508237-23-8

Basic information

• Product Name: 5-(3,4-Dimethoxybenzylamino)-2-(2-furyl)-8-(5-methoxyisoindolin-2-ylmethyl)[1,2,4]triazolo[1,5-c]pyrimidine
• CAS NO: 508237-23-8
• Molecular Weight: 512.568
• Mol File: 508237-23-8.mol

Chemical Properties

• CAS DataBase Reference: 5-(3,4-Dimethoxybenzylamino)-2-(2-furyl)-8-(5-methoxyisoindolin-2-ylmethyl)[1,2,4]triazolo[1,5-c]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3,4-Dimethoxybenzylamino)-2-(2-furyl)-8-(5-methoxyisoindolin-2-ylmethyl)[1,2,4]triazolo[1,5-c]pyrimidine(508237-23-8)
• EPA Substance Registry System: 5-(3,4-Dimethoxybenzylamino)-2-(2-furyl)-8-(5-methoxyisoindolin-2-ylmethyl)[1,2,4]triazolo[1,5-c]pyrimidine(508237-23-8)

Safety Data

• Hazardous Substances Data: 508237-23-8(Hazardous Substances Data)

Upstream product

• 213896-16-3 5-(3,4-Dimethoxybenzylamino)-8-formyl-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]pyrimidine 
• 127168-88-1 5-methoxy-2,3-dihydro-1H-isoindole 

Relevant articles and documents

Receptor Antagonists

The present invention provides an α2c-adrenoceptor antagonist comprising, as an active ingredient, a condensed-ring-pyrimidine derivative represented by general formula (I) below or a pharmaceutically acceptable salt thereof useful for treating and/or preventing various diseases induced by hyperactivity of α2c-adrenoceptor (for example, Parkinson's disease, L-DOPA-induced dyskinesia, tardive dyskinesia and depression) and the like. {wherein p represents an integer of 1 to 3; R1 represents a substituted or unsubstituted heterocyclic group, substituted or unsubstituted aryl, or the like; R2 represents —N(—R4)(—R5) (wherein R4 and R5 are the same or different, and each represents a hydrogen atom, substituted or unsubstituted aralkyl, or the like, or R4 and R5 form a substituted or unsubstituted heterocyclic group together with the adjacent nitrogen atom) or the like; and -Q- represents —N═C(—R7)— [wherein R7 represents —N(—R9)(—R10) (wherein R9 and R10 are the same or different, and each represents substituted or unsubstituted aralkyl, or the like, or R9 and R10 form a substituted or unsubstituted heterocyclic group together with the adjacent nitrogen atom) or the like] or the like}