57084-39-6

Basic information

• Product Name: 1-methyl-1-(p-tolyl)siletane
• Synonyms: 1-methyl-1-(p-tolyl)siletane
• CAS NO: 57084-39-6
• Molecular Weight: 176.334
• Mol File: 57084-39-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-1-(p-tolyl)siletane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-1-(p-tolyl)siletane(57084-39-6)
• EPA Substance Registry System: 1-methyl-1-(p-tolyl)siletane(57084-39-6)

Safety Data

• Hazardous Substances Data: 57084-39-6(Hazardous Substances Data)

Upstream product

• 352-32-9 p-fluorotoluene 
• 2351-34-0 1-chloro-1-methylsiletane 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 106-38-7 para-bromotoluene 

Relevant articles and documents

Cobalt-Catalyzed Defluorosilylation of Aryl Fluorides via Grignard Reagent Formation

Transition-metal-catalyzed transformations of the carbon-fluorine bond not only tackle an interesting problem of challenging bond activation but also offer new synthetic strategies where the relatively inert C-F bond is converted to versatile functional groups. Herein we report a practical cobalt-catalyzed silylation of aryl fluorides that uses a cheap electrophilic silicon source with magnesium. This method is compatible with various silicon sources and can be operated under aerobic conditions. Mechanistic studies support the in situ formation of a Grignard reagent, which is captured by the electrophilic silicon source.