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55305-43-6

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55305-43-6 Usage

Uses

N-Cyano-N-phenyl-p-toluenesulfonamide is a useful research reactant for the synthesis of synthesis of 1,?2,?4-?triazol-?3-?imines through stepwise cycloaddition.

Check Digit Verification of cas no

The CAS Registry Mumber 55305-43-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,3,0 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 55305-43:
(7*5)+(6*5)+(5*3)+(4*0)+(3*5)+(2*4)+(1*3)=106
106 % 10 = 6
So 55305-43-6 is a valid CAS Registry Number.

55305-43-6Relevant articles and documents

Rhodium(III)-catalyzed cyanation of vinylic C-H bonds: N-cyano-N-phenyl-p-toluenesulfonamide as a cyanation reagent

Su, Wei,Gong, Tian-Jun,Xiao, Bin,Fu, Yao

, p. 11848 - 11851 (2015)

Rh(iii)-catalyzed direct vinylic C-H cyanation reaction has been developed as a practical method for the synthesis of alkenyl nitriles. N-Cyano-N-phenyl-p-methylbenzenesulfonamide (NCTS), a user-friendly cyanation reagent, was used in the transformation.

COMPOUNDS TARGETING PRMT5

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Paragraph 0306, (2021/10/11)

Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Ni-Catalyzed Reductive Arylcyanation of Alkenes

Li, Hengxu,Chen, Jiachang,Dong, Jueqi,Kong, Wangqing

supporting information, p. 6466 - 6470 (2021/08/23)

We disclose a Ni-catalyzed reductive arylcyanation of alkene using environmentally benign and nontoxic organo cyanating reagent N-cyano-N-phenyl-p-toluenesulfonamide. This reaction provides a new method for the rapid synthesis of cyano-substituted oxindoles and isoquinoline-1,3-diones and features high functional group tolerance. In addition, an enantioselective version was developed for the construction of enantiomerically enriched 3-cyanomethyl oxindole. This method has also been applied to the synthesis of natural alkaloids (+)-esermethole and (+)-physostigmine.

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