Welcome to LookChem.com Sign In|Join Free

CAS

  • or

576-83-0

Post Buying Request

576-83-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

576-83-0 Usage

Chemical Properties

colorless liquid

Uses

2-Bromomesitylene is a useful synthetic intermediate, Aromatics, Boron Derivatives, Catalyst. It is an intermediate used to prepare Hydrogen[4-[bis(2,4,6-trimethylphenyl)phosphino]-2,3,5,6-tetrafluorophenyl]hydrobis(2,3,4,5,6-pentafluorophenyl)borate (H714510) which is a frustrated phosphonium borate for metal-free catalytic hydrogenation of imines.

Check Digit Verification of cas no

The CAS Registry Mumber 576-83-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 576-83:
(5*5)+(4*7)+(3*6)+(2*8)+(1*3)=90
90 % 10 = 0
So 576-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H11Br/c1-6-4-7(2)9(10)8(3)5-6/h4-5H,1-3H3

576-83-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A12277)  2-Bromomesitylene, 99%   

  • 576-83-0

  • 50g

  • 311.0CNY

  • Detail
  • Alfa Aesar

  • (A12277)  2-Bromomesitylene, 99%   

  • 576-83-0

  • 100g

  • 595.0CNY

  • Detail
  • Alfa Aesar

  • (A12277)  2-Bromomesitylene, 99%   

  • 576-83-0

  • 250g

  • 1403.0CNY

  • Detail
  • Alfa Aesar

  • (A12277)  2-Bromomesitylene, 99%   

  • 576-83-0

  • 500g

  • 2680.0CNY

  • Detail

576-83-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4,6-Trimethybromombenzene

1.2 Other means of identification

Product number -
Other names Benzene, 2-bromo-1,3,5-trimethyl-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:576-83-0 SDS

576-83-0Synthetic route

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With N-Bromosuccinimide; perchloric acid In tetrachloromethane for 22h; Ambient temperature;99%
With hydrogen bromide; dihydrogen peroxide In water at 20℃; for 24h; Darkness;98%
With gold(III) chloride; N-Bromosuccinimide In dichloromethane at 20℃; for 12h; Inert atmosphere;98%
mesitylenecarboxylic acid
480-63-7

mesitylenecarboxylic acid

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With potassium phosphate; tetrabuthylammonium tribromide In acetonitrile at 100℃; for 16h;94%
2,4,6-trimethylaniline
88-05-1

2,4,6-trimethylaniline

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With N-Bromosuccinimide; sodium nitrite In N,N-dimethyl-formamide at 20℃; for 6h;88%
With tert.-butylnitrite; copper(ll) bromide In acetonitrile
triethyl(mesityl)germane

triethyl(mesityl)germane

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 4h;80%
1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

2,4-dibromomesitylene
6942-99-0

2,4-dibromomesitylene

Conditions
ConditionsYield
With bromine In tetrachloromethane Product distribution / selectivity;A 73%
B n/a
With bromine; silica gel In tetrachloromethane at 20℃;A 13%
B 70 % Chromat.
With N-Bromosuccinimide; toluene-4-sulfonic acid In dichloromethane Product distribution; Ambient temperature; var. catalyst, var solvent, var. aromatic;
1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

2-bromomesitylene
1667-04-5

2-bromomesitylene

Conditions
ConditionsYield
With chloroamine-T; iron(II) bromide In dichloromethane for 189.6h; Ambient temperature;A 51%
B 0.3%
With bromine at 100℃; for 4h; Reflux; Ionic liquid;
1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

A

1-bromomethyl-3,5-dimethylbenzene
27129-86-8

1-bromomethyl-3,5-dimethylbenzene

B

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With sodium bromate; sodium hydrogensulfite In cyclohexane; water at 50℃; for 4h; Bromination;A 50%
B 11%
With bromine at 120℃; for 6h; UV-irradiation; Title compound not separated from byproducts;
With N-Bromosuccinimide at 150℃; under 2625.26 Torr; for 0.0666667h; microwave irradiation;A 42 % Chromat.
B 6 % Chromat.
isopropyl mesityl sulfone
22739-91-9

isopropyl mesityl sulfone

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

2,4,6-trimethylbenzenesulfonyl bromide
60057-49-0

2,4,6-trimethylbenzenesulfonyl bromide

C

α-bromoisopropyl mesityl sulfone

α-bromoisopropyl mesityl sulfone

D

2,3-dimethyl-3-mesitylenesulfonyl-2-butanol

2,3-dimethyl-3-mesitylenesulfonyl-2-butanol

Conditions
ConditionsYield
Stage #1: isopropyl mesityl sulfone With n-butyllithium In tetrahydrofuran; hexane at -63℃; for 1h;
Stage #2: With bromine In tetrahydrofuran; hexane at -55℃; for 1.5h; Further stages.;
A 6%
B 5%
C 48%
D 37%
(2,4,6-trimethylphenyl)diazonium tetrafluoronorate

(2,4,6-trimethylphenyl)diazonium tetrafluoronorate

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

2-bromomesitylene
1667-04-5

2-bromomesitylene

Conditions
ConditionsYield
With sodium bromide; sodium chloride In water; glycerol at 21 - 23.5℃; Product distribution; Kinetics; investigations of thermal dediazoniation in various solvents as a function of viscosity; the reaction are diffusion controlled;A 14.5%
B 6%
mesitylene sulfonic acid
3453-83-6

mesitylene sulfonic acid

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With copper(ll) bromide
bis(2,4,6-trimethylphenyl)disulfide
1483-92-7

bis(2,4,6-trimethylphenyl)disulfide

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With bromine In dichloromethane at -30℃; for 0.166667h;
bromine
7726-95-6

bromine

nitric acid
7697-37-2

nitric acid

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
je nach dem Mengenverhaeltnis der Verbindungen;
aluminium bromide
7727-15-3

aluminium bromide

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

diselenium dibromide

diselenium dibromide

carbon disulfide solution

carbon disulfide solution

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

dimesityl

dimesityl

Ni(mes)(Ph)(PMe2Ph)2

Ni(mes)(Ph)(PMe2Ph)2

A

bromobenzene
108-86-1

bromobenzene

B

1-phenyl-2,4,6-trimethylbenzene
3976-35-0

1-phenyl-2,4,6-trimethylbenzene

C

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

D

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

Conditions
ConditionsYield
With bromine In diethyl ether for 0.5h; Ambient temperature; Yield given;
Ni(mes)(o-tol)(PEt3)2

Ni(mes)(o-tol)(PEt3)2

A

2-methylphenyl bromide
95-46-5

2-methylphenyl bromide

B

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

C

2,2',4,6-tetramethylbiphenyl
89970-02-5

2,2',4,6-tetramethylbiphenyl

D

3-bromo-2,2',4,6-tetramethyl-1,1'-biphenyl

3-bromo-2,2',4,6-tetramethyl-1,1'-biphenyl

Conditions
ConditionsYield
With bromine In diethyl ether for 0.5h; Ambient temperature; Yield given;
Ni(mes)(o-tol)(PMe2Ph)2

Ni(mes)(o-tol)(PMe2Ph)2

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

2,4-dibromotoluene
31543-75-6

2,4-dibromotoluene

C

2,2',4,6-tetramethylbiphenyl
89970-02-5

2,2',4,6-tetramethylbiphenyl

D

3-bromo-2,2',4,6-tetramethyl-1,1'-biphenyl

3-bromo-2,2',4,6-tetramethyl-1,1'-biphenyl

Conditions
ConditionsYield
With bromine In diethyl ether for 0.5h; Ambient temperature; Yield given. Further byproducts given;
Ni(o-ClPh)(mes)(PMe2Ph)2

Ni(o-ClPh)(mes)(PMe2Ph)2

A

2-bromo-1-chlorobenzene
694-80-4

2-bromo-1-chlorobenzene

B

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

C

chlorobenzene
108-90-7

chlorobenzene

D

3-Bromo-2'-chloro-2,4,6-trimethyl-biphenyl

3-Bromo-2'-chloro-2,4,6-trimethyl-biphenyl

Conditions
ConditionsYield
With bromine In diethyl ether for 0.5h; Ambient temperature; Yield given;
Di-tert-butylmesitylsilan

Di-tert-butylmesitylsilan

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

Di-tert-butyl-bromsilan
59409-85-7

Di-tert-butyl-bromsilan

Conditions
ConditionsYield
With bromine In pentane at -5 - 20℃; Title compound not separated from byproducts;
(2,4,6-trimethylphenyl)diazonium tetrafluoronorate

(2,4,6-trimethylphenyl)diazonium tetrafluoronorate

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

1-fluoro-2,4,6-trimethylbenzene
392-69-8

1-fluoro-2,4,6-trimethylbenzene

Conditions
ConditionsYield
With trimethylsilyl bromide; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 55℃; for 2h;A 87 % Chromat.
B 13 % Chromat.
With trimethylsilyl bromide; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; copper(I) bromide at 70℃; Schiemann reaction;A 4 % Chromat.
B 96 % Chromat.
2,4,6-trimethyl 1-deuterio benzene
37055-29-1

2,4,6-trimethyl 1-deuterio benzene

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

C9H10(2)HBr
1332484-20-4

C9H10(2)HBr

Conditions
ConditionsYield
With gold(III) chloride; N-Bromosuccinimide In 1,2-dichloro-ethane at 20℃; for 6h; Kinetics;
1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

2,4,6-tribromomesitylene
608-72-0

2,4,6-tribromomesitylene

C

2,4-dibromomesitylene
6942-99-0

2,4-dibromomesitylene

Conditions
ConditionsYield
With Oxone; quartz; sodium bromide In n-heptane for 0.333333h; Milling;
2-mesitylmagnesium bromide
2633-66-1

2-mesitylmagnesium bromide

A

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

B

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

Conditions
ConditionsYield
With C44H45Br3N4Ni In benzene-d6 Inert atmosphere;A 50 %Spectr.
B 33 %Spectr.
mesityldiazonium tetrakis(pentafluorophenyl)borate

mesityldiazonium tetrakis(pentafluorophenyl)borate

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 16 h / 30 °C / Sealed tube
2: sodium bromide / [(2)H6]acetone; water / 0.17 h / 20 °C
View Scheme
(2,4,6-trimethylphenyl)diazonium tetrafluoronorate

(2,4,6-trimethylphenyl)diazonium tetrafluoronorate

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dichloromethane; toluene / 1 h / 0 °C
2: 16 h / 30 °C / Sealed tube
3: sodium bromide / [(2)H6]acetone; water / 0.17 h / 20 °C
View Scheme
(E)-(2-chlorovinyl)(mesityl)[tetrakis(pentafluorophenyl)borato]-λ3-chlorane

(E)-(2-chlorovinyl)(mesityl)[tetrakis(pentafluorophenyl)borato]-λ3-chlorane

A

Z-1-bromo-2-chloroethylene
72256-09-8

Z-1-bromo-2-chloroethylene

B

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

Conditions
ConditionsYield
With sodium bromide In [(2)H6]acetone; water at 20℃; for 0.166667h; stereoselective reaction;A n/a
B n/a
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

1,5-diamino-3-azapentane
111-40-0

1,5-diamino-3-azapentane

(2,4,6-Me3C6H2NHCH2CH2)2NH
236111-35-6

(2,4,6-Me3C6H2NHCH2CH2)2NH

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium (0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene Heating;100%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

thiophen-2-yl magnesium bromide
5713-61-1

thiophen-2-yl magnesium bromide

2-(2,4,6-trimethylphenyl)thiophene
920449-57-6

2-(2,4,6-trimethylphenyl)thiophene

Conditions
ConditionsYield
Stage #1: thiophen-2-yl magnesium bromide With dichloro(1,3-bis(2,6-bis(3-pentyl)phenyl)imidazolin-2-ylidene)(3-chloropyridyl)palladium(II); zinc(II) chloride In tetrahydrofuran at 23℃; for 0.333333h; Inert atmosphere;
Stage #2: 2,4,6-trimethylphenyl bromide In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 23℃; for 24h; Negishi coupling; Inert atmosphere;
100%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline
214360-73-3

4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline

2′,4′,6′-trimethylbiphenyl-4-amine
66818-61-9

2′,4′,6′-trimethylbiphenyl-4-amine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane for 17h; Suzuki-Miyaura Coupling; Inert atmosphere; Reflux;100%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2,2'-(5,10-dimesitylindeno[2,1-a]indene-2,7-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

2,2'-(5,10-dimesitylindeno[2,1-a]indene-2,7-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

2,5,7,10-tetramesitylindeno[2,1-a]indene

2,5,7,10-tetramesitylindeno[2,1-a]indene

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In water; toluene at 95℃; for 20h; Suzuki-Miyaura Coupling; Inert atmosphere;100%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2,4,6-trimethylaniline
88-05-1

2,4,6-trimethylaniline

Conditions
ConditionsYield
With 2-((dicyclohexylphosphino)methyl)-1,3-bis(2,6-diisopropylphenyl)-4,5-dimethyl-1H-imidazol-3-ium iodide; ammonia; palladium diacetate; sodium t-butanolate In 1,4-dioxane at 120℃; under 7500.75 Torr; for 24h; Autoclave; Inert atmosphere;99%
With copper(l) iodide; sodium azide; N,N`-dimethylethylenediamine In dimethyl sulfoxide at 100℃; for 10h; Inert atmosphere;72%
Stage #1: 2,4,6-trimethylphenyl bromide With magnesium In tetrahydrofuran Inert atmosphere;
Stage #2: With 3-tert-butyl-3-phenyloxaziridine In tetrahydrofuran; toluene at -45℃; for 2h; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; water; toluene Reagent/catalyst; Inert atmosphere;
31%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

phenylboronic acid
98-80-6

phenylboronic acid

1-phenyl-2,4,6-trimethylbenzene
3976-35-0

1-phenyl-2,4,6-trimethylbenzene

Conditions
ConditionsYield
With caesium carbonate; palladium diacetate; P(i-BuNCH2CH2)3N In toluene at 80℃; Suzuki cross-coupling reaction;99%
With [(trineopentylphosphine)PdCl2]2; sodium carbonate In water; toluene at 23℃; for 17h; Catalytic behavior; Temperature; Reagent/catalyst; Solvent; Suzuki-Miyaura Coupling; Sealed tube; Inert atmosphere;99%
With palladium diacetate; N,N'-dicyclohexylethylenediimine; caesium carbonate In 1,4-dioxane at 80℃; for 4h; Suzuki-Miyaura cross-coupling reaction;97%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2-methoxy-phenylamine
90-04-0

2-methoxy-phenylamine

N-(2-methoxyphenyl)-N-(2,4,6-trimethylphenyl)amine
39267-49-7

N-(2-methoxyphenyl)-N-(2,4,6-trimethylphenyl)amine

Conditions
ConditionsYield
With palladium diacetate; P(i-BuNCH2CH2)3N; sodium t-butanolate In toluene at 80℃;99%
With palladium diacetate; 9,9-dimethyl-4,6-bis(diphenylphosphino)xanthene; sodium t-butanolate In toluene at 80℃; for 68h;97%
With palladium diacetate; sodium t-butanolate; tri tert-butylphosphoniumtetrafluoroborate In toluene at 120℃; for 24h; Glovebox; Inert atmosphere;79%
With 5,5-dimethyl-1,9-(PPh2)2-xanthene; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate In toluene at 100℃;
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

2,2',4,6-tetramethylbiphenyl
89970-02-5

2,2',4,6-tetramethylbiphenyl

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0) In tetrahydrofuran; toluene at 60℃; for 16h; Inert atmosphere;99%
With potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine In tetrahydrofuran at 20℃; for 18h; Reagent/catalyst; Concentration; Temperature; Suzuki-Miyaura Coupling; Inert atmosphere; Glovebox;98%
With sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐3‐sulfonate; palladium diacetate; potassium carbonate In water at 20℃; for 22h; Suzuki-Miyaura coupling;94%
Benzophenone imine
1013-88-3

Benzophenone imine

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

N-(diphenyl methylene)-2,4,6-trimethylaniline
67565-93-9

N-(diphenyl methylene)-2,4,6-trimethylaniline

Conditions
ConditionsYield
With potassium tert-butylate; bis(dibenzylideneacetone)-palladium(0); 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride In 1,4-dioxane at 80℃; for 10h;99%
morpholine
110-91-8

morpholine

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

N-(2,4,6-trimethylphenyl)morpholine

N-(2,4,6-trimethylphenyl)morpholine

Conditions
ConditionsYield
With (1,3-bis(2,6-diisopropylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene)Pd(cinnamyl, 3-phenylallyl)Cl; sodium t-butanolate In neat (no solvent) at 110℃; for 12h; Buchwald-Hartwig Coupling; Inert atmosphere; Green chemistry;99%
With [Pd(N,N'-bis(2,6-bis(di-p-tolylmethyl)-4-methylphenyl)-imidazol-2-ylidene)(acetylacetonate)Cl]; lithium hexamethyldisilazane In 1,4-dioxane at 110℃; for 3h; Buchwald-Hartwig Coupling; Inert atmosphere; Sealed tube;95%
With (SIPr)Pd(cinnanmyl)Cl; potassium tert-butylate In 1,2-dimethoxyethane at 20℃; for 0.5h; Buchwald-Hartwig reaction;94%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

aniline
62-53-3

aniline

N-mesitylaniline
23592-67-8

N-mesitylaniline

Conditions
ConditionsYield
With (1,3-bis(2,6-diisopropylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene)Pd(cinnamyl, 3-phenylallyl)Cl; sodium t-butanolate In neat (no solvent) at 110℃; for 12h; Buchwald-Hartwig Coupling; Inert atmosphere; Green chemistry;99%
With (2-mesityl-1H-inden-3-yl)dicyclohexyl phosphine; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate In 1,2-dimethoxyethane at 120℃; for 24h; Buchwald-Hartwig amination; Inert atmosphere;98%
With air; potassium 2-methylbutan-2-olate; [(1,3-(2,6-iPr2C6H3)2-1,3-dihydroimidazol-2-ylidene)PdCl2]2 In 1,2-dimethoxyethane for 4h; Heating;92%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

1,3,5-trimethyl-benzene
108-67-8

1,3,5-trimethyl-benzene

Conditions
ConditionsYield
With potassium fluoride In tetrahydrofuran; water at 80℃; for 8h; Time; Schlenk technique; Sealed tube; Inert atmosphere;99%
With [2-(di-tert-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine]ruthenium(II) chlorocarbonyl hydride; isopropyl alcohol; sodium t-butanolate at 100℃; for 48h; Inert atmosphere; Sealed tube; Green chemistry;89%
With isopropyl alcohol at 20℃; for 24h; UV-irradiation; chemoselective reaction;88%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2,6-dimethylaniline
87-62-7

2,6-dimethylaniline

N-(2,4,6-trimethylphenyl)-N-(2,6-dimethylphenyl)amine
68014-58-4

N-(2,4,6-trimethylphenyl)-N-(2,6-dimethylphenyl)amine

Conditions
ConditionsYield
With palladium diacetate; P(i-BuNCH2CH2)3N; sodium t-butanolate In toluene at 80℃;99%
With sodium t-butanolate; palladium diacetate In toluene at 80℃; for 4h; Buchwald-Hartwig amination;98%
With tris-(dibenzylideneacetone)dipalladium(0); rac-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; sodium t-butanolate In toluene at 110℃; for 20h; Inert atmosphere;98%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

1-Naphthylboronic acid
13922-41-3

1-Naphthylboronic acid

1-(2,4,6-trimethylphenyl)naphthalene
22187-05-9

1-(2,4,6-trimethylphenyl)naphthalene

Conditions
ConditionsYield
With potassium phosphate; C29H37O2P; palladium diacetate In toluene at 110℃; for 3h; Reagent/catalyst; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;99%
With C36H43Br2ClN2Pd; potassium tert-butylate In isopropyl alcohol at 20℃; for 2h; Reagent/catalyst; Suzuki Coupling; Inert atmosphere; Schlenk technique; Glovebox;97%
With (IPr)Pd(cinnanmyl)Cl; potassium tert-butylate In isopropyl alcohol at 20℃; for 3.5h; Suzuki-Miyaura coupling;89%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

phenylacetylene
536-74-3

phenylacetylene

1-(phenylethynyl)-2,4,6-trimethylbenzene
29778-31-2

1-(phenylethynyl)-2,4,6-trimethylbenzene

Conditions
ConditionsYield
With pyrrolidine; triphenylphosphine; 1-butyl-3-methylimidazolium Tetrafluoroborate; bis(η3-allyl-μ-chloropalladium(II)) at 130℃; for 48h; Heck alkynylation;99%
With caesium carbonate; Pd[1,3,5,7-Me4-2,4,8-trioxa-6-Ph-6-phosphaadamantane]2*dba In acetonitrile at 60℃; for 12h; Sonogashira reaction;93%
With dichloro[1-(3,5-dimethylbenzyl)-3-(4-adamantylbenzyl)-5,6-dimethylbenzimidazole-2-ylidene]triphenylphosphine palladium(II); potassium tert-butylate In N,N-dimethyl-formamide at 100℃; for 3h; Reagent/catalyst; Sonogashira Cross-Coupling; Schlenk technique;90%
4-Methoxybenzophenone
611-94-9

4-Methoxybenzophenone

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

(4-methoxyphenyl)phenyl(2,4,6-trimethylphenyl)methanol

(4-methoxyphenyl)phenyl(2,4,6-trimethylphenyl)methanol

Conditions
ConditionsYield
Stage #1: 2,4,6-trimethylphenyl bromide With magnesium In tetrahydrofuran
Stage #2: 4-Methoxybenzophenone In tetrahydrofuran for 18h; Heating;
99%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

trans-2-phenylvinylboronic acid
6783-05-7

trans-2-phenylvinylboronic acid

(E)-2,4,6-trimethylstilbene
17024-58-7

(E)-2,4,6-trimethylstilbene

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate In tetrahydrofuran at 40℃; for 24h; Suzuki-Miyaura coupling;99%
With potassium tert-butylate; ClPd[N,N(2,6-iPr2C6H3)2-imidazol-2-yl]cinnamyl In isopropyl alcohol at 20℃; for 1.5h; Suzuki-Miyaura cross-coupling reaction;92%
tetramethyldivinyldisiloxane
2627-95-4

tetramethyldivinyldisiloxane

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2,4,6-trimethylstyrene
769-25-5

2,4,6-trimethylstyrene

Conditions
ConditionsYield
With johnphos; bis(η3-allyl-μ-chloropalladium(II)) In N,N-dimethyl-formamide at 40℃; for 24h;99%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2-chloro-5-methoxyaniline
2401-24-3

2-chloro-5-methoxyaniline

2-chloro-5-methoxy-N-(2,4,6-trimethylphenyl)aniline
1188930-01-9

2-chloro-5-methoxy-N-(2,4,6-trimethylphenyl)aniline

Conditions
ConditionsYield
With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene for 18h; Inert atmosphere; Reflux;99%
1,5-diaminopentane
462-94-2

1,5-diaminopentane

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

N1,N5-dimesitylpentane-1,5-diamine
1226754-96-6

N1,N5-dimesitylpentane-1,5-diamine

Conditions
ConditionsYield
With sodium t-butanolate; (R)-(-)-1-[(SP)-2-(dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine; palladium diacetate In 1,2-dimethoxyethane at 100℃; for 6h;99%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

cyanomesitylene
2571-52-0

cyanomesitylene

Conditions
ConditionsYield
Stage #1: 2,4,6-trimethylphenyl bromide With n-butyllithium In tetrahydrofuran; hexane at -70 - 0℃;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; hexane at 0℃; for 1h;
Stage #3: With ammonia; iodine In tetrahydrofuran; hexane; water at 0 - 20℃;
99%
Stage #1: 2,4,6-trimethylphenyl bromide With n-butyllithium In tetrahydrofuran; hexane at -70 - 0℃; for 0.583333h;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; hexane at 0℃; for 1h;
Stage #3: With ammonia; iodine In tetrahydrofuran; hexane; water at 0 - 20℃; for 2h;
99%
Stage #1: 2,4,6-trimethylphenyl bromide; N,N-dimethyl-formamide With magnesium In tetrahydrofuran at 20℃;
Stage #2: With ammonia; iodine In tetrahydrofuran; water at 20℃;
79%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

(1-methyl-1H-pyrazol-4-yl)boronic acid
847818-55-7

(1-methyl-1H-pyrazol-4-yl)boronic acid

4-mesityl-1-methyl-1H-pyrazole
1246888-97-0

4-mesityl-1-methyl-1H-pyrazole

Conditions
ConditionsYield
With potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); rac-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole In water; butan-1-ol at 100℃; for 24h; Suzuki coupling; Inert atmosphere;99%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

C14H20BO3(1-)*K(1+)

C14H20BO3(1-)*K(1+)

bimesityl
4482-03-5

bimesityl

Conditions
ConditionsYield
With palladium diacetate; 2,2'-bis(diphenylphosphino)biphenyl; copper(l) chloride In N,N-dimethyl-formamide at 80℃; for 14h; Inert atmosphere;99%
lithium trimethoxy(1,2,2-trifluorovinyl)borate

lithium trimethoxy(1,2,2-trifluorovinyl)borate

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

1,3,5-trimethyl-2-(1,2,2-trifluorovinyl)benzene
2972-89-6

1,3,5-trimethyl-2-(1,2,2-trifluorovinyl)benzene

Conditions
ConditionsYield
With potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); XPhos In tetrahydrofuran at 20 - 80℃; for 15.25h; Suzuki coupling; Inert atmosphere;99%
n-octyne
629-05-0

n-octyne

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

(E)-1,3,5-trimethyl-3-(oct-1-en-1-yl)benzene
1421336-58-4

(E)-1,3,5-trimethyl-3-(oct-1-en-1-yl)benzene

Conditions
ConditionsYield
Stage #1: n-octyne With bis(pentamethylcyclopentadienyl)zirconium(IV) dichloride; dichloroalane bis(tetrahydrofuran) solvate In tetrahydrofuran Reflux; Inert atmosphere;
Stage #2: 2,4,6-trimethylphenyl bromide With 1,4-diaza-bicyclo[2.2.2]octane; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; XPhos In tetrahydrofuran for 2h; Reflux; Inert atmosphere;
99%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

2,4,6-triisopropylphenylboronic acid
154549-38-9

2,4,6-triisopropylphenylboronic acid

2,4,6-triisopropyl-2',4',6'-trimethylbiphenyl

2,4,6-triisopropyl-2',4',6'-trimethylbiphenyl

Conditions
ConditionsYield
With BI-DIME; palladium diacetate; sodium t-butanolate In toluene at 110℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere;99%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

p-tolylboronic pinacol ester
195062-57-8

p-tolylboronic pinacol ester

2,4,4',6-tetramethyl-1,1'-biphenyl
3976-37-2

2,4,4',6-tetramethyl-1,1'-biphenyl

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide In neat (no solvent) at 110℃; for 24h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere;99%
furan
110-00-9

furan

indium(III) chloride

indium(III) chloride

2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

1,3,5-trimethyl 2-(α-furyl)benzene
81698-99-9

1,3,5-trimethyl 2-(α-furyl)benzene

Conditions
ConditionsYield
Stage #1: furan With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 0.5h; Inert atmosphere;
Stage #2: indium(III) chloride In tetrahydrofuran at -78 - 25℃; for 0.5h;
Stage #3: 2,4,6-trimethylphenyl bromide With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; dicylclohexylphosphino(2',4',6'-triisopropyl)biphenyl In tetrahydrofuran; methanol for 15h; Reflux;
99%
2,4,6-trimethylphenyl bromide
576-83-0

2,4,6-trimethylphenyl bromide

(2,6-dimethoxyphenyl)boronic acid
23112-96-1

(2,6-dimethoxyphenyl)boronic acid

2′,6′-dimethoxy-2,4,6-trimethyl-1,1′-biphenyl

2′,6′-dimethoxy-2,4,6-trimethyl-1,1′-biphenyl

Conditions
ConditionsYield
With [Pd(1,3-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazol-2-ylidene)(cinnamyl)Cl]; potassium 2-methylbutan-2-olate In 1,4-dioxane at 110℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere; Sealed tube;99%
With potassium phosphate; C29H37O2P; palladium diacetate In toluene at 110℃; for 3h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;81%

576-83-0Relevant articles and documents

-

Andrews,Keefer

, p. 4549,4552 (1956)

-

Molecular tweezers based on trivalent phosphine, preparation method of molecular tweezers, metal-molecular tweezers catalyst, and preparation method and application of metal-molecular tweezers catalyst

-

Paragraph 0038; 0059-0060, (2020/12/14)

The invention relates to the technical field of inorganic-metal organic crossing and relates to the technical field of molecular tweezers, in particular to molecular tweezers based on trivalent phosphine, a preparation method of the molecular tweezers, a metal-molecular tweezer catalyst, a preparation method of the metal-molecular tweezer catalyst and an application of the metal-molecular tweezercatalyst, the molecular tweezer based on trivalent phosphine is named as P-MV-PCN-521-R, and R is any one of benzoic acid, p-nitrobenzoic acid, formic acid, p-methylbenzoic acid and dichloroacetic acid. The molecular tweezers based on the trivalent phosphine have distance adjustability. The trivalent phosphine-based metal-molecular tweezer catalyst provided by the invention has a high crystallinesurface area and a high specific surface area. The trivalent phosphine-based metal-molecular tweezer catalyst has good chemical stability and thermal stability, and is a primary condition for applyingthe trivalent phosphine-based metal-molecular tweezer catalyst to the actual field. The trivalent phosphine-based metal-molecular tweezer catalyst with adjustable distance provided by the invention has good selectivity for bromination of aromatic compounds.

Preparation method of monobrominated aromatic hydrocarbon compound

-

Paragraph 0075-0080, (2020/11/23)

The invention discloses a preparation method of a monobrominated aromatic hydrocarbon compound, which comprises the following steps: by using an aromatic hydrocarbon compound as a raw material, wateras a solvent and liquid bromine as a bromine source, reacting at room temperature for 4.5 hours, and after the reaction is finished, carrying out aftertreatment on the obtained reaction mixed solutionto obtain the monobrominated target product. According to the method, a high-selectivity bromination method is realized on the aromatic hydrocarbon compound under the action of water, and the monobrominated aromatic hydrocarbon compound is prepared. The method is high in reaction applicability, mild in condition, high in yield, green and environment-friendly.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 576-83-0