513-42-8

Basic information

• Product Name: Methallyl alcohol
• Synonyms: 3-Hydroxy-2-methylpropene;beta-methylallylalcohol;CH2=C(CH3)CH2OH;methacrylalcohol;METHALLYL ALCOHOL;ISOPROPENYLCARBINOL;'ISOBUTENOL';BETA-METHALLYL ALCOHOL
• CAS NO: 513-42-8
• Molecular Formula: C₄H₈O
• Molecular Weight: 72.11
• EINECS: 208-161-0
• Product Categories: Industrial/Fine Chemicals;Acyclic;Alkenes;Building Blocks;Chemical Synthesis;Organic Building Blocks;CONSTRUCTION
• Mol File: 513-42-8.mol
• Article Data: 71

Chemical Properties

• Melting Point: -50 °C
• Boiling Point: 113-115 °C(lit.)
• Flash Point: 92 °F
• Appearance: clear colourless liquid
• Density: 0.857 g/mL at 25 °C(lit.)
• Vapor Pressure: 9.15mmHg at 25°C
• Refractive Index: n20/D 1.426(lit.)
• Storage Temp.: Flammables area
• PKA: 14.49±0.10(Predicted)
• Water Solubility: 11 g/100 mL
• BRN: 969226
• CAS DataBase Reference: Methallyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: Methallyl alcohol(513-42-8)
• EPA Substance Registry System: Methallyl alcohol(513-42-8)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36-37/39-16
• RIDADR: UN 2614 3/PG 3
• WGK Germany: 3
• RTECS: UD5250000
• TSCA: Yes
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 513-42-8(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

2-Methyl-2-propen-1-ol (MePro) attaches to hemicellulose acetylated galactoglucomannan (AcGGM) backbone providing it with pendant sites that allow subsequent cross-linking and hydrogel formation.

General Description

A colorless liquid with a sharp pungent odor. Soluble in water and floats on water. Moderately toxic by ingestion and is an irritant to eyes and skin. Used in the chemical process industry.

Air & Water Reactions

Highly flammable and soluble in water.

Reactivity Profile

Methallyl alcohol may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas.

Health Hazard

Exposure can cause irritation of eyes, nose and throat.

InChI:InChI=1/C4H8O/c1-4(2)3-5/h5H,1,3H2,2H3

Synthetic route

3-Chloro-2-methylpropene (563-47-3) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With sodium hydrogencarbonate; acrylonitrile; hydroquinone In water at 40 - 67℃; for 5.5h; Reagent/catalyst; Temperature;	99.05%
With t-butylnitrite; water; sodium hydrogencarbonate; acrylonitrile at 45 - 67℃; for 3h; Catalytic behavior; Reagent/catalyst;	99.05%
With 5,5-Dimethyl-1-pyrroline N-oxide; phenyl tert-butylmethyldimethoxysilane; water; sodium acetate; sodium carbonate; acetonitrile at 45 - 67℃; for 2.5h; Catalytic behavior; Reagent/catalyst;	99.02%

2-methylpropenal (78-85-3) + cyclohexanol (108-93-0) → cyclohexanone (108-94-1) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With TEMPOL; SnO2#Nb2O5 at 90℃; under 3000.3 Torr; for 10h; Inert atmosphere;	A 95.33% B n/a

methallyl formate (820-57-5) → formamide (77287-34-4, 77287-35-5, 60100-09-6) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With aluminum oxide; ammonia at 0 - 5℃; Gas phase; Large scale;	A 850 g B 95%

2-methylpropenal (78-85-3) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With hydrogen In water at 70℃; under 11251.1 Torr; for 1.5h; Temperature; Reagent/catalyst; Pressure;	94%
With hydrogen In water at 70℃; under 3000.3 Torr; Temperature; Reagent/catalyst; Pressure;	89%
With sodium tetrahydroborate; pyrographite In tetrahydrofuran; water at 20℃; for 0.0166667h;	85%

sodium acetate (127-09-3) + 3-Chloro-2-methylpropene (563-47-3) → methallyl acetate (820-71-3) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With sodium D-gluconate; copper(II) sulfate In water for 4h; Reagent/catalyst; Reflux;	A 92% B 5.5%

2-methyl-1,2-epoxypropane (558-30-5) → isobutyraldehyde (78-84-2) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
lithium phosphate at 210℃; for 3h; Kinetics; Thermodynamic data; 110 - 180 degC , ΔG, ΔH, E(activ.);	A 5.79% B 85.1%
With hydrogen; lithium phosphate at 210℃; for 3h;	A 5.79% B 85.1%
With 3-chlorobenzoate; methanesulfonic acid In dichloromethane-d2 at 26.5℃; Product distribution; various conc. of methanesulfonic acid in the presence and absence of 3-chlorobenzoic acid;	A 10% B 20%
With 3-chlorobenzoate; methanesulfonic acid In dichloromethane-d2 at 26.5℃;	A 10% B 20%

methacrylic acid methyl ester (80-62-6) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether at -30℃; for 4h; Reduction;	83%
With lithium aluminium tetrahydride In diethyl ether at 0℃; for 1h;	72%

(+/-)-2-Methyl-2,3-oxiranemethanol acetate → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With tellurium; lithium triethylborohydride In tetrahydrofuran for 0.166667h; Ambient temperature;	70%

methanol (67-56-1) + propan-1-ol (71-23-8) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With ZnO/MgZrOx mixed oxide with 4.3 Mg/Zr atomic ratio on MgO nanaosheet at 275℃; Inert atmosphere;	17%

2,5-dimethyl-3,4-dihydro-2H-pyran-2-methanol (54004-34-1) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With aluminum oxide at 500℃;

2-methyl-3-bromo-1-propene (1458-98-6) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With potassium carbonate

isopropenylmethyl ether (628-56-8) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With aluminum oxide; copper(II) sulfate at 225℃; under 760 Torr;

methyl methacrylate (97-63-2) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With lithium aluminium tetrahydride; diethyl ether
With diisobutylaluminium hydride In hexane; dichloromethane at -78℃; for 1.5h; Inert atmosphere;

2-methylpropenal (78-85-3) → 2-methyl-propan-1-ol (78-83-1) + isobutyraldehyde (78-84-2) + acetone (67-64-1) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With magnesium oxide; isopropyl alcohol; boron trioxide at 270℃; other α,β-unsaturated corbonyl compounds, other alcohols;

2-methyl-3-prop-2-enyl phenylselenide (59085-70-0) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With dihydrogen peroxide In pyridine; dichloromethane at 0℃; for 0.333333h; Yield given;

methylmagnesium bromide (75-16-1) + propargyl alcohol (107-19-7) → (Z)-(3-<2H>)-2-methylprop-2-en-1-ol (89732-64-9) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With hydrogenchloride; copper(l) iodide; water-d2 1.) THF, -60 deg C up to RT, 2.) THF, Et2O, H2O, pH=7; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

2-methylpropenal (78-85-3) → 2-methyl-propan-1-ol (78-83-1) + isobutyraldehyde (78-84-2) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With hydrogen; AuZr(O) at 89.9℃; Product distribution; pulse reactor; other temperatures;	A 6.7 % Turnov. B 42.9 % Turnov. C 47.2 % Turnov.

2-chloromethyl-2-methyloxiran (598-09-4) → 1-methylcyclopropanol (29526-99-6) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With magnesium In tetrahydrofuran Heating; Title compound not separated from byproducts;

2-(2-methylallyloxy)tetrahydro-2H-pyran (53250-10-5) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
zeolite HSZ-330 In methanol for 2h; Ambient temperature;

isobutene (115-11-7) + oxygen → 3-methyl-butan-2-one (563-80-4) + acetone (67-64-1) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
at 200 - 240℃; under 58840.6 Torr;

isobutenyl chloride → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With potassium hydroxide
With water; potassium carbonate man destilliert die erhaltene Loesung und Schuettelt das Destillat mit K2CO3, wobei das Isopropenylcarbinol abgeschieden wird, das man ueber CaO entwaessert;

2-methylpropenal (78-85-3) + acetic acid (64-19-7) + zinc → meso-2,5-dimethyl-hexa-1,5-diene-3,4-diol (67470-03-5) + 3-hydroxy-2-methyl-1-propene (513-42-8) + racem-2,5-dimethyl-hexa-1,5-diene-3,4-diol

2-methylpropenal (78-85-3) + diethylzinc (557-20-0) → (R)-3-hydroxy-2-methylpent-1-ene (125637-07-2) + (+)-(R)-2-methylpent-1-en-3-ol (98168-21-9) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With (1R,2S)-(+)-1-cyclohexyl-2-phenyl-2-(N-morpholino)ethanol In hexane; toluene at 20℃; for 3h; Title compound not separated from byproducts.;

2-nitro-2-methylpropanol (76-39-1) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
at 260.4℃; under 49.5 Torr; Kinetics; Further Variations:; Pressures; Temperatures; also in the presence of free radical inhibitors;

methallyl acetate (820-71-3) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
In methanol; potassium hydroxide

3-[(ethoxycarbonyl)oxy]-2-methylpropyl propanoate (1396267-65-4) → propionic acid (802294-64-0) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
at 626.84℃; Kinetics; Further Variations:; Temperatures;

2-methylallyl 1-naphthyl selenide (1073930-96-7) → 2-methylpropenal (78-85-3) + 2-bis[3,5bis(trifluoromethyl)phenyl]diselane (1787-80-0) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With oxygen In n-heptane at 20℃; for 0.25h; Reactivity; Time; UV-irradiation;

Triethyl orthoacetate (78-39-7) + 3-hydroxy-2-methyl-1-propene (513-42-8) → ethyl 4-methyl-4-pentenoate (4911-54-0)

Conditions	Yield
With propionic acid for 8h; Reflux;	100%
With propionic acid at 118℃; for 6h; Johnson orthoester Claisen rearrangement;	98%
With acetic acid at 150 - 170℃; Inert atmosphere;	87%

methanesulfonyl chloride (124-63-0) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 2-methylallyl methanesulfonate (142820-20-0)

Conditions	Yield
With triethylamine In dichloromethane at -15℃; for 1h; Green chemistry;	100%
With triethylamine In tetrahydrofuran for 0.25h; Ambient temperature;
With triethylamine In dichloromethane at -20℃; for 1.5h;
With triethylamine In diethyl ether at -78 - 0℃; Inert atmosphere;

3-hydroxy-2-methyl-1-propene (513-42-8) → 2-methylglycidol (872-30-0)

Conditions	Yield
With tetrabutylphosphonium peroxotantalate; dihydrogen peroxide In water at 0℃; for 3.5h; Schlenk technique; chemoselective reaction;	100%
With C16H36N(1+)*H2NbO5(1-); dihydrogen peroxide In water at 0℃; for 4h; chemoselective reaction;	96.3%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 20℃; for 18h;	83%

4-chlorobenzaldehyde (104-88-1) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 3,3-bis(3-phenyl-2-propen-1-yl)pentane-2,4-dione (106536-22-5) + (E)-1-chloro-4-(3-methylbuta-1,3-dien-1-yl)benzene (106536-23-6) + C18H16

Conditions	Yield
With triphenylphosphine; palladium(II) acetylacetonate In 1,4-dioxane for 50h; Heating;	A 100% B 21% C n/a

p-methoxybenzyl chloride (824-94-2) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 1-((methallyloxy)methyl)-4-methoxybenzene (189366-67-4)

Conditions	Yield
With dmap; triethylamine In dichloromethane at 20℃;	100%
With sodium hydroxide 1.) THF, mineral oil, DMF, 0 deg C, 30 min; 2.) THF, 2 h;	97%
With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide at 0℃; 1.) 30 min, 2.) 2 h;

4-Phenylbutyric acid (1821-12-1) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 2-methyl-2-propen-1-yl 4-phenylbutyrate

Conditions	Yield
With dimesitylammonium pentafluorobenzenesulfonate In n-heptane at 80℃; for 3h;	100%
With Iron(III) isopropoxide; zirconium(IV) tetraisopropoxide In n-heptane for 15h;	99%
dimesitylammonium pentafluorobenzenesulfonate In n-heptane at 80℃; for 3h; Product distribution / selectivity;	99%

[(4-methoxyphenyl)sulfonyl]azanyl sulfamate (1049038-08-5) + 3-hydroxy-2-methyl-1-propene (513-42-8) → C11H16N2O6S2 (1049038-15-4)

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 25℃; Mitsunobu reaction; Cooling with ice;	100%

TrocNHOSO2NH2 (1310054-46-6) + 3-hydroxy-2-methyl-1-propene (513-42-8) → C7H11Cl3N2O5S (1310054-22-8)

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Mitsunobu reaction; Cooling with ice;	100%

1-(methylsufonyl)-4-fluorobenzene (455-15-2) + 3-hydroxy-2-methyl-1-propene (513-42-8) → C11H14O3S

Conditions	Yield
With sodium hydride In tetrahydrofuran at 0 - 20℃; for 20h;	100%

N-(p-toluenesulfonyl)aziridine (3634-89-7) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 2-isopropyl-3-tosyloxazolidine

Conditions	Yield
Stage #1: N-(p-toluenesulfonyl)aziridine; 3-hydroxy-2-methyl-1-propene In dichloromethane at 0℃; for 0.166667h; Stage #2: With Amberlyst-15 In dichloromethane at 0 - 20℃; for 4h;	100%

trichloroacetonitrile (545-06-2) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 2-methyl-2-propenyl trichloroacetimidate (84820-25-7)

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 0℃; for 22h; Inert atmosphere;	99%
(i) Na, (ii) /BRN= 605572/; Multistep reaction;
With sodium hydride In tetrahydrofuran at 0℃; for 2h;
With sodium hydride In diethyl ether at 0℃; Esterification;

benzoyl chloride (98-88-4) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 2-methylallyl benzoate (829-53-8)

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	99%
With triethylamine In tetrahydrofuran at 0 - 20℃; for 26h;	72%
With pyridine In dichloromethane at 0 - 23℃; for 2.25h; Inert atmosphere; Autoclave;	70%

3-Chloro-2-methylpropene (563-47-3) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With sodium hydrogencarbonate; acrylonitrile; hydroquinone In water at 40 - 67℃; for 5.5h; Reagent/catalyst; Temperature;	99.05%
With t-butylnitrite; water; sodium hydrogencarbonate; acrylonitrile at 45 - 67℃; for 3h; Catalytic behavior; Reagent/catalyst;	99.05%
With 5,5-Dimethyl-1-pyrroline N-oxide; phenyl tert-butylmethyldimethoxysilane; water; sodium acetate; sodium carbonate; acetonitrile at 45 - 67℃; for 2.5h; Catalytic behavior; Reagent/catalyst;	99.02%

2-methylpropenal (78-85-3) + cyclohexanol (108-93-0) → cyclohexanone (108-94-1) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With TEMPOL; SnO2#Nb2O5 at 90℃; under 3000.3 Torr; for 10h; Inert atmosphere;	A 95.33% B n/a

methallyl formate (820-57-5) → formamide (77287-34-4, 77287-35-5, 60100-09-6) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With aluminum oxide; ammonia at 0 - 5℃; Gas phase; Large scale;	A 850 g B 95%

2-methylpropenal (78-85-3) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With hydrogen In water at 70℃; under 11251.1 Torr; for 1.5h; Temperature; Reagent/catalyst; Pressure;	94%
With hydrogen In water at 70℃; under 3000.3 Torr; Temperature; Reagent/catalyst; Pressure;	89%
With sodium tetrahydroborate; pyrographite In tetrahydrofuran; water at 20℃; for 0.0166667h;	85%

sodium acetate (127-09-3) + 3-Chloro-2-methylpropene (563-47-3) → methallyl acetate (820-71-3) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With sodium D-gluconate; copper(II) sulfate In water for 4h; Reagent/catalyst; Reflux;	A 92% B 5.5%

2-methyl-1,2-epoxypropane (558-30-5) → isobutyraldehyde (78-84-2) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
lithium phosphate at 210℃; for 3h; Kinetics; Thermodynamic data; 110 - 180 degC , ΔG, ΔH, E(activ.);	A 5.79% B 85.1%
With hydrogen; lithium phosphate at 210℃; for 3h;	A 5.79% B 85.1%
With 3-chlorobenzoate; methanesulfonic acid In dichloromethane-d2 at 26.5℃; Product distribution; various conc. of methanesulfonic acid in the presence and absence of 3-chlorobenzoic acid;	A 10% B 20%
With 3-chlorobenzoate; methanesulfonic acid In dichloromethane-d2 at 26.5℃;	A 10% B 20%

methacrylic acid methyl ester (80-62-6) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether at -30℃; for 4h; Reduction;	83%
With lithium aluminium tetrahydride In diethyl ether at 0℃; for 1h;	72%

(+/-)-2-Methyl-2,3-oxiranemethanol acetate → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With tellurium; lithium triethylborohydride In tetrahydrofuran for 0.166667h; Ambient temperature;	70%

methanol (67-56-1) + propan-1-ol (71-23-8) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With ZnO/MgZrOx mixed oxide with 4.3 Mg/Zr atomic ratio on MgO nanaosheet at 275℃; Inert atmosphere;	17%

2,5-dimethyl-3,4-dihydro-2H-pyran-2-methanol (54004-34-1) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With aluminum oxide at 500℃;

2-methyl-3-bromo-1-propene (1458-98-6) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With potassium carbonate

isopropenylmethyl ether (628-56-8) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With aluminum oxide; copper(II) sulfate at 225℃; under 760 Torr;

methyl methacrylate (97-63-2) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With lithium aluminium tetrahydride; diethyl ether
With diisobutylaluminium hydride In hexane; dichloromethane at -78℃; for 1.5h; Inert atmosphere;

2-methylpropenal (78-85-3) → 2-methyl-propan-1-ol (78-83-1) + isobutyraldehyde (78-84-2) + acetone (67-64-1) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With magnesium oxide; isopropyl alcohol; boron trioxide at 270℃; other α,β-unsaturated corbonyl compounds, other alcohols;

2-methyl-3-prop-2-enyl phenylselenide (59085-70-0) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With dihydrogen peroxide In pyridine; dichloromethane at 0℃; for 0.333333h; Yield given;

methylmagnesium bromide (75-16-1) + propargyl alcohol (107-19-7) → (Z)-(3-<2H>)-2-methylprop-2-en-1-ol (89732-64-9) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With hydrogenchloride; copper(l) iodide; water-d2 1.) THF, -60 deg C up to RT, 2.) THF, Et2O, H2O, pH=7; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

2-methylpropenal (78-85-3) → 2-methyl-propan-1-ol (78-83-1) + isobutyraldehyde (78-84-2) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With hydrogen; AuZr(O) at 89.9℃; Product distribution; pulse reactor; other temperatures;	A 6.7 % Turnov. B 42.9 % Turnov. C 47.2 % Turnov.

2-chloromethyl-2-methyloxiran (598-09-4) → 1-methylcyclopropanol (29526-99-6) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With magnesium In tetrahydrofuran Heating; Title compound not separated from byproducts;

2-(2-methylallyloxy)tetrahydro-2H-pyran (53250-10-5) → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
zeolite HSZ-330 In methanol for 2h; Ambient temperature;

isobutene (115-11-7) + oxygen → 3-methyl-butan-2-one (563-80-4) + acetone (67-64-1) + 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
at 200 - 240℃; under 58840.6 Torr;

isobutenyl chloride → 3-hydroxy-2-methyl-1-propene (513-42-8)

Conditions	Yield
With potassium hydroxide
With water; potassium carbonate man destilliert die erhaltene Loesung und Schuettelt das Destillat mit K2CO3, wobei das Isopropenylcarbinol abgeschieden wird, das man ueber CaO entwaessert;

Upstream product

• 54004-34-1 2,5-dimethyl-3,4-dihydro-2H-pyran-2-methanol 
• 78-85-3 2-methylpropenal 
• 1458-98-6 2-methyl-3-bromo-1-propene 
• 628-56-8 isopropenylmethyl ether 
• 97-63-2 methyl methacrylate 
• 563-47-3 3-Chloro-2-methylpropene 
• 558-30-5 2-methyl-1,2-epoxypropane 
• 59085-70-0 2-methyl-3-prop-2-enyl phenylselenide 
• 75-16-1 methylmagnesium bromide 
• 107-19-7 propargyl alcohol 
• 598-09-4 2-chloromethyl-2-methyloxiran 
• 53250-10-5 2-(2-methylallyloxy)tetrahydro-2H-pyran 
• 115-11-7 isobutene 
• 64-19-7 acetic acid 

Downstream Products

• 873376-29-5 γ-pyrrolidino-isobutyl alcohol 
• 30249-14-0 β-Methyl-piperazin-1-propanol 
• 110358-10-6 γ-(4-methyl-piperazino)-isobutyl alcohol 
• 820-71-3 methallyl acetate 
• 92304-03-5 2-isopropyl-5-methyl-[1,3]dioxolan-4-one 
• 78-84-2 isobutyraldehyde 
• 93430-27-4 butyraldehyde dimethallylacetal 
• 20720-12-1 methallyl propionate 
• 6290-52-4 isobutyraldehyde bis(methallyl) acetal 
• 818-67-7 acrylic acid methallyl ester 
• 816-74-0 methallyl methacrylate 
• 816-73-9 2-methylallyl isobutyrate 
• 628-56-8 isopropenylmethyl ether 
• 64057-79-0 bis(2-methylallyl) carbonate 

Relevant articles and documents

Tailoring Polyethers for Post-polymerization Functionalization by Cross Metathesis

Olefin cross metathesis is reported for the first time to attach small molecules to a range of novel polyethers with a poly(ethylene glycol) backbone and pendent alkene groups, allowing for a loading of up to one compound per monomer unit. These polymers are tailored to prevent the occurrence of self metathesis (reaction of the polymer with itself) by varying the substitution on the pendent alkenes, thus steering their reactivity toward olefin cross metathesis. Efficient functionalization has been observed for a range of coupling partners as a proof of concept for the use of olefin metathesis to graft small and larger molecules to polyethers for drug delivery. This approach also paves the way for the use of olefin cross metathesis as an efficient method to functionalize a wide variety of polymers with pendent olefin groups.

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METHOD FOR PREPARING 2-METHALLYL ALCOHOL

2 - Allyl chloride is reacted in the presence of a catalyst in a basic aqueous solution. The catalyst is an ionic liquid (Ionic liquid) and relates to a method for producing 2 -methallyl alcohol. To the present invention, 2 - metaallyl alcohol having high selectivity and high yield can be provided.

METHOD FOR SEPARATING AND PREPARING 2-METHALLYL ALCOHOL

The reaction of 2 -methallyl chloride with a basic aqueous solution to produce a 1-phase reaction solution (Step 1). 1: The reaction solution 2 is prepared by adding an aqueous alkali metal salt solution or an alkaline earth metal salt aqueous solution to the reaction solution to produce an agent 2. The method 2 according to claim 3, wherein the reaction mixture is separated into a water layer and an oil layer. The 2 -methallyl alcohol according to claim 4, wherein 2 -allyl alcohol is separated from the oil layer. To the present invention, 2 - metaallyl alcohol can be separated and recovered at a high recovery rate.