52395-99-0 Usage
Uses
Used in Pharmaceutical Industry:
Belarizine is used as an antipsychotic medication for the treatment of schizophrenia and other psychotic disorders.
It is used to block the effects of dopamine in the brain, helping to reduce psychotic symptoms such as hallucinations and delusions.
Used in Research and Development:
Belarizine is being studied for its potential use in the treatment of bipolar disorder and depressive disorders, expanding its application in the field of mental health.
Check Digit Verification of cas no
The CAS Registry Mumber 52395-99-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,9 and 5 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 52395-99:
(7*5)+(6*2)+(5*3)+(4*9)+(3*5)+(2*9)+(1*9)=140
140 % 10 = 0
So 52395-99-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H26N2O/c27-23-13-11-20(12-14-23)19-25-15-17-26(18-16-25)24(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14,24,27H,15-19H2
52395-99-0Relevant articles and documents
New serine protease inhibitors with leukotriene B4 (LTB4) receptor binding affinity
Nakayama, Yoshisuke,Senokuchi, Kazuhiko,Sakaki, Katsuhito,Kato, Masashi,Maruyama, Toru,Miyazaki, Toru,Ito, Hidenori,Nakai, Hisao,Kawamura, Masanori
, p. 971 - 985 (2007/10/03)
A series of new trypsin-like serine protease inhibitors, 1, 2 and 7-23, containing amidinobenzene moiety was found to show potent LTB4-receptor affinity. Among them, compounds 1 and 2 were found to be LTB4 receptor antagonists based on an inhibition assay of human polymorphonuclear neutrophil (PMN) intracellular calcium mobilization induced by LTB4. Compounds 1 and 2, which satisfy the reported structural requirements for good oral activity, are expected to show a balanced dual mode of action, i.e., protease inhibitory activity and LTB4 receptor antagonist activity, in vivo.
