54245-41-9Relevant articles and documents
Production method for 4-bromo fluorenone
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Paragraph 0006; 0016, (2016/10/31)
The invention discloses a production method for 4-bromo fluorenone, belonging to the field of organic chemical synthesis. The production method is realized by comprising the following steps: reacting cyanobenzene as a raw material with o-dibromobenzene under the protection of argon gas and the actions of a palladium catalyst, a copper catalyst and an organic phosphine ligand so as to obtain 2-bromo-2'-carbonitrile biphenyl, and carrying out hydrolyzation and closed-loop synthesizing so as to obtain the 4-bromo fluorenone. The production method for the 4-bromo fluorenone is simple to operate in reaction process, has low production cost and is suitable for industrial production. The 4-bromo fluorenone can be applied in the fields of organic optoelectronic materials, medicines, pesticides, etc.
Synthesis of polysubstituted phenanthridines via ligand-free copper-catalyzed annulation
Chen, Yan-Fu,Hsieh, Jen-Chieh
supporting information, p. 4642 - 4645 (2015/01/08)
A novel procedure for the cascade reaction of the addition of a Grignard reagent to a nitrile with a copper-catalyzed C-N bond coupling was developed, which afforded various polysubstituted phenanthridines in moderate to good yields with tolerance for a wide variety of substrates. Experimental data demonstrated that the reaction proceeded more likely through a Cu(I/III) catalytic cycle.
