57741-46-5

Basic information

• Product Name: 4,7,10,13-tetraoxahexadecanedinitrile
• Synonyms: 4,7,10,13-tetraoxahexadecanedinitrile;Einecs 260-924-7;Propanenitrile, 3,3'-(1,2-ethanediylbis(oxy-2,1-ethanediyloxy))bis-;4,7,10,13-tetraoxahexadecane-1,16-dinitrile
• CAS NO: 57741-46-5
• Molecular Formula: C₁₂H₂₀N₂O₄
• Molecular Weight: 256.2982
• EINECS: 260-924-7
• Mol File: 57741-46-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 427.3°Cat760mmHg
• Flash Point: 169.7°C
• Appearance: /
• Density: 1.073g/cm³
• Vapor Pressure: 1.66E-07mmHg at 25°C
• Refractive Index: 1.452
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4,7,10,13-tetraoxahexadecanedinitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7,10,13-tetraoxahexadecanedinitrile(57741-46-5)
• EPA Substance Registry System: 4,7,10,13-tetraoxahexadecanedinitrile(57741-46-5)

Safety Data

• Hazardous Substances Data: 57741-46-5(Hazardous Substances Data)

Usage

General Description

4,7,10,13-Tetraoxahexadecanedinitrile, also known as TOHDN, is a chemical compound with the molecular formula C10H6N2O6. It is a colorless and odorless solid that is primarily used as a crosslinking agent in the production of polymeric materials, such as epoxy resins and plastics. TOHDN has high thermal and chemical stability, making it an effective additive for enhancing the mechanical and thermal properties of polymers. It is also used as a flame retardant and in the formulation of adhesives and sealants. However, TOHDN is known to be toxic and can cause skin irritation, respiratory issues, and other adverse health effects if not handled properly. Due to its potential health hazards, proper safety measures and protective equipment are necessary when working with TOHDN.

InChI:InChI=1/C12H20N2O4/c13-3-1-5-15-7-9-17-11-12-18-10-8-16-6-2-4-14/h1-2,5-12H2

Upstream product

• 107-13-1 acrylonitrile 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 

Downstream Products

• 31127-82-9 Iodoxamic acid 
• 51134-98-6 C₃₆H₄₄I₆N₄O₁₂ 
• 25901-41-1 C₃₂H₃₆I₆N₄O₁₂ 
• 51211-03-1 C₃₀H₃₂I₆N₄O₁₂ 
• 13438-11-4 Triaethylenglykol-bis-(3-amino-propylaether) 
• 31127-85-2 4,7,10,13-tetraoxahexadecane-1,16-dioic acid 

Relevant articles and documents

BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY

The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Intramolecular End-to-End Reactions of Photoactive Terminal Groups Linked by Poly(oxyethylene) Chains

The triplet-sensitized photochemical reaction using a series of poly(oxyethylene) chains with a pair of photoactive terminal groups, dibenzazepine (DBA) chromophores (DBA-COCH2CH2(OCH2CH2)nOCH2CH2CO-DBA, n=0-10) was examined.The photoirradiation of bichromophoric compounds caused either intra- or intermolecular reactions.These reactions were kinetically analyzed by two different methods: the measurement of deactivation processes of the reaction intermediates (excited triplet state of DBA) by nanosecond laser photolysis and the quantitative analysis of the reaction products by GPC.The intramolecular deactivation rate constant, kintra, showed a remarkable chain-length dependence; the maximum kintra value appeared at n=5 and it was found to be 5.9X104 s-1.On the other hand, the intramolecular cyclization rate also depends on the chain length; the maximum quantum yield, φintrad, was given at n=7 (φintrad=0.51).The chain length for the maximum cyclization yield shifted slightly to the longer region than that for the maximum kintra value due to the restriction of the terminal structure (anti-configuration).The results obtained for this reaction system are compared with those obtained for the previously reported polymethylene system and the effect of chain flexibility on the intramolecular ring-closure reaction is discussed.