556-21-8

Basic information

• Product Name: 4-(Methylamino)benzaldehyde
• Synonyms: 4-(Methylamino)benzaldehyde
• CAS NO: 556-21-8
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.16
• Mol File: 556-21-8.mol
• Article Data: 26

Chemical Properties

• Melting Point: 56-57 °C
• Boiling Point: 185-187 °C(Press: 15 Torr)
• Appearance: /
• Density: 1.121±0.06 g/cm3(Predicted)
• PKA: 1.34±0.12(Predicted)
• CAS DataBase Reference: 4-(Methylamino)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Methylamino)benzaldehyde(556-21-8)
• EPA Substance Registry System: 4-(Methylamino)benzaldehyde(556-21-8)

Safety Data

• Hazardous Substances Data: 556-21-8(Hazardous Substances Data)

Usage

General Description

4-(Methylamino)benzaldehyde, also known as p-(Methylamino)benzaldehyde, is a chemical compound with the molecular formula C8H9NO. It is an aromatic aldehyde with a benzene ring substituted with a methylamino group and an aldehyde functional group. 4-(Methylamino)benzaldehyde is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds. It has been reported to possess antimicrobial and anti-inflammatory properties, making it a potential candidate for medical and pharmaceutical applications. Additionally, 4-(Methylamino)benzaldehyde is used in the synthesis of dyes, perfumes, and flavors due to its aromatic properties. However, it is important to handle this chemical with care, as it can be irritating to the skin and eyes.

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 74-89-5 methylamine 
• 1122-91-4 4-bromo-benzaldehyde 
• 3717-21-3 p-methoxyl benzaldoxime 
• 1665-95-8 N-(4-formylphenyl)-N,4-dimethylbenzenesulfonamide 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 121-69-7 N,N-dimethyl-aniline 
• 60577-34-6 p-iodo-N-methylaniline 
• 82102-37-2 9-methyl-9H-fluorene-9-carbonyl chloride 
• 15875-74-8 N-(4-methoxybenzylidene)-2-methylpropan-2-amine 
• 18358-63-9 methyl 4-(N-methyl)aminobenzoate 
• 79865-85-3 p-methoxybenzylidenedimethylimmonium iodide 
• 181819-75-0 (4-(methylamino)phenyl)methanol 

Downstream Products

• 61930-50-5 {4-[(4,5-Diphenyl-oxazol-2-yl)-hydrazonomethyl]-phenyl}-methyl-amine 
• 2769-09-7 1-<4-Methylamino-benzyliden>-cyclopentadien 
• 1396341-13-1 (E)-3-(4-(methylamino)benzylidene)-5-bromoindolin-2-one 
• 1396341-18-6 (Z)-2-(4-(methylamino)benzylidene)-1-acetyl-5-bromoindolin-3-one 
• 1224714-00-4 (E)-4-(3,5-dimethoxystyryl)-N-methylaniline 
• 439858-28-3 (4-(benzo[d]thiazole-2′-yl)-N-methylaniline) 
• 1620563-10-1 C₁₈H₁₅N₃O 

Relevant articles and documents

Highly Efficient Binuclear Copper-catalyzed Oxidation of N,N-Dimethylanilines with O2

A binuclear copper-salicylate complex, [Cu(Sal)2(NCMe)]2 (Sal=salicylate), was found to be an active catalyst for the oxidation of N,N-dimethylanilines by O2, affording the corresponding N-methyl-N-phenylformamides as major products. The reactions were carried out with a O2 balloon and the S/C (substrate/catalyst ratio) of the model reaction could be up to 1×105, providing a practical and highly efficient catalytic protocol for accessing N-methyl-N-phenylformamides.

USE OF BENZOTHIAZOLE AMPHIPHILES FOR TREATING TRAUMATIC BRAIN INJURY

The present invention is directed to methods of reducing symptoms of traumatic brain injury in patients by administering a therapeutically effective amount of a benzothiazole amphiphile compound to a patient suffering from a traumatic brain injury within 0 to 72 hours of incurring the injury.

Dichlorophenylacrylonitriles as AhR Ligands That Display Selective Breast Cancer Cytotoxicity in vitro

Knoevenagel condensation of 3,4-dichloro- and 2,6-dichlorophenylacetonitriles gave a library of dichlorophenylacrylonitriles. Our leads (Z)-2-(3,4-dichlorophenyl)-3-(1H-pyrrol-2-yl)acrylonitrile (5) and (Z)-2-(3,4-dichlorophenyl)-3-(4-nitrophenyl)acryloni