5527-94-6

Basic information

• Product Name: 3-Fluoro-4-chlorotoluene
• Synonyms: 2-FLUORO-4-METHYLCHLOROBENZENE;3-FLUORO-4-CHLORO TOLUENE;4-CHLORO-3-FLUOROTOLUENE;1-chloro-2-fluoro-4-methylbenzene;3-Fluoro-4-chlorotol
• CAS NO: 5527-94-6
• Molecular Formula: C₇H₆ClF
• Molecular Weight: 144.57
• Product Categories: Aromatic Halides (substituted);Halogen toluene;Chlorine Compounds;Fluorine Compounds
• Mol File: 5527-94-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 157-158°C
• Flash Point: 54.8 °C
• Appearance: colourless or light yellow liquid
• Density: 1,2 g/cm3
• Vapor Pressure: 2.32mmHg at 25°C
• Refractive Index: 1.502
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-Fluoro-4-chlorotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-4-chlorotoluene(5527-94-6)
• EPA Substance Registry System: 3-Fluoro-4-chlorotoluene(5527-94-6)

Safety Data

• Hazard Codes: Xi,F
• Statements: 36/37/38-10
• Safety Statements: 26-36/37/39-36-16
• RIDADR: 3265
• HazardClass: 3
• Hazardous Substances Data: 5527-94-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6ClF/c1-5-2-3-6(8)7(9)4-5/h2-4H,1H3

Upstream product

• 86522-86-3 4,6-dichloro-3-fluoro-toluene 
• 352-70-5 m-Fluorotoluene 
• 108-44-1 1-amino-3-methylbenzene 
• 79-35-6 1,1'-dichloro-2,2'-difluoroethene 
• 78-79-5 isoprene 
• 4265-28-5 2-chloro-1,1,2-trifluoro-3-methyl-3-vinylcyclobutane 

Downstream Products

• 403-17-8 4-chloro-3-fluorobenzoic acid 
• 64248-62-0 3,4-Difluorobenzonitrile 
• 1242339-40-7 5-chloro-4-fluoro-2-methylbenzenesulfonyl chloride 
• 122064-09-9 4-(2-chloro-5-methylphenyl)morpholine 
• 1422510-55-1 3-chloro-2-fluoro-6-methylbenzaldehyde 
• 118664-99-6 1-chloro-2-fluoro-4-methyl-5-nitrobenzene 

Relevant articles and documents

Preparation method of 4-halogenated-3-fluorotoluene

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of 4-halogenated -3-fluorotoluene. The preparation reaction of 4-halogenated -3-fluorotolueneshown as a formula (I) is shown in the specification. According to the method, halogenation reaction is conducted on 3-fluorotoluene serving as an initial raw material to obtain a halide, and hydrogenreduction is conducted to obtain a compound shown in the general formula (I), wherein X is chlorine or bromine. According to the method, 3-fluorotoluene is used as a raw material, and a target product is obtained through two-step reactions of halogenation and reduction. The reaction steps in the process are few; diazotization, nitrification and other reactions are avoided, and the reaction safetyis high.

Continuous production method for industrially preparing 2,3-difluorobenzotrifluoride and 3,4-difluorobenzonitrile

The invention discloses a continuous production method for industrially preparing 2,3-difluorobenzotrifluoride and 3,4-difluorobenzonitrile. The preparation process of the 2,3-difluorobenzotrifluoride comprises the preparation step of an intermediate raw material for benzene sulfonamide and benzenesulfonylurea herbicides, and the preparation process of the 3,4-difluorobenzonitrile comprises the preparation step of a cthalofop-butyl intermediate raw material. The method is suitable for industrial production; and compared with the prior art, the method has the advantages of low cost, high production method and less pollution.