51290-78-9

Basic information

• Product Name: 4-(benzylsulfanyl)pyridine
• Synonyms: 4-(Benzylsulfanyl)pyridine; 4-(Benzylthio)-pyridine; pyridine, 4-[(phenylmethyl)thio]-
• CAS NO: 51290-78-9
• Molecular Formula: C₁₂H₁₁NS
• Molecular Weight: 201.2874
• Mol File: 51290-78-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 337.4°C at 760 mmHg
• Flash Point: 157.9°C
• Density: 1.15g/cm³
• Vapor Pressure: 0.000205mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 4-(benzylsulfanyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzylsulfanyl)pyridine(51290-78-9)
• EPA Substance Registry System: 4-(benzylsulfanyl)pyridine(51290-78-9)

Safety Data

• Hazardous Substances Data: 51290-78-9(Hazardous Substances Data)

Upstream product

• 4556-23-4 pyridine-4-thiol 
• 100-51-6 benzyl alcohol 
• 626-61-9 4-Chloropyridine 
• 19524-06-2 4-bromopyridine hydrochloride 
• 100-39-0 benzyl bromide 
• 66134-95-0 pyridyl-4-thiolate sodium salt 
• 100-53-8 phenylmethanethiol 
• 78526-32-6 2,6-Dimethyl-4'-p-tolylsulfanyl-4'H-[1,1']bipyridinyl-4-one 
• 71831-63-5 4'-Benzylsulfanyl-2,6-dimethyl-4'H-[1,1']bipyridinyl-4-one 
• 78526-43-9 4'-Benzylsulfanyl-2-methyl-4'H-[1,1']bipyridinyl-4-one 
• 78526-40-6 4'-Benzylsulfanyl-4'H-[1,1']bipyridinyl-4-one 
• 5421-92-1 1-(4-pyridyl)pyridinium chloride hydrochloride 
• 100-44-7 benzyl chloride 
• 19829-29-9 4-pyridinethione 

Downstream Products

• 89818-48-4 4-[(phenylmethyl)sulfinyl]pyridine 
• 101736-20-3 4-[(phenylmethyl)sulfonyl]pyridine 

Relevant articles and documents

Promoting Effect of Crystal Water Leading to Catalyst-Free Synthesis of Heteroaryl Thioether from Heteroaryl Chloride, Sodium Thiosulfate Pentahydrate, and Alcohol

It is observed the crystal water in sodium thiosulfate pentahydrate (Na2S2O3·5H2O) can promote its multicomponent reaction with heteroaryl chlorides and alcohols, providing a facile, green, and specific synthesis of unsymmetrical heteroaryl thioethers via one-step formation of two C-S bonds under catalyst-, additive-, and solvent-free conditions. Mechanistic studies suggest that the crystal water in Na2S2O3·5H2O is crucial in generating the key thiol intermediates and byproduct NaHSO4, which then catalyzes the dehydrative substitution of alcohols with thiols to afford thioethers.

Copper-Catalyzed Aerobic Formation of Unstable Sulfinyl Radicals for the Synthesis of Sulfinates and Thiosulfonates

Copper-catalyzed aerobic coupling of thiols and alcohols affords sulfinates and thiosulfonates. These products are assumed to form via sulfinyl radicals which are not commonly found in oxidative coupling reactions of thiols. A reaction mechanism involving sulfinyl radicals is proposed, and mass and electron paramagnetic resonance (EPR) experimental results are provided.

Hybrid molecules of estrone: New compounds with potential antibacterial, antifungal, and antiproliferative activities

New hybrid molecules of estrone were synthesized as compounds indicating promising biological activity (antibacterial, antimycobacterial, antifungal, and antiproliferative). The prepared molecules contained various heterocyclic units (pyridine, benzylsulf