51410-44-7

Basic information

• Product Name: 1'-hydroxyestragole
• Synonyms: 1'-hydroxyestragole;p-Methoxy-α-vinylbenzyl alcohol;α-Vinyl-4-methoxybenzenemethanol
• CAS NO: 51410-44-7
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.203
• Mol File: 51410-44-7.mol
• Article Data: 95

Chemical Properties

• Boiling Point: 231.67°C (rough estimate)
• Flash Point: 119.6°C
• Appearance: /
• Density: 1.0041 (rough estimate)
• Vapor Pressure: 0.0022mmHg at 25°C
• Refractive Index: 1.5190 (estimate)
• CAS DataBase Reference: 1'-hydroxyestragole(CAS DataBase Reference)
• NIST Chemistry Reference: 1'-hydroxyestragole(51410-44-7)
• EPA Substance Registry System: 1'-hydroxyestragole(51410-44-7)

Safety Data

• Hazardous Substances Data: 51410-44-7(Hazardous Substances Data)

Usage

Properties

Different sources of media describe the Properties of 51410-44-7 differently. You can refer to the following data:
1. Naturally occurring compound
2. Phenolic compound
3. Potential carcinogen
4. Regulatory restrictions
5. Therapeutic benefits

Specific content

Different sources of media describe the Specific content of 51410-44-7 differently. You can refer to the following data:
1. Found in various essential oils, particularly in tarragon and basil
2. Possesses significant antioxidant and antifungal properties
3. Classified as a genotoxic carcinogen by the European Food Safety Authority
4. Imposed on the use of estragole in food and beverages by regulatory agencies
5. Research into potential benefits in cancer treatment and prevention is ongoing

InChI:InChI=1/C10H12O2/c1-3-10(11)8-4-6-9(12-2)7-5-8/h3-7,10-11H,1H2,2H3

Upstream product

• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 107-02-8 acrolein 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 
• 317835-38-4 C₁₆H₁₅NO₃Se 
• 53484-50-7 (E)-p-methoxy-cinnamyl alcohol 
• 593-60-2 Vinyl bromide 
• 4698-23-1 N-methyl-3,4,5-trimethoxyphenylpropiolamide 
• 123-11-5 4-methoxy-benzaldehyde 
• 4392-24-9 Cinnamyl bromide 
• 1826-67-1 vinyl magnesium bromide 
• 104-88-1 4-chlorobenzaldehyde 
• 53484-50-7 p-methoxycinnamyl alcohol 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 94607-41-7 para-methoxycinnamyl chloride 
• 138958-75-5 5-<3-(4-methoxyphenyl)-2-propenyl>-1,3-benzodioxol-6-ol 
• 97998-80-6 4-Methoxy-7-methyl-bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-triene-7-carboxylic acid 1-(4-methoxy-phenyl)-allyl ester 
• 136120-33-7 2-<3-<4-Methoxyphenyl>prop-2-enyl>-2-trifluoromethylcyclopentane-1,3-dione 
• 106093-48-5 1--1-(p-methoxyphenyl)-2propene 
• 7448-86-4 1-(4-methoxyphenyl)prop-2-en-1-one 
• 140439-86-7 anti-3-(4-methoxyphenyl)pent-4-en-2-ol 
• 140439-86-7 syn-3-(4-methoxyphenyl)pent-4-en-2-ol 
• 53484-50-7 p-methoxycinnamyl alcohol 
• 66821-64-5 2-(4-Methoxycinnamyl)-5-methoxyhydrochinon 
• 250712-58-4 Ethyl 3-[1-(4-methoxyphenyl)allyloxy]propionate 
• 61691-82-5 1'-acetoxyestragole 
• 309723-10-2 1-(1-allyloxyallyl)-4-methoxybenzene 
• 587885-30-1 (R)-(+)-1-(p-methoxyphenyl)-2-propen-1-ol 

Relevant articles and documents

Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol

One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.

Iridium-Catalyzed Asymmetric Allylic Alkylation of Deconjugated Butyrolactams

Compared with the ever-growing list of nonprochiral nucleophiles in Ir-catalyzed asymmetric allylic substitution reactions, prochiral nucleophiles are less studied. We present a new prochiral nucleophile, namely, deconjugated butyrolactam, for Ir-catalyze

Enantioselective Allylation of Alkenyl Boronates Promotes a 1,2-Metalate Rearrangement with 1,3-Diastereocontrol

Alkenyl boronates add to Ir(π-allyl) intermediates with high enantioselectivity. A 1,2-metalate shift forms a second C-C bond and sets a 1,3-stereochemical relationship. The three-component coupling provides tertiary boronic esters that can undergo multiple additional functionalizations. An extension to trisubstituted olefins sets three contiguous stereocenters.