56691-80-6

Basic information

• Product Name: Benzene, [(3,7-dimethyl-2,6-octadienyl)sulfonyl]-, (E)-
• Synonyms: (E)-1-benzenesulfonyl-3,7-dimethylocta-2,6-diene;3,7-dimethyl-1-(phenylsulfonyl)-2E,6-octadiene;3,7-dimethyl-2E,6-octadien-1-phenyl sulphone;(3,7-dimethylocta-2,6-diene-1-sulfonyl)benzene;3,7-dimethyl-1-(phenylsulfonyl)-2(E),6(E)-octadiene;(E)- (3,7-dimethylocta-2,6-diene-1-sulfonyl)benzene
• CAS NO: 56691-80-6
• Molecular Formula: C16H22O2S
• Molecular Weight: 278.415
• Mol File: 56691-80-6.mol
• Article Data: 40

Chemical Properties

• CAS DataBase Reference: Benzene, [(3,7-dimethyl-2,6-octadienyl)sulfonyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(3,7-dimethyl-2,6-octadienyl)sulfonyl]-, (E)-(56691-80-6)
• EPA Substance Registry System: Benzene, [(3,7-dimethyl-2,6-octadienyl)sulfonyl]-, (E)-(56691-80-6)

Safety Data

• Hazardous Substances Data: 56691-80-6(Hazardous Substances Data)

Upstream product

• 106-24-1 Geraniol 
• 873-55-2 sodium benzenesulfonate 
• 106-25-2 Nerol 
• 115-95-7 linalool acetate 
• 6138-90-5 trans-geranyl bromide 
• 515-42-4 sodium phenylsulfonate 
• 35162-74-4 geranyl phenyl sulfide 
• 5389-87-7 1-chloro-3,7-dimethylocta-2,6-diene 
• 78-70-6 3,7-dimethylocta-1,6-dien-3-ol 
• 624-15-7 geraniol 
• 1175539-95-3 3,7-dimethylocta-1,6-dien-3-yl isobutyl carbonate 
• 85217-72-7 geranyl methyl carbonate 
• 85217-73-8 (Z)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate 
• 25932-11-0 benzenesulfinic acid sodium dihydrate 

Downstream Products

• 116059-49-5 (6E,10E)-2,6,11,15-tetramethyl-9-(phenylsulfonyl)hexadeca-2,6,10,14-tetraen-8-ol 
• 128329-34-0 (6E,2R,3S,5RS)-5-(phenylsulfonyl)-3,7,11-trimethyl-6,10-dodecadiene-2,3-diol 
• 134600-25-2 1-vinyl-1-methyl-3-(4',8'-dimethyl-3'E,7'-nonadienyl)cyclohex-3-ene 
• 77547-15-0 (2E,6E)-8-((1R,3R)-3-Benzenesulfonylmethyl-4-chloro-2,2,4-trimethyl-cyclohexyl)-2,6-dimethyl-octa-2,6-dienoic acid methyl ester 
• 77547-16-1 (2E,6E)-8-((1S,5S)-5-Benzenesulfonylmethyl-4,6,6-trimethyl-cyclohex-3-enyl)-2,6-dimethyl-octa-2,6-dienoic acid methyl ester 
• 77547-16-1 (2E,6E)-8-((1R,5S)-5-Benzenesulfonylmethyl-4,6,6-trimethyl-cyclohex-3-enyl)-2,6-dimethyl-octa-2,6-dienoic acid methyl ester 
• 19945-61-0 (E)-4,8-dimethylnona-1,3,7-triene 
• 79421-94-6 ((E)-6-Chloro-3,7-dimethyl-octa-2,7-diene-1-sulfonyl)-benzene 
• 74832-85-2 6,7-oxido-3,7-dimethyl-1-(benzenesulfonyl)-(2E)-octene 
• 132969-44-9 3-Bromo-2,6-dimethyl-8-(phenylsulfonyl)-6(E)-octen-2-ol 
• 123086-03-3 (4E)-4-methyl-6-phenylsulfonyl-4-hexenal 
• 333970-19-7 2-((E)-(2S,3S)-4-Benzenesulfonyl-2,3,6,10-tetramethyl-undeca-5,9-dienyl)-[1,3]dioxolane 
• 56691-71-5 α-cyclogeranylphenylsulfone 
• 56691-74-8 {[(2,6,6-trimethyl-1-cyclohexen-1-yl)methyl]sulfonyl}benzene 

Relevant articles and documents

Synthesis from geraniol of (2E,6E,10E,14E)-16-hydroxygeranylgeraniol and some of its derivatives

Several α,ω-bifunctional derivatives of E,E,E-geranylgeraniol were prepared via convergent synthesis starting with geraniol (8), which was converted in three steps into the tetrahydropyranyl ether of 8-chlorogeraniol (9) and 8-hydroxygeranylphenylsulfone (10). Combination of synthons 9 and 10 with subsequent reductive removal of the phenylsulfonyl group produced the tetrahydropyranyl ether of ω-hydroxygeranylgeraniol (5), hydrolysis of which gave exclusively trans-ω-hydroxygeranylgeraniol (1). Derivatives 5-7 of geranylgeraniol were synthesized using standard methods.

CHINONE-, HYDROCHINOME- AND NAPHTHOCHINONE-ANALOGUES OF VATIQUIONE FOR TREATMENT OF MITOCHONDRIAL DISORDER DISEASES

The disclosure provides therapeutic compositions (i.e., therapeutic agents) and methods of preventing or treating Friedreich's ataxia in a mammalian subject, reducing risk factors, signs and/or symptoms associated with Friedreich's ataxia (e.g. Complex I deficiency), and/or reducing the likelihood or severity of Friedreich's ataxia. The disclosure further provides novel intermediates for the production of said therapeutic compositions and related reduced versions of said therapeutic compositions, which reduce forms may also be used as therapeutic agents (or prodrugs of the therapeutic agent(s)).

Methyl-Shifted Farnesyldiphosphate Derivatives Are Substrates for Sesquiterpene Cyclases

New sesquiterpene backbones are accessible after biotransformation of presilphiperfolan-8β-ol synthase (BcBOT2), a fungal sesquiterpene synthase, with non-natural farnesyldiphosphates in which methyl groups are shifted by one position toward the diphosphate terminus. One of the macrocycles formed, a new germacrene A derivative, undergoes a Cope rearrangement to iso-β-elemene. Three of the new terpenoids show olfactoric properties that range from an intense peppery note to a citrus, ozone-like, and fruity scent.