55441-71-9 Usage
General Description
9-Methyluric acid, also known as 1,3,7-trimethyluric acid, is a chemical compound found in the human body as a metabolite of caffeine. It is formed when caffeine is broken down in the liver by an enzyme called cytochrome P450 1A2. 9-Methyluric acid is excreted in urine and is a minor component compared to other caffeine metabolites. It has been studied for its potential as a biomarker for caffeine intake and metabolism, as well as its role in the pharmacokinetics of caffeine. Additionally, 9-methyluric acid has been identified as a potential marker for certain metabolic disorders. Further research is needed to fully understand the biological significance and implications of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 55441-71-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,4,4 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 55441-71:
(7*5)+(6*5)+(5*4)+(4*4)+(3*1)+(2*7)+(1*1)=119
119 % 10 = 9
So 55441-71-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N4O3/c1-10-3-2(7-6(10)13)4(11)9-5(12)8-3/h1H3,(H,7,13)(H2,8,9,11,12)
55441-71-9Relevant articles and documents
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Falconer,Gulland
, p. 1369 (1939)
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Purines. XIV [1]. Synthesis and properties of 8-nitroxanthine and its N- methyl derivatives
Mosselhi,Pfleiderer
, p. 1221 - 1228 (2007/10/02)
Xanthine (1) and its N-methyl derivatives 2-16 have been nitrated to the corresponding 8-nitro derivatives 17-32 under different reaction conditions. Nitration in glacial acetic acid with nitric acid works well with the N-7 unsubstituted and some of the 9-methylxanthines, respectively, whereas the 7- methylxanthine derivatives react best with nitronium tetrafluoroborate in sulfolane or glacial acetic acid. The 8-nitro group can be displaced nucleophilically to form 8-chloro-, 33, 34, 8-ethoxy-, 35, 36, and uric acid derivatives 37-40, respectively. The newly synthesized 8-nitroxanthines have been characterized by elemental analyses, pK-determinations and uv and 1H- nmr spectra.
