55216-11-0 Usage
Uses
Different sources of media describe the Uses of 55216-11-0 differently. You can refer to the following data:
1. Trimethyl-β-cyclodextrin (CAS# 55216-11-0) is β-cyclodextrin (C987830) derivative used to solubilize steroids in aqueous solution to increase their bioavailability.
2. Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC) techniques.In the determination of the analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).
3. Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC).In the determination of analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).
General Description
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a β-cyclodextrin derivative that finds potential use in pharmaceutical, food and cosmetic applications. Its attractive features include: the non-polar cavity desirable for its use as a molecular host for a wide range of molecules and its affinity for organic compounds in solution as well as crystalline phases.
Check Digit Verification of cas no
The CAS Registry Mumber 55216-11-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,2,1 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 55216-11:
(7*5)+(6*5)+(5*2)+(4*1)+(3*6)+(2*1)+(1*1)=100
100 % 10 = 0
So 55216-11-0 is a valid CAS Registry Number.
InChI:InChI=1/C63H112O35/c1-64-22-29-36-43(71-8)50(78-15)57(85-29)93-37-30(23-65-2)87-59(52(80-17)44(37)72-9)95-39-32(25-67-4)89-61(54(82-19)46(39)74-11)97-41-34(27-69-6)91-63(56(84-21)48(41)76-13)98-42-35(28-70-7)90-62(55(83-20)49(42)77-14)96-40-33(26-68-5)88-60(53(81-18)47(40)75-12)94-38-31(24-66-3)86-58(92-36)51(79-16)45(38)73-10/h29-63H,22-28H2,1-21H3/t29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43+,44+,45+,46+,47+,48+,49+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m1/s1
55216-11-0Relevant articles and documents
Synthesis of cyclodextrins with carboxylic acids at the secondary rim and an evaluation of their properties as chemzymes for glycoside hydrolysis
Zhou, You,Lindbaeck, Emil,Marinescu, Lavinia G.,Pedersen, Christian Marcus,Bols, Mikael
, p. 4063 - 4070 (2012)
Seven β-cyclodextrin-mono-, -di-or -tetra-O-acetic acids were prepared and investigated for their propertiesas catalysts of the hydrolysis of four nitrophenyl glycosides.
A facile synthesis of novel cyclodextrin derivatives incorporating one beta-(1,4)-glucosidic bond and their unique inclusion ability.
Kida, Toshiyuki,Kikuzawa, Akira,Nakatsuji, Yohji,Akashi, Mitsuru
, p. 3020 - 3021 (2003)
Novel cyclodextrin derivatives incorporating one (1,4)-glucosidic bond are easily synthesized in three steps from permethylated alpha- and beta-cyclodextrins, and such host molecules show inclusion selectivity for sodium m-nitrobenzoate over the corresponding p-isomer, in contrast to the cases of the parent permethylated alpha- and beta-cyclodextrins.
Xylylene Clips for the Topology-Guided Control of the Inclusion and Self-Assembling Properties of Cyclodextrins
Neva, Tania,Carmona, Thais,Benito, Juan M.,Przybylski, Cédric,Ortiz Mellet, Carmen,Mendicuti, Francisco,García Fernández, José M.
, p. 5588 - 5597 (2018)
The topology of β-cyclodextrin can be molded, from toroidal to ovoid basket-shaped, by the installation of an o- or m-xylylene moiety connecting two consecutive d-glucopyranosyl units through the secondary O-2(I) and O-3(II) positions. This strategy can be exploited advantageously to precast the cavity for preferential inclusion of globular or planar guests as well as to privilege dimeric or monomeric species in water solution.
Enhanced photodynamic therapy through supramolecular photosensitizers with an adamantyl-functionalized porphyrin and a cyclodextrin dimer
Xia, Lei,Wu, Jian,Huang, Baoxuan,Gao, Yun,Tian, Jia,Zhang, Weian
supporting information, p. 11134 - 11137 (2020/10/05)
A supramolecular photosensitizer was constructed using a tetra-adamantane-functionalized porphyrin and a dimer of permethyl-β-cyclodextrin through host-guest interaction and self-assembly. The porphyrin/cyclodextrin alternating structure of supramolecular