5457-57-8 Usage
General Description
(1R,2S)-2-sulfanylcyclopentanol is a chiral compound with the molecular formula C5H10OS. It is a cyclopentane derivative with a sulfhydryl group attached to the second carbon atom and an alcohol group attached to the first carbon atom. (1R,2S)-2-sulfanylcyclopentanol is commonly used as a synthetic intermediate in organic chemical reactions, especially in the production of pharmaceuticals and agrochemicals. The chiral nature of (1R,2S)-2-sulfanylcyclopentanol makes it an important starting material for the preparation of enantiomerically pure compounds, which are essential for drug development and asymmetric synthesis. Additionally, it can also be used as a building block in the synthesis of natural products and other complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 5457-57-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,5 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5457-57:
(6*5)+(5*4)+(4*5)+(3*7)+(2*5)+(1*7)=108
108 % 10 = 8
So 5457-57-8 is a valid CAS Registry Number.
5457-57-8Relevant articles and documents
Catalytic asymmetric synthesis of thiols
Monaco, Mattia Riccardo,Prvost, Sbastien,List, Benjamin
, p. 16982 - 16985 (2015/02/18)
The synthesis of enantiopure thiols is of significant interest for industrial and academic applications. However, direct asymmetric approaches to free thiols have previously been unknown. Here we describe a novel organocascade that is catalyzed by a confined chiral phosphoric acid and furnishes O-protected β-hydroxythiols with excellent enantioselectivities. The method relies on an asymmetric thiocarboxylysis of meso-epoxides, followed by an intramolecular trans-esterification reaction. By varying the reaction conditions, the intermediate thioesters can also be obtained chemoselectively and enantioselectively.