56672-63-0

Basic information

• Product Name: Cbz-L-arginine hydrochloride
• Synonyms: CBZ-L-ARGININE HCL;N-ALPHA-CBZ-L-ARGININE HYDROCHLORIDE;N-ALPHA-CARBOBENZOXY-L-ARGININE HYDROCHLORIDE;N-ALPHA-BENZYLOXYCARBONYL-L-ARGININE HYDROCHLORIDE;N-ALPHA-BENZYLOXYCARBONYL-L-ARGININE HYDROCHLORIDE SALT;N-ALPHA-Z-L-ARGININE HYDROCHLORIDE;N(ALPHA)-Z-L-ARGININE HCL;Z-L-ARGININE HYDROCHLORIDE
• CAS NO: 56672-63-0
• Molecular Formula: C₁₄H₂₀N₄O₄*ClH
• Molecular Weight: 344.79
• Product Categories: Amino Acid Derivatives;Arginine [Arg, R]
• Mol File: 56672-63-0.mol

Chemical Properties

• Boiling Point: 574 °C at 760 mmHg
• Flash Point: 301 °C
• Appearance: /
• Density: 1.33g/cm3
• Refractive Index: 1.594
• Storage Temp.: Store at RT.
• CAS DataBase Reference: Cbz-L-arginine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-L-arginine hydrochloride(56672-63-0)
• EPA Substance Registry System: Cbz-L-arginine hydrochloride(56672-63-0)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 56672-63-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
Cbz-L-arginine hydrochloride is used as a pharmaceutical intermediate for the synthesis of various drugs. Its stability and reactivity make it an ideal candidate for the development of new therapeutic agents.
Used in Drug Delivery Systems:
Cbz-L-arginine hydrochloride is employed as a component in drug delivery systems, where its modified structure can enhance the solubility, stability, and bioavailability of therapeutic agents, improving their efficacy and safety.
Used in Research and Development:
Cbz-L-arginine hydrochloride is used as a research tool in the study of amino acid chemistry and peptide synthesis. Its unique properties allow scientists to explore new methods and techniques in the development of novel compounds and therapeutic strategies.
Used in Biochemical Research:
In the field of biochemical research, Cbz-L-arginine hydrochloride is utilized to investigate the role of L-arginine in various biological processes and its potential applications in treating diseases. Its modified structure provides insights into the interactions between amino acids and other biomolecules, contributing to a deeper understanding of biological systems.

InChI:InChI=1/C14H20N4O4/c15-13(16)17-8-4-7-11(12(19)20)18-14(21)22-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,18,21)(H,19,20)(H4,15,16,17)

Upstream product

• 112-53-8 1-dodecyl alcohol 
• 5134-44-1 Nα-benzyloxycarbonyl-arginine methyl ester hydrochloride 
• 124-22-1 n-Dodecylamine 

Downstream Products

• 5134-44-1 Nα-benzyloxycarbonyl-arginine methyl ester hydrochloride 

Relevant articles and documents

Interaction of arginine-based cationic surfactants with lipid membranes. An experimental and molecular simulation study

The effect of two arginine-based cationic surfactants, arginine N-lauroyl amide dihydrochloride and arginine O-lauroyl ester dihydrochloride, upon dipalmitoylphosphatidylcholine liposomes, is addressed in this work. Some aspects concerning the synthesis of these surfactants are also presented in some detail. Differential scanning calorimetry, as well as fluorescence anisotropy using several probes, is used to assess the relative effects on the lipid model membranes. In spite of the structural similarity among these molecules, which differ only by the group that connects the polar head to the tail, experimental results suggest differences in their behavior. Molecular dynamics simulation provides significant insight into the molecular mechanism that governs this interaction. A rationale is provided in terms of lipid-surfactant hydrogen bonding and the consequent positioning of the surfactant molecule within the bilayer.

Synthesis and biological properties of dicationic arginine-diglycerides

A novel family of dicationic arginine-diglyceride surfactants, 1,2-diacyl-3-O-(L-arginyl)-rac-glycerol·2HCl (XXR) with alkyl chain lengths in the range of C8-C14 was prepared. These new surfactants can be regarded as analogues of lecithins. They have two hydrophobic tails of identical fatty acid chains attached to the glycerol through ester bonds and a dicationic polar head from arginine instead of the zwitterionic on the lecithins. These new compounds can be classified as multifunctional surfactants with self-aggregation behaviour comparable to that of short-chain lecithins. They have antimicrobial activity similar to that of the conventional cationic surfactants and are as harmless as amphoteric betaines.