5520-79-6

Basic information

• Product Name: ethyl (4-acetylphenyl)carbamate
• Synonyms: carbamic acid, N-(4-acetylphenyl)-, ethyl ester
• CAS NO: 5520-79-6
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.2258
• Mol File: 5520-79-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 294.1°C at 760 mmHg
• Flash Point: 131.7°C
• Density: 1.171g/cm³
• Vapor Pressure: 0.00165mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: ethyl (4-acetylphenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (4-acetylphenyl)carbamate(5520-79-6)
• EPA Substance Registry System: ethyl (4-acetylphenyl)carbamate(5520-79-6)

Safety Data

• Hazardous Substances Data: 5520-79-6(Hazardous Substances Data)

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 99-92-3 p-aminobenzophenone 
• 62-53-3 aniline 
• 124-38-9 carbon dioxide 
• 75-03-6 ethyl iodide 
• 586-89-0 4-acetyl-benzoic acid 
• 153621-93-3 O-Ethyl S-(2,4,6-trinitrophenyl) thiocarbonate 
• 105-58-8 Diethyl carbonate 
• 64-17-5 ethanol 
• 114691-91-7 4-acetylbenzoyl azide 

Downstream Products

• 6324-80-7 NSC 31703 
• 82366-45-8 4-acetyl-2,6-dinitroaniline 
• 23598-69-8 3-(4-acetyl-phenyl)-5-prop-2-ynyloxymethyl-oxazolidin-2-one 
• 761412-32-2 (4-acetyl-2-nitro-phenyl)-carbamic acid ethyl ester 
• 5394-70-7 [4-(4-dimethylamino-trans-cinnamoyl)-phenyl]-carbamic acid ethyl ester 

Relevant articles and documents

Arylaminopropanone derivatives as potential cholinesterase inhibitors: Synthesis, docking study and biological evaluation

Neurodegenerative diseases in which the decrease of the acetylcholine is observed are growing worldwide. In the present study, a series of new arylaminopropanone derivatives with N-phenylcarbamate moiety (1-16) were prepared as potential acetylcholinesterase and butyrylcholinesterase inhibitors. In vitro enzyme assays were performed; the results are expressed as a percentage of inhibition and the IC50 values. The inhibitory activities were compared with reference drugs galantamine and rivastigmine showing piperidine derivatives (1-3) as the most potent. A possible mechanism of action for these compounds was determined from a molecular modelling study by using combined techniques of docking, molecular dynamics simulations and quantum mechanics calculations.

Synthesis and in vitro antimycobacterial activity of novel n-arylpiperazines containing an ethane-1,2-diyl connecting chain

Novel 1-(2-{3-/4-[(alkoxycarbonyl)amino]phenyl}-2-hydroxyethyl)-4-(2-fluorophenyl)-piperazin-1-ium chlorides (alkoxy = methoxy to butoxy; 8a-h) have been designed and synthesized through multistep reactions as a part of on-going research programme focused

SUBSTITUTED ANILINE DERIVATIVES

The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.