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570401-65-9

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570401-65-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 570401-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,0,4,0 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 570401-65:
(8*5)+(7*7)+(6*0)+(5*4)+(4*0)+(3*1)+(2*6)+(1*5)=129
129 % 10 = 9
So 570401-65-9 is a valid CAS Registry Number.

570401-65-9Downstream Products

570401-65-9Relevant articles and documents

Diorganotin(IV) derivatives of arylhydroxamic acids: Synthesis, properties and antitumor activity

Li, Qingshan,Guedes Da Silva, M. Fátima C.,Jinghua, Zhao,Pombeiro, Armando J.L.

, p. 4584 - 4591 (2007/10/03)

Series of diorganotin(IV) complexes of para-substituted benzohydroxamic acid, [R2SnL2] and [R2Sn(L)]2O, have been prepared and characterized. Their in vitro antitumor activity against a series of human tumor cell lines was tested and, in a few of them, is identical to, or higher than, that of cisplatin. Series of diorganotin(IV) complexes of 4-X-benzohydroxamic acid [X = NH2 (HL1), NO2 (HL2) or F (HL3)] formulated as [R2SnL 2] and [R2Sn(L)]2O (R = Me, Et, nBu or Ph) have been prepared and characterized by FT-IR, 1H, 13C and 119Sn NMR spectroscopies, elemental analyses, FAB+-MS and melting point determination. They are stable in air, soluble in alcohols and in hydroalcoholic solution and, in some cases, in water. Their in vitro antitumor activity against a series of human tumor cell lines was tested and, in a few of them, is identical to, or even higher than, that of cisplatin. For the mononuclear dialkyltin compounds, the activity generally increases with the length of the carbon chain of the alkyl ligand, being higher for the complexes with benzohydroxamato ligands bearing an electron-acceptor substituent (X = NO2 or F). No structure-activity relationship based on the Hammett's σp constant, or related ones, has been recognized.

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