53360-90-0

Basic information

• Product Name: Hexahydro-2-(nitroimino)-pyrimidine
• Synonyms: Hexahydro-2-(nitroimino)-pyrimidine
• CAS NO: 53360-90-0
• Molecular Formula: C₄H₈N₄O₂
• Molecular Weight: 144.1319
• Mol File: 53360-90-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 267.5 °C at 760 mmHg
• Flash Point: 115.6 °C
• Appearance: /
• Density: 1.64 g/cm³
• CAS DataBase Reference: Hexahydro-2-(nitroimino)-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: Hexahydro-2-(nitroimino)-pyrimidine(53360-90-0)
• EPA Substance Registry System: Hexahydro-2-(nitroimino)-pyrimidine(53360-90-0)

Safety Data

• Hazardous Substances Data: 53360-90-0(Hazardous Substances Data)

Usage

General Description

Hexahydro-2-(nitroimino)-pyrimidine is a chemical compound with the molecular formula C4H10N4O2. It is a highly reactive and potentially unstable compound, consisting of a six-membered ring containing nitrogen, oxygen, and carbon atoms. It is commonly used in the synthesis of various pharmaceuticals, agrochemicals, and organic compounds. Hexahydro-2-(nitroimino)-pyrimidine is known for its role as a precursor in the production of insecticides and is also used in the formulation of certain pharmaceutical drugs. However, it is important to handle this compound with care due to its potential instability and reactivity.

InChI:InChI=1/C4H9N4O2/c9-8(10)7-4-5-2-1-3-6-4/h1-3H2,(H,9,10)(H2,5,6,7)/q+1

Upstream product

• 109-76-2 Trimethylenediamine 
• 556-88-7 nitroguanidine 
• 2986-25-6 methyl nitrocarbamimidothioate 
• 506-93-4 guanidine nitrate 
• 556-88-7 2-nitroguanidine 
• 141972-53-4 S,S-dimethyl N-(nitro)imidodithiocarbonate 

Downstream Products

• 7697-37-2 nitric acid 
• 53360-92-2 1-phenyl-3-(1,4,5,6-tetrahydro-pyrimidin-2-ylamino)-propan-1-ol 

Relevant articles and documents

Quinoline and 2-nitroimino-1, 3-diazacycloalkane hybrids: Design, synthesis and insecticidal activity

A library of new hybrid molecules comprising quinoline, 2-nitroimino-1, 3-diazacycloalkane motifs were designed and synthesized as plausible neonicotinoid analogues. These compounds were synthesized from 2-chloro/aryloxy-3-formyl quinolines and guanidine nitrate with the coupling of 2-chloro/aryloxy-3-(chloromethyl)quinolines, 2-nitroimino-1, 3-diazacycloalkanes under phase transfer catalysis (PTC) as crucial step. All the compounds were obtained in excellent yields (80–90%) and were characterized by 1H, 13C NMR and mass spectrometry. The newly generated compounds were screened for insecticidal activity against aphids in safflower field and some of them displayed moderate activity.

Synthesis of 2-nitroimino-1,3-diazacycloalkanes

An efficient, practical and enviro-friendly method of preparation of 2-nitroimino-1,3-diazacycloalkanes 3a-d has been reported by a simple reaction between nitroguanidine 1 and diamines 2a-d in the presence of conc. HCl in aq. medium with very good yields.

PROCESS FOR PRODUCING NITROGENOUS HETEROCYCLE

A process for producing a nitrogenous heterocycle represented by general formula (III) by the reaction of an N-nitroimidodithiocarbonate represented by general formula (I) with a diamine represented by general formula (II), wherein R1 and R2 represent each alkyl; R3 and R4 represent each hydrogen or alkyl which may be substituted with a heterocycle; R5 represents hydrogen or alkyl; and n represents 2 to 4.