535921-10-9

Basic information

• Product Name: 4-oxo-3-phenyl-1,4-dihydro-5-oxa-1-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester
• CAS NO: 535921-10-9
• Molecular Weight: 319.317
• Mol File: 535921-10-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-oxo-3-phenyl-1,4-dihydro-5-oxa-1-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-3-phenyl-1,4-dihydro-5-oxa-1-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester(535921-10-9)
• EPA Substance Registry System: 4-oxo-3-phenyl-1,4-dihydro-5-oxa-1-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester(535921-10-9)

Safety Data

• Hazardous Substances Data: 535921-10-9(Hazardous Substances Data)

Upstream product

• 535921-05-2 (3-benzoyl-2-oxo-2H-chromen-4-ylamino)-acetic acid methyl ester 
• 19492-11-6 3-benzoyl-4-hydroxy-2H-chromen-2-one 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 16709-58-3 2-oxo-2H-chromen-4-yl benzoate 
• 535921-01-8 4-methoxy-3-benzoylcoumarin 

Relevant articles and documents

Efficient synthesis of trisubstituted [1]benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives from 4-hydroxycoumarin

Various trisubstituted [1]benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives have been synthesized from 4-hydroxycoumarin with a 30-40% yield over six steps. The key step of the synthesis is a base-promoted intramolecular cyclization of enamines 5, followed by dehydration to generate the fused pyrrole ring.