57229-36-4

Basic information

• Product Name: 5,6-diMethylpyrazin-2-ol
• Synonyms: 5,6-diMethylpyrazin-2-ol;5,6-diMethyl-2-hydroxypyrazine;5,6-dimethyl-2(1H)-Pyrazinone;2,3-Dimethyl-5-hydroxypyrazine;5,6-Dimethylpyrazin-2(1H)-one
• CAS NO: 57229-36-4
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14052
• EINECS: -0
• Mol File: 57229-36-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 200-201 °C
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 11.78±0.60(Predicted)
• CAS DataBase Reference: 5,6-diMethylpyrazin-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-diMethylpyrazin-2-ol(57229-36-4)
• EPA Substance Registry System: 5,6-diMethylpyrazin-2-ol(57229-36-4)

Safety Data

• Hazardous Substances Data: 57229-36-4(Hazardous Substances Data)

Upstream product

• 431-03-8 dimethylglyoxal 
• 598-41-4 H-Gly-NH₂ 
• 59489-32-6 2-chloro-5,6-dimethylpyrazine 
• 65464-21-3 2,3-dimethyl-1,4-diazine N-oxide 
• 1252906-06-1 2,3-dimethyl-5-[(phenylmethyl)oxy]pyrazine 
• 1668-10-6 glycinamide hydrochloride 
• 855235-97-1 bromo-acetic acid-(1-methyl-2-oxo-propylamide) 
• 7664-41-7 ammonia 
• 5910-89-4 2,3-dimethylpyrazine 
• 145458-83-9 1-benzyloxy-5,6-dimethyl-2(1H)-pyrazinone 

Downstream Products

• 100142-33-4 5,6-dimethyl-3-phenyl-1H-pyrazin-2-one 
• 100517-68-8 5,6-dimethyl-3-phenylazo-1H-pyrazin-2-one 
• 59489-32-6 2-chloro-5,6-dimethylpyrazine 
• 111454-68-3 5-bromo-2,3-dimethylpyrazine 
• 100450-13-3 3-bromo-5,6-dimethyl-1H-pyrazin-2-one 
• 140862-47-1 2,3-Dimethyl-6-phenyl-furo[2,3-b]pyrazine 
• 32493-62-2 5,6-dimethyl-1,4-dihydro-pyrazine-2,3-dione 
• 32493-79-1 5,6-Dichloro-2,3-dimethylpyrazine 
• 1391986-79-0 2,3-dimethyl-5-phenylpyrazine 
• 1391986-80-3 5-(4-methoxyphenyl)-2,3-dimethylpyrazine 
• 1391986-81-4 5-(3-fluorophenyl)-2,3-dimethylpyrazine 
• 1391986-82-5 5-(4-tert-butylphenyl)-2,3-dimethylpyrazine 
• 15834-78-3 2-n-Butyl-5,6-dimethyl-pyrazin 
• 32263-00-6 2,3-dimethyl-5-(1-methylpropyl)-pyrazine 

Relevant articles and documents

Regioselective synthesis of trialkylpyrazines via nickel-catalyzed Negishi cross-coupling of pyrazine triflate

A regioselective synthesis of trialkylpyrazines via nickel-catalyzed cross-coupling reaction of pyrazine triflate is reported. The 5-substituted 2,3-dimethylpyrazine derivatives including trail pheromone components of the ant Eutetramorium mocquerysi have been successfully synthesized in good yields by nickel-catalyzed Negishi cross-coupling reactions of pyrazine triflate mediated by alkyl and arylzinc halides. Georg Thieme Verlag Stuttgart · New York.

At-hydroxyamide-containing heterocycles. Part 7. Preparation and photochemical behavior of 1-benzyloxy-2(1H)-pyrazinones

Synthesis of 1-benzyloxy-2(1H)-pyrazinones having substituents at C-5 and C-6 positions and their photochemical behavior have been studied. Upon irradiation 1-benzyloxy-2(1H)-pyrazmones underwent N-O bond cleavage in high quantum yields. The rearrangement of the benzyioxy group to C-3 position of the ring and [2+2] cycloaddition were also observed.