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53942-45-3

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  • O-3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-O-3,6-di-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-1,3,6-triacetate-a-D-glucopyranose

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  • O-3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-O-3,6-di-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-1,3,6-triacetate-a-D-glucopyranose

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  • O-3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-O-3,6-di-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-1,3,6-triacetate-a-D-glucopyranose

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  • O-3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-O-3,6-di-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-1,3,6-triacetate-a-D-glucopyranose

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53942-45-3 Usage

Uses

Different sources of media describe the Uses of 53942-45-3 differently. You can refer to the following data:
1. An intermediate of 4-Methylumbelliferyl -D-N,N?N?Triacetylchitotrioside
2. An intermediate of 4-Methylumbelliferyl β-D-N,N',N”-Triacetylchitotrioside.
3. An intermediate of 4-Methylumbelliferyl β-D-N,N'',N”-Triacetylchitotrioside.

Check Digit Verification of cas no

The CAS Registry Mumber 53942-45-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,9,4 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 53942-45:
(7*5)+(6*3)+(5*9)+(4*4)+(3*2)+(2*4)+(1*5)=133
133 % 10 = 3
So 53942-45-3 is a valid CAS Registry Number.
InChI:InChI=1/C40H57N3O24/c1-15(44)41-29-36(60-23(9)52)33(27(13-56-19(5)48)63-38(29)62-25(11)54)66-40-31(43-17(3)46)37(61-24(10)53)34(28(65-40)14-57-20(6)49)67-39-30(42-16(2)45)35(59-22(8)51)32(58-21(7)50)26(64-39)12-55-18(4)47/h26-40H,12-14H2,1-11H3,(H,41,44)(H,42,45)(H,43,46)/t26?,27?,28?,29-,30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,40-/m0/s1

53942-45-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Chitotriose undecaacetate

1.2 Other means of identification

Product number -
Other names cyclohexanehexol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53942-45-3 SDS

53942-45-3Relevant articles and documents

Acetylated chitosan oligosaccharides act as antagonists against glutamate-induced PC12 cell death via Bcl-2/Bax signal pathway

Hao, Cui,Gao, Lixia,Zhang, Yiran,Wang, Wei,Yu, Guangli,Guan, Huashi,Zhang, Lijuan,Li, Chunxia

, p. 1267 - 1289 (2015/04/14)

Chitosan oligosaccharides (COSs), depolymerized products of chitosan composed of β-(1→4) D-glucosamine units, have broad range of biological activities such as antitumour, antifungal, and antioxidant activities. In this study, peracetylated chitosan oligosaccharides (PACOs) and N-acetylated chitosan oligosaccharides (NACOs) were prepared from the COSs by chemcal modification. The structures of these monomers were identified using NMR and ESI-MS spectra. Their antagonist effects against glutamate-induced PC12 cell death were investigated. The results showed that pretreatment of PC12 cells with the PACOs markedly inhibited glutamate-induced cell death in a concentration-dependent manner. The PACOs were better glutamate antagonists compared to the COSs and the NACOs, suggesting the peracetylation is essential for the neuroprotective effects of chitosan oligosaccharides. In addition, the PACOs pretreatment significantly reduced lactate dehydrogenase release and reactive oxygen species production. It also attenuated the loss of mitochondrial membrane potential. Further studies indicated that the PACOs inhibited glutamate-induced cell death by preventing apoptosis through depressing the elevation of Bax/Bcl-2 ratio and caspase-3 activation. These results suggest that PACOs might be promising antagonists against glutamate-induced neural cell death.

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