56862-41-0

Basic information

• Product Name: Benzenemethanamine, N-(1,1-dimethyl-2-propynyl)-
• CAS NO: 56862-41-0
• Molecular Formula: C12H15N
• Molecular Weight: 173.258
• Mol File: 56862-41-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(1,1-dimethyl-2-propynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(1,1-dimethyl-2-propynyl)-(56862-41-0)
• EPA Substance Registry System: Benzenemethanamine, N-(1,1-dimethyl-2-propynyl)-(56862-41-0)

Safety Data

• Hazardous Substances Data: 56862-41-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 2978-58-7 1,1-dimethylprop-3-ynylamine 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 100-44-7 benzyl chloride 
• 1604-29-1 1,1-dimethyl-2-propynyl acetate 
• 100-46-9 benzylamine 
• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 6214-31-9 3-bromo-3-methylbut-1-yne 

Relevant articles and documents

BTK Inhibitors and uses thereof

The invention discloses a bruton's tyrosine kinase (BTK) inhibitor and use thereof. Specifically, the invention provides heteroaromatic compounds or stereoisomers, geometrical isomers, tautomers, racemates, nitrogen oxides, hydrates, solvates, metabolites and pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the heteroaromatic compounds; the invention also discloses use of the heteroaromatic compounds or the pharmaceutical compositions containing the heteroaromatic compounds in preparation of medicines; the medicines can be used for treating autoimmune diseases, inflammatory diseases or proliferative diseases.

Construction of the Oxazolidinone Framework from Propargylamine and CO2 in Air at Ambient Temperature: Catalytic Effect of a Gold Complex Featuring an L2/Z-Type Ligand

The metal-catalyzed carboxylation of propargylamines with aerial CO2 at room temperature to form 5-methyleneoxazolidin-2-one derivatives has been developed. In this reaction, the catalyst [Au(dpbF)]X featuring a Z-type ligand gave the best results, presumably due to the σ-acceptance of the borane atom.

Silver-catalyzed three-component reaction of propargylic amines, carbon dioxide, and N-iodosuccinimide for stereoselective preparation of (E)-iodovinyloxazolidinones

The silver-catalyzed three-component reaction of propargylic amines, carbon dioxide, and N-iodosuccinimide for the stereoselective synthesis of (E)-iodovinyloxazolidinones was developed. The silver-catalytic system could be applied to various propargylic amines to afford the corresponding iodovinyloxazolidinones in high yields. The structure of the oxazolidinone was confirmed by X-ray structure analysis to be the Eisomer for the geometry of the exo-olefin. The silver-catalyzed cyclization and replacement of silver with the iodine group in the intermediate were thought to be crucial steps.