56663-76-4

Basic information

• Product Name: 2,2-DIMETHYL-BUT-3-YNOIC ACID
• Synonyms: AKOS 91882;2,2-DIMETHYL-BUT-3-YNOIC ACID;2,2-DiMethyl-but-3-ynoic acidI;3-Butynoic acid, 2,2-diMethyl-;56663-76-4
• CAS NO: 56663-76-4
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.12652
• Mol File: 56663-76-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 188.246 °C at 760 mmHg
• Flash Point: 85.6 °C
• Appearance: /
• Density: 1.057 g/cm³
• Storage Temp.: 2-8°C
• PKA: 3.62±0.10(Predicted)
• Water Solubility: at 25 deg C (mg/L): 2.67e+004
• CAS DataBase Reference: 2,2-DIMETHYL-BUT-3-YNOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHYL-BUT-3-YNOIC ACID(56663-76-4)
• EPA Substance Registry System: 2,2-DIMETHYL-BUT-3-YNOIC ACID(56663-76-4)

Safety Data

• RIDADR: 3265
• HazardClass: 8
• PackingGroup: Ⅱ
• Hazardous Substances Data: 56663-76-4(Hazardous Substances Data)

Usage

General Description

2,2-Dimethyl-but-3-ynoic acid is a chemical compound with the molecular formula C6H8O2. It is an organic compound that belongs to the class of carboxylic acids. The compound is characterized by a butynoic acid structure with a methyl group attached to both the second and second-to-last carbon atom, hence the name 2,2-dimethyl-but-3-ynoic acid. It is a white crystalline solid at room temperature and is primarily used as an intermediate in organic synthesis and in the production of pharmaceuticals and other fine chemicals. It is also commonly used in research laboratories as a building block in the synthesis of various organic compounds.

Upstream product

• 5272-33-3 2-methyl-4-(trimethylsilyl)but-3-yn-2-ol 

Downstream Products

• 114081-07-1 2,2-dimethyl-but-3-ynoyl chloride 
• 95924-34-8 2,2-dimethyl-3-butynoic acid methyl ester 
• 204588-77-2 2,2-dimethyl-3-butynoic acid benzyl ester 
• 952665-09-7 methyl 4-(2-butyramido-5-nitrophenyl)-2,2-dimethylbut-3-ynoate 
• 952665-08-6 methyl 4-(2-amino-5-nitrophenyl)-2,2-dimethylbut-3-ynoate 
• 1259034-42-8 (S)-3-((S)-1-(4-(4-(azetidin-1-yl)-3,3-dimethyl-4-oxobut-1-ynyl)phenyl)ethyl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one 
• 188990-86-5 4-(6-Benzyloxy-pyridin-2-yl)-2,2-dimethyl-but-3-ynoic acid methyl ester 
• 188990-87-6 4-(6-Benzyloxy-pyridin-2-yl)-2,2-dimethyl-but-3-ynoic acid 
• 204588-86-3 1-[7-[3-(benzyloxycarbonyl)-3,3-dimethyl-1-propynyl]-1,2,3,4-tetrahydro-1(R,S)-naphthyl]-2,3,4-tri-O-acetyl-α-L-fucopyranose 
• 204588-80-7 1-[7-[3-(benzyloxycarbonyl)-3,3-dimethyl-1-propynyl]-1,2,3,4-tetrahydro-1(R,S)-naphthyl]-2,3,4-tri-O-benzyl-α-L-fucopyranose 
• 204588-78-3 7-[3-(benzyloxycarbonyl)-3,3-dimethyl-1-propynyl]-1,2,3,4-tetrahydronaphthalen-1-one 
• 204588-79-4 7-[3-(benzyloxycarbonyl)-3,3-dimethyl-1-propynyl]-1,2,3,4-tetrahydro-1(R,S)-naphthol 

Relevant articles and documents

KINASE INHIBITORS

There are provided compounds of formula (I), (Formula (I)) wherein R1 to R5, X1, X2, Ar, L, E, A, A1, G and G1 have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.