5379-88-4Relevant articles and documents
Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists
Yin, Xiu-Juan,Huang, Xiao-Yan,Ma, Yun-Bao,Geng, Chang-An,Li, Tian-Ze,Chen, Xing-Long,Yang, Tong-Hua,Zhou, Jun,Zhang, Xue-Mei,Chen, Ji-Jun
, p. 610 - 622 (2017/05/26)
Twenty-four gramine derivatives were synthesized and evaluated on MT1 and 5-HT1A receptors in vitro. Among them, seven derivatives (7, 8, 16, 19, 20, 21, and 24) exhibited higher agonisting activities on MT1 or 5-HT1A
12-Tungstophosphoric acid immobilized on γ-Fe2O 3@SiO2 coreshell nanoparticles: An effective solid acid catalyst for the synthesis of indole derivatives in water
Rafiee, Ezzat,Eavani, Sara,Malaekeh-Nikouei, Bizhan
scheme or table, p. 438 - 440 (2012/06/01)
12-Tungstophosphoric acid immobilized on γ-Fe2O 3@SiO2 coreshell nanoparticles was used as novel solid acid catalyst for the synthesis of various bis(indolyl)methanes and β-functionalized indoles in water. The catalyst can
Ruthenium-catalyzed /V-alkylation of amines and sulfonamides using borrowing hydrogen methodology
Hamid, M. Haniti S. A.,Allen, C. Liana,Lamb, Gareth W.,Maxwell, Aoife C.,Maytum, Hannah C.,et al.
supporting information; experimental part, p. 1766 - 1774 (2009/07/25)
The alkylation of amines by alcohols has been achieved using 0.5 mol percent [Ru(p-cymene)CI2]2 with the bidentate phosphines dppf or DPEphos as the catalyst. Primary amines have been converted into secondary amines, and secondary amines into tertiary amines, including the syntheses of Piribedil, Tripelennamine, and Chlorpheniramine. A/-Heterocyclization reactions of primary amines are reported, as well as alkylation reactions of primary sulfonamides. Secondary alcohols requiremore forcing conditions than primary alcohols but are still effective a lkylating agents in the presence of this catalyst.