55676-22-7

Basic information

• Product Name: 2-Chloro-5-acetylpyridine
• Synonyms: 1-(6-CHLORO-3-PYRIDINYL)-1-ETHANONE;1-(6-CHLOROPYRIDIN-3-YL)ETHANONE;2-CHLORO-5-ACETYLPYRIDINE;6-CHLORO-3-ACETYLPYRIDINE;1-(6-CHLOROPYRIDIN-3-YL)ETHANONE ,97%;1-(6-Chloropyridin-3-yl)ethan-1-one;5-Acetyl-2-chloropyridine;3-Acetyl-6-chloropyridine
• CAS NO: 55676-22-7
• Molecular Formula: C₇H₆ClNO
• Molecular Weight: 155.58
• Product Categories: Heterocycle-Pyridine series
• Mol File: 55676-22-7.mol
• Article Data: 35

Chemical Properties

• Melting Point: 98 °C
• Boiling Point: 280.46 °C at 760 mmHg
• Flash Point: 123.418 °C
• Appearance: /
• Density: 1.233 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -2.14±0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-5-acetylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-acetylpyridine(55676-22-7)
• EPA Substance Registry System: 2-Chloro-5-acetylpyridine(55676-22-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 55676-22-7(Hazardous Substances Data)

Usage

General Description

2-Chloro-5-acetylpyridine, also known as 5-Acetyl-2-chloropyridine, is a chemical compound with the molecular formula C7H6ClNO. It is a chlorinated derivative of pyridine, an aromatic heterocyclic compound. 2-Chloro-5-acetylpyridine is a clear, colorless liquid with a sweet, fruity odor. It is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Due to its reactivity and potential health hazards, it is important to handle 2-Chloro-5-acetylpyridine with proper safety precautions in a controlled laboratory environment.

Upstream product

• 58757-38-3 6-Chloronicotinoyl chloride 
• 67-68-5 dimethyl sulfoxide 
• 4684-94-0 6-chloropicolinic acid 
• 75-16-1 methylmagnesium bromide 
• 431-03-8 dimethylglyoxal 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 149281-42-5 6-chloro-N-methoxy-N-methylpyridine-3-carboxamide 
• 53939-30-3 5-bromo-2-chloropyridine 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 216317-64-5 ethyl 3-(6-chloropyridin-3-yl)-3-oxopropanoate 
• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 
• 108-59-8 malonic acid dimethyl ester 
• 33252-28-7 6-chloronicotinonitrile 
• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 

Downstream Products

• 265107-43-5 1-(6-morpholin-4-yl-pyridin-3-yl)-ethanone 
• 265107-45-7 1-(6-pyrrolidin-1-yl-pyridin-3-yl)-ethanone 
• 373604-52-5 6-amino-4-(3-bromo-phenyl)-6'-chloro-[2,3']bipyridinyl-5-carbonitrile 
• 68700-91-4 2-chloro-5-(1-hydroxy-1-methylethyl)pyridine 
• 1211536-35-4 1-(6-ethylpyridin-3-yl)-ethanone 
• 1384276-62-3 methyl 2-((5-(1-(((4-(trifluoromethyl)benzyl)oxy)imino)ethyl)pyridin-2-yl)oxy)acetate 
• 1384275-68-6 2-((5-(1-(((4-(trifluoromethyl)benzyl)oxy)imino)ethyl)pyridin-2-yl)oxy)acetic acid 

Relevant articles and documents

Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions

A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.

INHIBITORS OF MUTANT ISOCITRATE DEHYDROGENASES AND COMPOSITIONS AND METHODS THEREOF

The invention provides novel chemical compounds useful for treating cancer, or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.

High-activity iminophenylacetate compound, preparation method and applications thereof

The present invention belongs to the field of pesticides, and particularly relates to a high-activity iminophenylacetate compound, a preparation method and applications thereof. According to the present invention, the research of novel methoxy acrylate compounds is performed, a pyridine aryl ether structure is introduced into the structure of the novel methoxy acrylate compound, the research of the new compound structures is expanded, and the high-activity iminophenylacetate compound is found; and the compound has the bioactivity equal to azoxystrobin and trifloxystrobin, provides good effects on most pathogenic bacteria, especially provides significant prevention and treatment effects on Sclerotinia sclerotiorum bacterial, and is effective at a low doses.