520-32-1Relevant articles and documents
A sulphated flavone glycoside from Livistona australis and its antioxidant and cytotoxic activity
Kassem, Mona E.S.,Shoela, Soha,Marzouk, Mona M.,Sleem, Amany A.
, p. 1381 - 1387 (2012)
A new flavone glycoside tricin 7-O - glucopyranoside-2-sulphate sodium salt along with 14 known flavonoid compounds were isolated and identified from the aqueous methanol extract of Livistona australis leaves. Their structures were established on the basis of extensive NMR (1H, 13C, HSQC and H-H COSY) and ESIMS data. Antioxidant and cytotoxicity properties of the methanol extract of the leaves as well as the new compound were investigated.
Flavonoid pattern inheritance in the allopolyploid Spartina anglica – Comparison with the parental species S. maritima and S. alterniflora
Grignon-Dubois, Micheline,De Montaudouin, Xavier,Rezzonico, Bernadette
, (2020/03/27)
The invasive species Spartina anglica arose in Europe by a cross between the Afro-European species S. maritima (native, paternal ancestor) and the introduced North American S. alterniflora (invasive, maternal ancestor). Aqueous methanolic extracts were prepared from plant tissue for chemotaxonomical comparison between the three species and determination of the phenolic pattern inheritance in S. anglica. A total of 20 phenolic compounds were detected in the aerial tissues of S. anglica and S. alterniflora, but only seven in S. maritima. They were isolated from their respective crude extracts, and their structures were determined according to spectroscopic data analysis and chemical evidence. They all belong to the flavonoid class, with 13 of them identified as C-glycoflavonoid and seven as O-glycoflavonoid. All these products were detected for the first time from S. anglica, fourteen of them for the first time from S. alterniflora, and three of them for the first time from S. maritima. The individual concentrations in the three species were determined by quantitative HPLC. The two parental species were found to differ markedly in their foliar phenolic fingerprint, whereas that of S. anglica showed a clear maternal dominance. Eight of the fourteen major compounds identified were of maternal origin among which, six were over-expressed, only three were from paternal origin but under-regulated, while two originated from the two parents. As far as we know, this work represents the first exhaustive report of the phenolic fingerprints of S. alterniflora and S. anglica and of the phenolic pattern inheritance in S. anglica. The similarity in the phenolic chemistry of the introduced and invasive S. alterniflora to its progeny could play a role in the physiological vigour and invasion success of S. anglica. This work provide a foundation for further studies, considering the reported biological activities of C-glycosidic flavonoids and tricin derivatives, and the lack of knowledge of the ecological chemistry of the genus Spartina.
Synthesis method of 5,7,4'-trihydroxy-3',5'-dimethoxyflavone
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Paragraph 0012; 0020-0036, (2019/10/01)
The invention discloses a synthesis method of 5,7,4'-trihydroxy-3',5'-dimethoxyflavone (I), and belongs to the technical field of preparation methods of chemical medicinal intermediates. The synthesismethod comprises the following steps: with 1,3,5-trihydroxybenzene (II) and ethyl cyanoacetate as raw materials, performing a condensation reaction to obtain 2-(2-chloro-1-iminoethyl)benzene-1, 3, 5-triphenol (III), then hydrolyzing the (III) in dilute hydrochloric acid to obtain 2-chloro-1-(2,4,6-trihydroxyphenyl)ethanone (IV), and then cyclizing the IV with 3,5-dimethoxy-4-hydroxybenzaldehyde in the presence of alkali to obtain the 5,7,4'-trihydroxy-3',5'-dimethoxyflavone (I). The used raw materials are relatively cheap and easy to obtain, the method is easy and convenient to operate, the product yield is relatively high, and a relatively high industrialization value is achieved.
