57230-08-7

Basic information

• Product Name: 2-amino-1-cyclohexylethanol
• Synonyms: 2-amino-1-cyclohexylethanol;2-Amino-1-cyclohexylethan-1-ol
• CAS NO: 57230-08-7
• Molecular Formula: C₈H₁₇NO
• Molecular Weight: 143.23
• Mol File: 57230-08-7.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-1-cyclohexylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-1-cyclohexylethanol(57230-08-7)
• EPA Substance Registry System: 2-amino-1-cyclohexylethanol(57230-08-7)

Safety Data

• Hazardous Substances Data: 57230-08-7(Hazardous Substances Data)

Usage

General Description

2-Amino-1-cyclohexylethanol, also known as p-adamantyl-phenethylamine, is a chemical compound that contains an amine and an alcohol functional group. It is used in various industrial applications, including as a corrosion inhibitor, stabilizer for emulsions, and as a component in adhesives and sealants. It is also used in the synthesis of pharmaceutical compounds. 2-Amino-1-cyclohexylethanol has been found to have potential antimicrobial and antifungal properties, and it is being studied for its potential use in medical and biotechnological applications. Additionally, it has been identified as a potential precursor for the synthesis of novel organic compounds with potential pharmaceutical or industrial applications. Overall, 2-amino-1-cyclohexylethanol has a range of potential uses and applications in various industries.

Upstream product

• 36929-66-5 1-oxaspiro<2,5>octane-2-carboxylic acid nitrile 
• 100-50-5 3-Cyclohexene-1-carboxaldehyde 
• 4410-31-5 (RS)-mandelamide 
• 2043-61-0 cyclohexanecarbaldehyde 
• 141377-56-2 1-cyclohexyl-2-nitroethanol 
• 40748-85-4 2-Nitro-1-hydroxy-1--aethan 
• 100007-62-3 2-cyclohexyl-2-hydroxyacetonitrile 
• 4442-93-7 2-cyclohexyl-2-hydroxyethanamide 

Downstream Products

• 1000374-94-6 5-Cyclohexyl-oxazolidin-2-one 
• 185426-16-8 (2R)-(-)-1-tert-butoxycarbonylamino-2-cyclohexylethan-2-ol 
• 1426152-50-2 C₁₅H₂₀N₄O₂S 
• 1414772-44-3 2-{[3-(1-benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl]amino}-1-cyclohexylethanol 
• 1224735-53-8 (S)-4-(3-(tert-butyldimethylsilyloxy)phenyl)-N-(2-cyclohexyl-2-hydroxyethyl)-6-ethyl-2-oxo-1,2,3,4-tetrahydropyrimidin-5-carboxamide 
• 913642-39-4 1,1-dimethylethyl (2-cyclohexyl-2-hydroxyethyl)carbamate 
• 24446-49-9 <2-Acetylamino-1-hydroxy-aethyl-(1)>-cyclohexan 

Relevant articles and documents

Liquid chromatography enantiomeric separation of chiral ethanolamine substituted compounds

Eleven racemic ethanolamine derivatives were prepared, and their enantiomers were separated using liquid chromatography with various chiral columns. These derivatives included chiral vicinal amino alcohols, β-hydroxy ureas, β-hydroxy thioureas, and β-hydr

Chiral-Organotin-Catalyzed Kinetic Resolution of Vicinal Amino Alcohols

A highly efficient kinetic resolution of racemic amino alcohols has been achieved for the first time with a chiral tin catalyst. A chiral organotin compound with 3,4,5-trifluorophenyl groups at the 3,3′-positions of the binaphthyl framework enabled this transformation with excellent yield and high enantioselectivity. The process tolerates aryl- and alkyl-substituted amino alcohols and a variety of other substrates, affording the corresponding products in high enantioselectivity and with s factors up to >500.

Kinetic resolution of racemic amino alcohols through intermolecular acetalization catalyzed by a chiral Bronsted acid

The kinetic resolution of racemic secondary alcohols is a fundamental method for obtaining enantiomerically enriched alcohols. Compared to esterification, which is a well-established method for this purpose, kinetic resolution through enantioselective intermolecular acetalization has not been reported to date despite the fact that the formation of acetals is widely adopted to protect hydroxy groups. By taking advantage of the thermodynamics of acetalization by the addition of alcohols to enol ethers, a highly efficient kinetic resolution of racemic amino alcohols was achieved for the first time and in a practical manner using a chiral phosphoric acid catalyst.