54885-66-4

Basic information

• Product Name: Z-GLY-D-PHE-OH
• Synonyms: Z-GLY-D-PHE-OH;Z-L-Gly-D-Phe-OH
• CAS NO: 54885-66-4
• Molecular Formula: C₁₉H₂₀N₂O₅
• Molecular Weight: 356.37
• Mol File: 54885-66-4.mol

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: Z-GLY-D-PHE-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-GLY-D-PHE-OH(54885-66-4)
• EPA Substance Registry System: Z-GLY-D-PHE-OH(54885-66-4)

Safety Data

• Hazardous Substances Data: 54885-66-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
Z-GLY-D-PHE-OH is used as a building block for the synthesis of larger peptide molecules, facilitating the development of novel pharmaceutical compounds with potential therapeutic applications.
Used in Enzyme Research:
Z-GLY-D-PHE-OH is used as a substrate for enzymes, enabling the study of enzymatic reactions and the exploration of enzyme mechanisms and specificity.
Used in Protein Structure and Function Studies:
Z-GLY-D-PHE-OH is used as a tool for investigating the structural and functional aspects of proteins, contributing to a deeper understanding of peptide-protein interactions.
Used in Drug Discovery and Development:
Z-GLY-D-PHE-OH is used as a template or mimic for naturally occurring peptides, potentially leading to the discovery of new drugs that can modulate biological pathways and treat various diseases.

Upstream product

• 501-53-1 benzyl chloroformate 
• 77987-49-6 benzyl 2-hydroxyethylcarbamate 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 21685-51-8 D-phenylalanine methyl ester 
• 73538-53-1 methyl cbz-glycyl-D-phenylalaninate 
• 116506-68-4 N-(N'-benzyloxycarbonylglycyl)-L-phenylalaninol 
• 15050-24-5 N-(benzyloxycarbonyl)glycyl chloride 
• 1795-96-6 D-phenylalanine ethyl ester 

Downstream Products

• 30189-49-2 L-carbobenzyloxyglycylphenylalanine N-benzylamide 
• 87784-04-1 2-((carbobenzyloxyamino)methyl)-4-benzyl-5-(N-benzyltrifluoroacetamido)oxazole 
• 30189-49-2 N-(N-benzyloxycarbonyl-glycyl)-phenylalanine benzylamide 
• 81308-82-9 glycyl-D-phenylalanyldodecylamide 
• 113266-24-3 Cbz-Gly-D-Phe-Val-OMe 
• 81308-84-1 carbobenzoxyglycyl-D-phenylalanylbis(2-chloroethyl)amine 
• 34258-14-5 glycyl-D-phenylalanine 
• 97811-94-4 Gly-D-Phe-L-Lys 
• 81308-79-4 carbobenzoxyglycyl-D-phenylalanyl-N-(2,2,2-trifluoroethyl)-n-dodecylamide 
• 75220-98-3 [((R)-1-Dodecylcarbamoyl-2-phenyl-ethylcarbamoyl)-methyl]-carbamic acid benzyl ester 

Relevant articles and documents

Enantioselective Synthesis of erythro-β-Hydroxy-L-histidine, the Pivotal Amino Acid of Bleomycin-Fe(II)-O2 Complex

erythro-β-Hydroxy-L-histidine, a novel amino acid constituent of bleomycin, has been synthesized enantioselectively via the reaction of (N-pyruvylideneglycyl-D-phenylalaninato)copper(II) with imidazole-4-carbaldehyde.

Amino alcohols as C-Terminal Protecting Groups in Peptide Synthesis

The synthesis of peptides using amino alcohols as C-terminal protecting groups is described.C-Terminal protection of amino acid could be accomplished by reduction of the terminal carboxyl group to a hydroxymethyl group, and regeneration of the carboxyl group could be achieved by Jones' oxidation.This method was applied to the formation of di- and tripeptides.