51560-17-9

Basic information

• Product Name: Benzene, 1,5-diiodo-2,4-dimethoxy-
• Synonyms: Benzene,1,5-diiodo-2,4-dimethoxy
• CAS NO: 51560-17-9
• Molecular Formula: C8H8I2O2
• Molecular Weight: 389.959
• Mol File: 51560-17-9.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Benzene, 1,5-diiodo-2,4-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,5-diiodo-2,4-dimethoxy-(51560-17-9)
• EPA Substance Registry System: Benzene, 1,5-diiodo-2,4-dimethoxy-(51560-17-9)

Safety Data

• Hazardous Substances Data: 51560-17-9(Hazardous Substances Data)

Upstream product

• 20469-63-0 1-iodo-2,4-dimethoxybenzene 
• 109-63-7 trifluoroborane diethyl ether 
• 7647-01-0 hydrogenchloride 
• 60-29-7 diethyl ether 
• 91-16-7 1,2-dimethoxybenzene 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 150-78-7 1,4-dimethoxybezene 
• 19514-91-1 4,6-diiodobenzene-1,3-diol 
• 74-88-4 methyl iodide 
• 151-10-0 1,3-Dimethoxybenzene 
• 71-43-2 benzene 
• 7550-45-0 titanium tetrachloride 
• 7446-70-0 aluminium trichloride 
• 64-17-5 ethanol 

Downstream Products

• 20469-63-0 1-iodo-2,4-dimethoxybenzene 
• 1329995-89-2 1,3-dimethoxy-4,6-bis[(Z)-3,3,3-trifluoropropenyl]benzene 
• 1329995-88-1 1,3-dimethoxy-4,6-bis[(E)-3,3,3-trifluoropropenyl]benzene 
• 1329995-91-6 1,5-dimethoxy-2,4-bis(3,3,3-trifluoropropynyl)benzene 

Relevant articles and documents

Photocatalytic Oxidative Iodination of Electron-Rich Arenes

A visible-light-mediated oxidative iodination of electron-rich arenes has been developed. 2.5 mol% of unsubstituted anthraquinone as photocatalyst were used in combination with elementary iodine, trifluoroacetic acid and oxygen as the terminal oxidant. The iodination proceeds upon irradiation in non- or weakly-electron donating solvents (DCM, DCE and benzene) wherein a spectral window in strongly coloured iodine solutions can be observed at around 400 nm. The method provides good to excellent yields (up to 98%) and shows excellent regioselectivity and good functional group tolerance (triple bonds, ketone, ester, amide). Moreover, the photo-iodination was also upscaled to a 5 mmol scale (1.1 g). Mechanistic investigations by intermediate trapping and competition experiments indicate a photocatalytic arene oxidation and the subsequent reaction with iodine as a likely mechanistic pathway. (Figure presented.).

Method for synthesizing mono-aryl iodide or di-aryl iodide based on aromatic hydrocarbon carboxylic acid decarboxylic reaction

The invention discloses a method for synthesizing mono-aryl iodide or di-aryl iodide based on aromatic hydrocarbon carboxylic acid decarboxylic reaction. The method is characterized in that under a protective atmosphere, carrying out one-pot reaction on a

Bronsted acidic ionic liquid accelerated halogenation of organic compounds with N-halosuccinimides (NXS)

The Bronsted-Acidic ionic liquid 1-methyl-3-(4-sulfobutyl) imidazolium triflate [BMIM(SO3H)][OTf] was demonstrated to act efficiently as solvent and catalyst for the halogenation of activated organic compounds with N-halosuccinimides (NXS) under mild conditions with short reaction times. Methyl aryl ketones were converted into a-halo and a,a-dihaloketones, depending on the quantity of NXS used. Ketones with activated aromatic rings were selectively halogenated, however in some cases mixtures of a-halogenated ketone and ring-halogenated ketones were obtained. Activated aromatics were regioselectively ring halogenated to give mono- and dihalo-substituted products. The [BMIM(SO3H)][OTf] ionic liquid (IL-A) was successfully reused eight times in a representative monohalogenation reaction with no noticeable decrease in efficiency. An effective halogenation scale-up in this IL is also presented. The reactivity trend and the observed chemo- and regioselectiivities point to an ET process in these IL-promoted halofunctionalization reactions.