56734-74-8Relevant articles and documents
"Pseudo-Cationic" Trifluoromethylation of Enol Esters with Sodium Trifluoromethanesulfinate.
Langlois, Bernard R.,Laurent, Eliane,Roidot, Nathalie
, p. 1291 - 1294 (1992)
Enol esters are converted into corresponding trifluoromethylated ketones and/or enol esters with sodium trifluoromethanesulfinate and t-butyl hydroperoxide in the presence of catalytic amounts of Cu(II). Key Words: trifluoromethylation; enol esters; sodiu
Csp3-H Trifluoromethylation of Unactivated Aliphatic Systems
He, Jiachen,Nguyen, Truong N.,Guo, Shuo,Cook, Silas P.
supporting information, p. 702 - 705 (2021/02/01)
A straightforward method for the undirected trifluoromethylation of unactivated methylene units was developed. The reaction proceeds in aqueous acetonitrile with Grushin's reagent, bpyCu(CF3)3, under broad-spectrum white-light irradiation. The trifluoromethylation tolerates a wide range of functional groups including ketones, esters, nitriles, amides, alcohols, and carboxylic acids. The C-H cleavage step is performed via intermolecular H atom abstraction, and the selectivities across a range of methylene units are reported. Mechanistic studies offer a general reaction coordinate for the overall transformation.
Radical Desulfur-Fragmentation and Reconstruction of Enol Triflates: Facile Access to α-Trifluoromethyl Ketones
Su, Xiaolong,Huang, Honggui,Yuan, Yaofeng,Li, Yi
, p. 1338 - 1341 (2017/01/24)
We report an efficient oxidative radical desulfur-fragmentation and reconstruction of enol triflates for the synthesis of α-CF3ketones. Preliminary mechanistic studies disclosed that oxidative fragmentation to release a CF3radical fr
