acid, p- toluenesulfonylacetone, 4-nitrophenylacetic acid, and diethyl (2- oxopropyl)phosphonate in the presence of mercury(II) acetate in CH2Cl2 at room temperature. These reactions gave 3-alkylamino-5-arylthiophenes containing various substituents, which comprised, respectively, alkoxycarbonyl, nitro, cyano, p-toluenesulfonyl, 4-nitrophenyl, and diethylphosphono groups at C-2 in good yields. The reaction of 3-methylamino- 3-methylthio-1-phenylthioxopropene with malonic acid or Meldrum's acid under the same conditions gave 3-methylamino-5-phenylthiophene. Similarly, treatment of 3-methylamino-3-methylthio-1-phenylthioxopropene with various enolizable cyclic ketones such as 4-hydroxy-6-methyl-2-pyrone, homophthalic anhydride, 2-hydroxy1,4-benzoquinone, and 1,3-diethyl-2-thiobarbituric acid gave thieno[3,2-b]pyridin-4-one, thieno[3,2c]isoquinolin-5-one, thieno[3,2- c]benzazepine-1,6-dione, and thieno[3,2-d]pyrimidine-2,4-dione, respectively.