51307-01-8

Basic information

• Product Name: 2-Cyclopenten-1-one, 2-hydroxy-3-phenyl-
• CAS NO: 51307-01-8
• Molecular Formula: C11H10O2
• Molecular Weight: 174.199
• Mol File: 51307-01-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Cyclopenten-1-one, 2-hydroxy-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-one, 2-hydroxy-3-phenyl-(51307-01-8)
• EPA Substance Registry System: 2-Cyclopenten-1-one, 2-hydroxy-3-phenyl-(51307-01-8)

Safety Data

• Hazardous Substances Data: 51307-01-8(Hazardous Substances Data)

Upstream product

• 70107-41-4 5-hydroxy-1-phenylpentane-1,4-dione 
• 939-56-0 benzoyloxyacetonitrile 
• 3019-83-8 3-bromo-2-hydroxycyclopent-2-en-1-one 
• 98-80-6 phenylboronic acid 
• 6362-68-1 3-phenyl-cyclopentane-1,2,4-trione 
• 51307-00-7 2-Phenyl-3,5,5-triethoxy-2-cyclopenten-1-on 
• 94034-53-4 5'-cinnamylidenecyclohexanespiro-2'-(1',3'-dioxolan)-4'-one 
• 76713-84-3 acetic acid 2,5-dioxo-5-phenylpentyl ester 

Downstream Products

• 2051-95-8 succinylbenzene 

Relevant articles and documents

Convenient and easy access to 2-hydroxycyclopent-2-enones from acylcyanohydrins

A convenient access to 2-hydroxycyclopentenones was designed from acylcyanohydrins, by using titanacyclopropane complexes as nucleophilic partners and an intramolecular aldol condensation in basic conditions. The development of a one-pot procedure allows a step- and atom-economic process, and the use of Grignard reagents other than ethylmagnesium bromide provided valuable 3,4-disubstituted 2-hydroxycyclopentenones. The utility of the hydroxy group was illustrated by further functionalization of the α-position using palladium-mediated cross-coupling reactions.

Asymmetric synthesis of 2-aryl-5-oxotetrahydrofuran-2-carboxylic acids

3-Aryl-2-hydroxycyclopent-2-en-1-ones, when subjected to asymmetric oxidation, result in enantiomerically enriched 2-aryl-5-oxotetrahydrofuran-2- carboxylic acids. Electron-donating substituents in the para position of the phenyl ring increase the yield and decrease the enantioselectivity of the process. Georg Thieme Verlag Stuttgart.

ADDITION VON ALDEHYDEN AN AKTIVIERTE DOPPELBINDUNGEN, XXVII. MITTEILUNG : EIN EINFACHER WEG ZU 2-HYROXY-CYCLOPENTENONEN

A new, easy synthetic route to 2-hydroxy-3-alkyl-cyclopentenones starting from the thiazolium salt catalyzed addition of aldehydes to 1-acetoxy-3-buten-2-one is described.