58117-53-6

Basic information

• Product Name: benzyl (S)-(5,6-diamino-6-oxohexyl)carbamate monohydrochloride
• Synonyms: benzyl (S)-(5,6-diamino-6-oxohexyl)carbamate monohydrochloride;N-α-Z-L-lysine amide hydrochloride;N-a-Z-L-lysineamidehydrochloride;H-Lys(Z)-NH2•CARBAMIC ACID, [(5S)-5,6-DIAMINO-6-OXOHEXYL]-, PHENYLMETHYL ESTER, MONOHYDROCHLORIDE;(S)-(5,6-Diamino-6-oxohexyl)carbamic acid phenylmethyl ester monohydrochloride;N6-Carbobenzoxy-L-lysinamide monohydrochloride;L-Lys(Z)-NH2·HCl
• CAS NO: 58117-53-6
• Molecular Formula: C₁₄H₂₁N₃O₃*ClH
• Molecular Weight: 315.79578
• EINECS: 261-136-6
• Product Categories: Amino Acids and Derivatives
• Mol File: 58117-53-6.mol

Chemical Properties

• Boiling Point: 527.1 °C at 760 mmHg
• Flash Point: 272.6 °C
• Appearance: /Solid
• Vapor Pressure: 3.36E-11mmHg at 25°C
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: benzyl (S)-(5,6-diamino-6-oxohexyl)carbamate monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (S)-(5,6-diamino-6-oxohexyl)carbamate monohydrochloride(58117-53-6)
• EPA Substance Registry System: benzyl (S)-(5,6-diamino-6-oxohexyl)carbamate monohydrochloride(58117-53-6)

Safety Data

• Hazardous Substances Data: 58117-53-6(Hazardous Substances Data)

Usage

Uses

H-Lys(z)-nh2 hcl

InChI:InChI=1/C14H21N3O3.ClH/c15-12(13(16)18)8-4-5-9-17-14(19)20-10-11-6-2-1-3-7-11;/h1-3,6-7,12H,4-5,8-10,15H2,(H2,16,18)(H,17,19);1H/t12-;/m0./s1

Upstream product

• 55592-81-9 N^ε-(benzyloxycarbonyl)-N^α-(tert-butoxycarbonyl)-L-lysinamide 
• 1155-64-2 N₆-[(benzyloxy)carbonyl]-L-lysine 
• 27894-50-4 methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride 
• 2389-45-9 Boc-Lys(Z)-OH 

Relevant articles and documents

DEUTERATED TETRAPEPTIDES THAT TARGET MITOCHONDRIA

Disclosed are deuterated analogs of SBT-20 and elamipretide (MTP-131). The compounds are useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.

Protease-catalysed synthesis of peptides containing histidine and lysine

The kinetically controlled α-chymotrypsin- and trypsin-catalysed syntheses of peptides starting from simple acyl donor esters containing histidine at the P1-position (nomenclature according to Schechter and Berger) and lysine derivatives as amino components were examined on the basis of their kinetic parameters. Despite higher specificity constants (k(cat)/K(M)) of trypsin-catalysed ester hydrolysis, α-chymotrypsin- catalysed acyl transfer to N(ε)unprotected lysine derivatives gave higher peptide yields as compared to trypsin-catalysed reactions, whereas in acyl transfer to N(ε)-protected lysine derivatives the trypsin-catalysed reaction gave higher yields. α-Chymotrypsin-catalysed acyl transfer reactions in frozen systems demonstrated the yield-enhancing effect of freezing. Using specific ester leaving groups, both the amount of enzyme and the reaction time can be reduced. In frozen systems the ε-amino function of H-Lys-OH acts as an acyl acceptor at pH ≤9.