57159-81-6

Basic information

• Product Name: 1H-Benzimidazole,2-(methylsulfonyl)-(9CI)
• Synonyms: 2-(Methylsulfonyl)-1H-benzo[d]iMidazole;2-(Methylsulfonyl)benzimidazole;NSC 191930;2-(Methanesulfonyl)benzimidazole;1H-Benzimidazole,2-(methylsulfonyl)-(9CI);1H-BenziMidazole, 2-(Methylsulfonyl)-
• CAS NO: 57159-81-6
• Molecular Formula: C₈H₈N₂O₂S
• Molecular Weight: 196.22632
• Product Categories: BENZIMIDAZOLE
• Mol File: 57159-81-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 202 °C
• Boiling Point: 419.6°Cat760mmHg
• Flash Point: 207.6°C
• Appearance: /
• Density: 1.433g/cm³
• Vapor Pressure: 3E-07mmHg at 25°C
• Refractive Index: 1.642
• Storage Temp.: 2-8°C
• PKA: 9.12±0.10(Predicted)
• CAS DataBase Reference: 1H-Benzimidazole,2-(methylsulfonyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,2-(methylsulfonyl)-(9CI)(57159-81-6)
• EPA Substance Registry System: 1H-Benzimidazole,2-(methylsulfonyl)-(9CI)(57159-81-6)

Safety Data

• Hazardous Substances Data: 57159-81-6(Hazardous Substances Data)

Usage

General Description

1H-Benzimidazole, 2-(methylsulfonyl)-(9CI) is a chemical compound with the molecular formula C8H8N2O2S. It belongs to the class of benzimidazoles, which are heterocyclic compounds that contain a benzene ring fused to an imidazole ring. This particular compound contains a methylsulfonyl group, which is a sulfonyl group that is attached to a methyl group. The presence of the sulfonyl group gives this compound unique chemical properties, allowing it to be used in a variety of applications such as pharmaceuticals, agrochemicals, and materials science. Its specific uses may include being an intermediate in the synthesis of other organic compounds, or as a building block in the development of drugs and dyes. As with any chemical compound, it is important to handle 1H-Benzimidazole, 2-(methylsulfonyl)-(9CI) with caution and in accordance with safety guidelines.

InChI:InChI=1/C8H8N2O2S/c1-13(11,12)8-9-6-4-2-3-5-7(6)10-8/h2-5H,1H3,(H,9,10)

Upstream product

• 7152-24-1 2-methylsulfanylbenzimidazole 
• 98639-91-9 1-H-1,3-benzimidazol-2-yl methyl sulfoxide 
• 10213-10-2 sodium tungstate (VI) dihydrate 
• 583-39-1 2,3-dihydrobenzimidazol-2-thione 
• 134469-07-1 Benzimidazol-2-thiol 

Downstream Products

• 61078-14-6 1-methyl-2-(methylsulfonyl)-1H-benzo[d]imidazole 
• 100969-46-8 1-benzyl-2-methanesulfonyl-1H-benzimidazole 
• 946718-12-3 2-<(4-diphenylmethyl)-1-piperazinyl>-1H-benzimidazole 
• 4929-52-6 2-((4-methoxyphenyl)thio)-1H-benzo[d]imidazole 
• 1018987-23-9 C₁₃H₉ClN₂O 
• 1018987-22-8 C₁₉H₁₄N₂O 
• 1018987-20-6 C₁₃H₁₀N₂OS 
• 1018987-18-2 2-((3-fluorophenyl)thio)-1H-benzo[d]imidazole 
• 1018987-24-0 C₁₄H₉F₃N₂O 
• 1018987-29-5 C₁₃H₁₁N₃O 
• 446845-17-6 C₁₃H₁₁N₃O 
• 24752-30-5 N-(4-chlorophenyl)-1H-benzo[d]imidazol-2-amine 
• 2360-29-4 2-(phenylsulfanyl)-1H-benzimidazole 
• 1018987-21-7 C₁₄H₁₂N₂O 

Relevant articles and documents

Metal-Free Aminomethylation of Aromatic Sulfones Promoted by Eosin Y

A metal-free α-aminomethylation of heteroaryls promoted by eosin Y under green light irradiation is reported. A large variety of α-trimethylsilylamines as precursor of α-aminomethyl radical species were engaged to functionalize sulfonyl-heteroaryls following a Homolytic Aromatic Substitution (HAS) pathway. This method has provided a range of α-aminoheteroaryl compounds including a functionalized natural product. The mechanism of this late-stage functionalization of aryls was investigated and suggests the formation of a sulfonyl radical intermediate over a reductive quenching cycle.

Polyoxomolybdate-Calix[4]arene Hybrid: A Catalyst for Sulfoxidation Reactions with Hydrogen Peroxide

An easily accessible polyoxomolybdate-calix[4]arene hybrid 1 has been synthesized and applied as a heterogeneous catalyst in the sulfoxidation of thioethers to sulfoxides and to sulfones under strictly stoichiometric amounts of 30% H2O2 in CH3CN as the solvent. This study represents the first promising example of successful employment of calixarenes-polyoxometalate (POM) hybrid materials in the area of catalytic oxidations.

TiCl4 hiocarbonyls and oxidation of sulfides in the presence of H2O2

H2O2 in combination with TiCl4 proved to be a highly reactive reagent system for the desulfurization of thioamide and thioketone derivatives in excellent yields and short reaction times with high purity. Sulfides were also found to undergo oxidation to sulfones under similar reaction conditions. In most cases, these reactions are highly selective, simple, and clean, affording products in high yields and purity.