5472-71-9

Basic information

• Product Name: (4-MORPHOLINYLMETHYL)BENZOTRIAZOLE 97%&
• Synonyms: (4-MORPHOLINYLMETHYL)BENZOTRIAZOLE 97%&;1-(4-morpholinylmethyl)-1h-benzotriazol;1-(4-morpholinomethyl)-1H-benzotriazole;(4-MORPHOLINYLMETHYL)BENZOTRIAZOLE, 97%, MIXTURE OF BT1 AND BT2 ISOMERS;(4-morpholinylmethyl)benzotriazole, mixture of bt1 and bt2 isomers;1-(4-Morpholinylmethyl)-1H-benzotriazole
• CAS NO: 5472-71-9
• Molecular Formula: C₁₁H₁₄N₄O
• Molecular Weight: 218.25506
• EINECS: 226-813-2
• Mol File: 5472-71-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 104-107 °C(lit.)
• Boiling Point: 381.8°Cat760mmHg
• Flash Point: 184.7°C
• Appearance: /
• Density: 1.35g/cm³
• Vapor Pressure: 2.47E-14mmHg at 25°C
• Refractive Index: 1.575
• PKA: 4.63±0.10(Predicted)
• CAS DataBase Reference: (4-MORPHOLINYLMETHYL)BENZOTRIAZOLE 97%&(CAS DataBase Reference)
• NIST Chemistry Reference: (4-MORPHOLINYLMETHYL)BENZOTRIAZOLE 97%&(5472-71-9)
• EPA Substance Registry System: (4-MORPHOLINYLMETHYL)BENZOTRIAZOLE 97%&(5472-71-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 5472-71-9(Hazardous Substances Data)

Usage

General Description

(4-Morpholinylmethyl)benzotriazole, also known as UV-326, is a chemical compound widely used as a UV absorber in various polymers and coatings. It is a high-performance additive that provides protection against degradation caused by UV radiation. With a purity of 97%, it is considered a highly effective and versatile UV stabilizer that helps to extend the lifespan and improve the durability of various materials, such as plastics, rubber, and paints, that are exposed to sunlight. Additionally, it helps to prevent color fading, cracking, and other forms of degradation caused by UV exposure, making it a valuable component in many industrial and commercial applications.

InChI:InChI=1/C22H27FN2O4S/c1-3-29-20-8-6-19(7-9-20)25(16-22(26)24-14-12-17(2)13-15-24)30(27,28)21-10-4-18(23)5-11-21/h4-11,17H,3,12-16H2,1-2H3

Upstream product

• 110-91-8 morpholine 
• 95-14-7 1,2,3-Benzotriazole 
• 50-00-0 formaldehyd 
• 28539-02-8 1-Hydroxymethyl-1H-benzotriazole 
• 122668-94-4 N-<(benzotriazol-2-yl)methyl>morpholine 
• 111098-30-7 Benzotriazol-1-ylmethyl-(4-methyl-pyridin-2-yl)-amine 
• 54187-96-1 1-(chloromethyl)-1H-benzotriazole 

Downstream Products

• 147425-87-4 9-(1-Benzotriazol-1-yl-1-benzyl-3-morpholin-4-yl-propyl)-9H-carbazole 
• 147425-88-5 9-[1-Benzotriazol-1-yl-1-(4-methyl-benzyl)-3-morpholin-4-yl-propyl]-9H-carbazole 
• 147425-91-0 9-[1-Benzotriazol-1-yl-3-morpholin-4-yl-1-(phenyl-trimethylsilanyloxy-methyl)-propyl]-9H-carbazole 
• 147425-93-2 9-[1-Benzotriazol-1-yl-1-(cyclohexyl-trimethylsilanyloxy-methyl)-3-morpholin-4-yl-propyl]-9H-carbazole 
• 147425-92-1 9-[1-Benzotriazol-1-yl-3-morpholin-4-yl-1-(p-tolyl-trimethylsilanyloxy-methyl)-propyl]-9H-carbazole 
• 114460-92-3 1,3-diphenyl-3-morpholino-1-propyne 
• 1017-73-8 4-(3-phenyl-prop-2-ynyl)-morpholine 
• 20120-24-5 ethyl 3-morpholinopropionate 
• 72721-56-3 morpholinomethyl benzamide 
• 46346-12-7 N-(2-phenethyl)morpholine 
• 5379-88-4 N-morpholinyl-3-indolylmethylamine 
• 5379-86-2 4-((1H-indol-1-yl)methyl)morpholine 
• 33453-98-4 4-(2-methyl-2-nitropropyl)morpholine 

Relevant articles and documents

Synthesis and evaluation of hepatoprotective activity of some new mannich bases bearing benztriazole moiety

A series of benztriazoles bearing Mannich bases (2 -10) were synthesized from benztriazole by aminomethylation with formaldehyde and various substituted secondary amines. Titled compounds were synthesized by Mannich reaction and they were characterized by IR and 'HNMR spectroscopy. All these Mannich bases were screened for hepatoprotective activity on carbon tetrachloride induced liver damage in rats. Only compounds 4 (250 mg/kg) protected significantly the animals from carbon tetrachloride induced hepatotoxicity. Compound 4 N-morpholinyl methyl benztriazole exhibited significant activity comparable to that of standard drug silymarin.

Synthesis of novel α-amino-N-substituted thioacetimidates

-

Benzotriazol-1-ylmethylammonium Salts Synthesis and Reactivity

Benzotriazol-1-ylmethylamines on treatment with alkylating agents afford benzotriazol-1-ylmethylammonium salts, also available from reactions of chloromethylbenzotriazole with tertiary amines.In deuterated solvents under basic conditions the methylene protons of these salts exchange with deuterium.At elevated temperatures, an alkyl group substituent migrated from the ammonium center to the benzotriazolyl N-3.Reactions of the salts with Grignard reagents afforded various products arising from substitution of the ammonium moiety and/or from attack on the benzotriazolyl N-3 or on the benzenoid ring.