57355-08-5

Basic information

• Product Name: 3,5,6-triMethylpyrazin-2-ol
• Synonyms: 3,5,6-triMethylpyrazin-2-ol;3,5,6-TriMethylpyrazin-2(1H)-one;3,5,6-trimethyl-2(1H)-Pyrazinone;3,5,6-Trimethyl-1H-pyrazin-2-one
• CAS NO: 57355-08-5
• Molecular Formula: C7H10N2O
• Molecular Weight: 138.1671
• Mol File: 57355-08-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5,6-triMethylpyrazin-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5,6-triMethylpyrazin-2-ol(57355-08-5)
• EPA Substance Registry System: 3,5,6-triMethylpyrazin-2-ol(57355-08-5)

Safety Data

• Hazardous Substances Data: 57355-08-5(Hazardous Substances Data)

Usage

General Description

3,5,6-trimethylpyrazin-2-ol is a chemical compound with a molecular formula C7H10N2O. It is a derivative of pyrazine and contains three methyl groups, which are responsible for its distinctive odor. 3,5,6-triMethylpyrazin-2-ol is commonly used as a flavoring agent in the food industry due to its nutty and roasted taste. It is also used in the production of fragrances and perfumes. Additionally, 3,5,6-trimethylpyrazin-2-ol has been studied for its potential medicinal properties, including its potential as an anti-inflammatory and antioxidant agent. Its unique chemical structure and properties make it a valuable ingredient in various industries and a subject of interest for further research.

Upstream product

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Downstream Products

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• 38052-24-3 1,3,5,6-tetramethylpyrazin-2-one 

Relevant articles and documents

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Studies on the mechanism of 1,2-dihydropyrazin-2-one ring formation from dipeptidyl chloromethyl ketone and its chemical properties: Immediate deamination during catalytic hydrogenation

1,2-Dihydropyrazin-2-one derivatives, which have two aminoalkyl groups at the positions 3 and 6, were found to be efficient tools for the construction of potent, selective and long-acting opioid mimetics. During the course of preparation, we found that the catalytic hydrogenation of 3,6- bis(benzyloxycarbonylaminomethyl)-5-methyl-1,2-dihydropyrazin-2-one to remove the benzyloxycarbonyl groups resulted in a side reaction. By MS and NMR studies and by preparation of additional 1,2-dihydropyrazin-2-one derivatives, the structure of the by-product was identified as 3-aminomethyl-5,6-dimethyl-1,2- dihydropyrazin-2-one. Preparation of additional compounds substituted with deuterium provided us with sufficient information to confirm the structure of the product and to support a cyclization mechanism in its formation.

PYRAZINES, PYRIMIDINES AND PYRIDAZINES USEFUL IN THE TREATMENT OF SENILE DEMENTIA

The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic ring system; and independently substituted on each of the other ring carbon atoms with a substituent of low lipophilicity or a hydrocarbon substituent; which compounds stimulate central muscarinic acetylcholine receptors and therefore are useful in the treatment of neurological and mental illnesses.