51114-70-6

Basic information

• Product Name: 1(2H)-Naphthalenone, 2,2-dibromo-3,4-dihydro-
• Synonyms: 1(2H)-Naphthalenone, 2,2-dibromo-3,4-dihydro-;2,2-dibromo-3,4-dihydronaphthalen-1-one;2,2-DIBROMO-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE（WS203732）
• CAS NO: 51114-70-6
• Molecular Formula: C₁₀H₈Br₂O
• Molecular Weight: 303.97792
• EINECS: -0
• Mol File: 51114-70-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 330.2°C at 760 mmHg
• Flash Point: 109.8°C
• Appearance: /
• Density: 1.9g/cm³
• Vapor Pressure: 0.000169mmHg at 25°C
• Refractive Index: 1.654
• CAS DataBase Reference: 1(2H)-Naphthalenone, 2,2-dibromo-3,4-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Naphthalenone, 2,2-dibromo-3,4-dihydro-(51114-70-6)
• EPA Substance Registry System: 1(2H)-Naphthalenone, 2,2-dibromo-3,4-dihydro-(51114-70-6)

Safety Data

• Hazardous Substances Data: 51114-70-6(Hazardous Substances Data)

Usage

General Description

1(2H)-Naphthalenone, 2,2-dibromo-3,4-dihydro- is a chemical compound with the molecular formula C10H6Br2O. It is a yellow solid with a strong odor, and is typically used in the synthesis of pharmaceuticals and other organic compounds. It is also used as an intermediate in the manufacture of dyes and other chemicals. 1(2H)-Naphthalenone, 2,2-dibromo-3,4-dihydro- is known to be toxic to aquatic organisms and may cause long-term adverse effects in the aquatic environment. It is important to handle and dispose of this chemical with care to minimize its impact on the environment.

InChI:InChI=1/C10H8Br2O/c11-10(12)6-5-7-3-1-2-4-8(7)9(10)13/h1-4H,5-6H2

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 3349-64-2 1-tetralone oxime 
• 447-53-0 1,2-Dihydronaphthalene 

Downstream Products

• 90-15-3 α-naphthol 
• 771-15-3 2-bromo-1-naphthol 
• 1056246-70-8 2-bromo-1-tetralone 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 1240493-84-8 2,3:8,9-dibenzo-12-phenyldispiro[4.0.5.1]dodeca-2,8-diene-1,4,7-trione 

Relevant articles and documents

N-Methylpyrrolidin-2-one hydrotribromide (MPHT) a mild reagent for selective bromination of carbonyl compounds: Synthesis of substituted 2-bromo-1-naphtols

The reaction of the N-methylpyrrolidin-2-one hydrotribromide complex (MPHT) with substituted-1-tetralones has been investigated. This safety reagent proved to be successful for selective α,α-dibromination of tetralones. Moreover, under base-free conditions, several 2-bromo-1-naphtols were obtained from tetralones in a 'one pot' sequence in good to excellent yields.

One-pot syntheses of α,α-dibromoacetophenones from aromatic alkenes with 1,3-dibromo-5,5-dimethylhydantoin

A novel method for the preparation of α,α-dibromoacetophenones from aromatic alkenes was reported. This procedure was mediated by 1,3-dibromo-5,5-dimethylhydantoin, which served as bifunctional reagent, proceeding oxidation and bromination in one-pot.

Visible-light photoredox catalysis: Dehalogenation of vicinal dibromo-, α-halo-, and α,α-dibromocarbonyl compounds

vic-Dibromo-, α-halo-, or α,α-dibromocarbonyl compounds can be efficiently dehalogenated using catalytic tris(2,2′-bipyridyl) ruthenium dichloride (Ru(bpy)3Cl2) in combination with 1,5-dimethoxynaphthalene (DMN) and ascorbate as sacrificial electron donor. For this process, a visible light promoted photocatalytic cycle is proposed that involves the reduction of carbon halogen bonds via free radical intermediates.