537697-28-2 Usage
Uses
Used in Pharmaceutical Synthesis:
O-Methyl-D-threonine is utilized as a building block in the synthesis of various natural products and pharmaceuticals, contributing to the development of new therapeutic agents.
Used in Cancer Therapeutics Development:
In the field of oncology, O-Methyl-D-threonine is used as a key component in the development of therapeutics targeting cancer. Its potential lies in its ability to be incorporated into compounds that can combat neoplastic diseases.
Used in Antibacterial Agents Production:
O-Methyl-D-threonine plays a crucial role in the production of antibiotics, serving as a fundamental constituent in the creation of substances that fight bacterial infections.
Used in Neurological Disorders Treatment:
O-Methyl-D-threonine is also applied in the development of treatments for neurological disorders, showcasing its potential to address a range of conditions affecting the nervous system.
Used in Antitumor Agents Production:
O-Methyl-D-threonine is a vital component in the synthesis of antitumor agents, highlighting its importance in cancer treatment and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 537697-28-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,7,6,9 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 537697-28:
(8*5)+(7*3)+(6*7)+(5*6)+(4*9)+(3*7)+(2*2)+(1*8)=202
202 % 10 = 2
So 537697-28-2 is a valid CAS Registry Number.
537697-28-2Relevant articles and documents
Minutissamides E-L, antiproliferative cyclic lipodecapeptides from the cultured freshwater cyanobacterium cf. Anabaena sp.
Kang, Hahk-Soo,Sturdy, Megan,Krunic, Aleksej,Kim, Hyunjung,Shen, Qi,Swanson, Steven M.,Orjala, Jimmy
, p. 6134 - 6143 (2012/11/07)
The extract of UIC 10035, a strain obtained from a sample collected near the town of Homestead, South Florida, showed antiproliferative activity against MDA-MB-435 cells. Bioassay-guided fractionation led to the isolation of a series of cyclic lipodecapeptides, named minutissamides E-L (1-8). The planar structures were determined by analysis of HRESIMS, tandem MS, and 1D and 2D NMR data, and the stereoconfigurations were assigned by LC-MS analysis of the Marfey's derivatives after acid hydrolysis. Minutissamides E-L (1-8) exhibited antiproliferative activity against MDA-MB-435 cells with IC50 values ranging between 1 and 10 μM. The structures of minutissamides E-L (1-8) were closely related with those of the previously reported lipopeptides, puwainaphycins A-E and minutissamides A-D, characterized by the presence of a lipophilic β-amino acid and three non-standard amino acids NMeAsn, OMeThr and Dhb (α,β-dehydro-α-aminobutyric acid). The strain UIC 10035 was designated as cf. Anabaena sp. on the basis of morphological and 16S rRNA gene sequence analyses.
