544-70-7

Basic information

• Product Name: (9Z,11Z)-octadeca-9,11-dienoic acid
• Synonyms: 9,11-octadecadienoic acid, (9Z,11Z)-
• CAS NO: 544-70-7
• Molecular Formula: C₁₈H₃₂O₂
• Molecular Weight: 280.4455
• Mol File: 544-70-7.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 381.6°C at 760 mmHg
• Flash Point: 278.5°C
• Density: 0.911g/cm³
• Vapor Pressure: 7.01E-07mmHg at 25°C
• Refractive Index: 1.478
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: (9Z,11Z)-octadeca-9,11-dienoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (9Z,11Z)-octadeca-9,11-dienoic acid(544-70-7)
• EPA Substance Registry System: (9Z,11Z)-octadeca-9,11-dienoic acid(544-70-7)

Safety Data

• Hazardous Substances Data: 544-70-7(Hazardous Substances Data)

Usage

Description

9(Z),11(Z)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in milk from cows and other animals. It is cytotoxic to Caco-2 human colon cancer cells (EC50 = 446.1 μM) and induces changes in the miRNA profile, including an upregulation hsa-miR-146a-5p and downregulation of hsa-miR-32-5p, which is involved in apoptosis. [Matreya, LLC. Catalog No. 1248]

Uses

(9Z,11Z)-9,11-Octadecadienoic Acid, is a conjugated Linoleic Acid, a compound that has reported to exhibit anticarcinogenic activity. Linoleic Acid is an anti-inflammatory, acne reductive, and moisture retentive when applied topically on the skin. It is popular in the beauty products industry because of its beneficial properties on the skin.

Upstream product

• 33128-27-7 octadeca-9,11-diynoic acid 
• 2462-85-3 linoleic acid methyl ester 
• 60-33-3 linoleic acid 
• 8001-23-8 safflower oil 
• 2578-97-4 trans-ximenynic acid 
• 56-23-5 tetrachloromethane 
• 111-46-6 diethylene glycol 
• 112-53-8 1-dodecyl alcohol 
• 822-10-6 (9Z,11E)-methyl octadeca-9,11-dienoate 
• 141-22-0 Ricinoleic acid 
• 540-12-5 ricinelaidic acid 
• 81212-19-3 (Z)-12-hydroxyoctadec-9-enoic acid 
• 18829-56-6 (E)-2-Nonenal 
• 88462-46-8 (8-carboxyoctyl)triphenylphosphonium bromide 

Downstream Products

• 822-10-6 octadeca-9,11-dienoic acid methyl ester 
• 544-70-7 trans-9,trans-11-octadecadienoic acid 
• 87-93-4 9r_F,10t_F,11r'_F,12t'_F-tetrahydroxy-octadecanoic acid 
• 95699-23-3 3-<7-Carboxy-heptyl>-6--4,4,5,5-tetracyan-cyclohexen-(1) 
• 822-10-6 (9Z,11E)-methyl octadeca-9,11-dienoate 
• 119589-84-3 9,10;11,12-diepoxy-octadecanoic acid 
• 123-99-9 azelaic acid 
• 111-14-8 oenanthic acid 
• 15719-64-9 methylammonium carbonate 
• 903581-73-7 octadeca-9t,11t-dienoyl chloride 
• 872-23-1 (9E,11Z)-Octadeca-9,11-dienoic acid 
• 1002-79-5 (10E,12Z)-10,12-octadecadienoic acid methyl ester 
• 103281-90-9 8-(4-hexyl-9,10-dioxo-9,10-dihydro-[1]anthryl)-octanoic acid 
• 6114-22-3 9t,11t-octadecadienoic acid ethyl ester 

Relevant articles and documents

Revealing ruthenium and basicity synergetic effects in Ru-MgAl catalysts for isomerization of linoleic acid to conjugated linoleic acid

Ru-MgAl catalysts were prepared by co-precipitation at different pH values (x = 7-12), with the aims of investigating the effect of pH on their catalytic performance for isomerization of linoleic acid to conjugated linoleic acid and of understanding the relationship of basicity site and ruthenium activity site. The results showed that strong basicity and highly dispersed ruthenium may be the active sites for linoleic acid isomerization. Only if all three conditions, i.e., high Ru dispersion, appropriate SMSI effect and high number of strong basicity sites, are fulfilled can highly effective active sites be formed for the isomerization of linoleic acid to conjugated linoleic acid. A possible reaction mechanism for the isomerization was also proposed.

Synergetic effect of ruthenium and basicity sites in the Ru-MgAl catalyst for hydrogen-free production of conjugated linoleic acids

A series of Ru-MgAl composite oxide catalysts prepared by calcining the ruthenium grafted hydrotalcite-like precursor at various temperatures were used in the hydrogen-free production of conjugated linoleic acid. The effect of calcination temperature on the textural, base and catalytic properties of the materials was investigated. Results indicated that the Ru-MgAl composite oxides calcined at 450 °C showed high activity, namely, CLA productivity, CLA production rate and TOF up to 1.52 g CLA g (CLA) L-1 (solvent) min-1, 284 g (CLA) g-1 (Ru) h-1 and 102.6 mol (LA converted) mol-1 (Ru) h-1. Moreover, the biologically active CLA isomers, cis-9, trans-11, trans-10, cis-12 and trans-9, trans-11-CLA, were the main products, while almost no hydrogenated products were formed. Meanwhile, the role of ruthenium and basicity sites in the catalytic reaction has been studied. It was found that the basicity sites of the Ru-MgAl catalyst and the ruthenium activity sites seem to have a synergic effect on the catalytic reaction. The possible reaction mechanism for the isomerization was also proposed. This journal is

Method For The Production Of Conjugated Polyunsaturated Fatty Acids With Heterogenous Catalysts

The present invention relates to an improved process for the production of conjugated polyunsaturated fatty acids (PUFA), preferably conjugated linoleic acid (CLA), using finely dispersed heterogeneous metal catalysts on a mesoporous support, in the absence of Hg. The present invention also relates to a method to increase the large microporosity and (optionally) the small mesoporosity of a zeolite, thus obtaining a modified zeolite having a large and highly accessible internal surface.